Search Results - "ALBANI, Diego"

Organ-On-A-Chip in vitro Models of the Brain and the Blood-Brain Barrier and Their Value to Study the Microbiota-Gut-Brain Axis in Neurodegeneration by Raimondi, Ilaria, Izzo, Luca, Tunesi, Marta, Comar, Manola, Albani, Diego, Giordano, Carmen

“…We are accumulating evidence that intestinal microflora, collectively named gut microbiota, can alter brain pathophysiology, but researchers have just begun to…”
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Gene expression meta-analysis of Parkinson's disease and its relationship with Alzheimer's disease by Kelly, Jack, Moyeed, Rana, Carroll, Camille, Albani, Diego, Li, Xinzhong

“…Parkinson's disease (PD) and Alzheimer's disease (AD) are the most common neurodegenerative diseases and have been suggested to share common pathological and…”
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Neuroprotective properties of resveratrol in different neurodegenerative disorders by Albani, Diego, Polito, Letizia, Signorini, Alessandra, Forloni, Gianluigi

“…The natural phytocompound resveratrol has been considered for many years a potential anticancer drug, but recently it has come to the attention of…”
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Genomic dissection of pod shattering in common bean: mutations at non‐orthologous loci at the basis of convergent phenotypic evolution under domestication of leguminous species by Rau, Domenico, Murgia, Maria L., Rodriguez, Monica, Bitocchi, Elena, Bellucci, Elisa, Fois, Davide, Albani, Diego, Nanni, Laura, Gioia, Tania, Santo, Debora, Marcolungo, Luca, Delledonne, Massimo, Attene, Giovanna, Papa, Roberto

“…Summary The complete or partial loss of shattering ability occurred independently during the domestication of several crops. Therefore, the study of this trait…”
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Using integrated meta-omics to appreciate the role of the gut microbiota in epilepsy by Boeri, Lucia, Donnaloja, Francesca, Campanile, Marzia, Sardelli, Lorenzo, Tunesi, Marta, Fusco, Federica, Giordano, Carmen, Albani, Diego

“…The way the human microbiota may modulate neurological pathologies is a fascinating matter of research. Epilepsy is a common neurological disorder, which has…”
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Human Gut-Microbiota Interaction in Neurodegenerative Disorders and Current Engineered Tools for Its Modeling by Ceppa, Florencia Andrea, Izzo, Luca, Sardelli, Lorenzo, Raimondi, Ilaria, Tunesi, Marta, Albani, Diego, Giordano, Carmen

“…The steady increase in life-expectancy of world population, coupled to many genetic and environmental factors (for instance, pre- and post-natal exposures to…”
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Induced pluripotent stem cell-based organ-on-a-chip as personalized drug screening tools: A focus on neurodegenerative disorders by Fanizza, Francesca, Campanile, Marzia, Forloni, Gianluigi, Giordano, Carmen, Albani, Diego

“…The Organ-on-a-Chip (OoC) technology shows great potential to revolutionize the drugs development pipeline by mimicking the physiological environment and…”
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The nuclear import of the transcription factor MyoD is reduced in mesenchymal stem cells grown in a 3D micro-engineered niche by Jacchetti, Emanuela, Nasehi, Ramin, Boeri, Lucia, Parodi, Valentina, Negro, Alessandro, Albani, Diego, Osellame, Roberto, Cerullo, Giulio, Matas, Jose Felix Rodriguez, Raimondi, Manuela Teresa

“…Smart biomaterials are increasingly being used to control stem cell fate in vitro by the recapitulation of the native niche microenvironment. By integrating…”
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Molecular Analysis of the E2F/DP Gene Family of Daucus carota and Involvement of the DcE2F1 Factor in Cell Proliferation by Perrotta, Lara, Giordo, Roberta, Francis, Dennis, Rogers, Hilary J, Albani, Diego

“…E2F transcription factors are key components of the RB/E2F pathway that, through the action of cyclin-dependent kinases, regulates cell cycle progression in…”
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Increased transcription of transglutaminase 1 mediates neuronal death in in vitro models of neuronal stress and Aβ1–42-mediated toxicity by Tripathy, Debasmita, Migazzi, Alice, Costa, Federica, Roncador, Alessandro, Gatto, Pamela, Fusco, Federica, Boeri, Lucia, Albani, Diego, Juárez-Hernández, J. Leon, Musio, Carlo, Colombo, Laura, Salmona, Mario, Wilhelmus, M.M. Micha, Drukarch, Benjamin, Pennuto, Maria, Basso, Manuela

“…Alzheimer's disease (AD) is the most common cause of dementia. At the pre-symptomatic phase of the disease, the processing of the amyloid precursor protein…”
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Unravelling the mechanotransduction pathways in Alzheimer's disease by Donnaloja, Francesca, Limonta, Emma, Mancosu, Christian, Morandi, Francesco, Boeri, Lucia, Albani, Diego, Raimondi, Manuela Teresa

“…Alzheimer's disease (AD) represents one of the most common and debilitating neurodegenerative disorders. By the end of 2040, AD patients might reach 11.2…”
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Distinctive features and differential regulation of the DRTS genes of Arabidopsis thaliana by Maniga, Antonio, Ghisaura, Stefania, Perrotta, Lara, Marche, Maria Giovanna, Cella, Rino, Albani, Diego

“…In plants and protists, dihydrofolate reductase (DHFR) and thymidylate synthase (TS) are part of a bifunctional enzyme (DRTS) that allows efficient recycling…”
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A Comprehensive Phenotypic Investigation of the "Pod-Shattering Syndrome" in Common Bean by Murgia, Maria L, Attene, Giovanna, Rodriguez, Monica, Bitocchi, Elena, Bellucci, Elisa, Fois, Davide, Nanni, Laura, Gioia, Tania, Albani, Diego M, Papa, Roberto, Rau, Domenico

“…Seed shattering in crops is a key domestication trait due to its relevance for seed dispersal, yield, and fundamental questions in evolution (e.g., convergent…”
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The role of single-nucleotide variants of the energy metabolism-linked genes SIRT3, PPARGC1A and APOE in amyotrophic lateral sclerosis risk by Albani, Diego, Pupillo, Elisabetta, Bianchi, Elisa, Chierchia, Armando, Martines, Rosalba, Forloni, Gianluigi, Beghi, Ettore

“…Amyotrophic lateral sclerosis (ALS) is a multifactorial disease, possibly with contributions from genetics and lifestyle. We examined variants in genes…”
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DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70 by Batelli, Sara, Albani, Diego, Rametta, Raffaela, Polito, Letizia, Prato, Francesca, Pesaresi, Marzia, Negro, Alessandro, Forloni, Gianluigi

“…Parkinson's disease (PD) is a neurodegenerative pathology whose molecular etiopathogenesis is not known. Novel contributions have come from familial forms of…”
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AN ADVANCED IN VITRO TOOL TO STUDY GUT-BRAIN AXIS IN NEURODEGENERATION by Fanizza, Francesca, Boeri, Lucia, Negro, Francesca, Pugli, Francesca, Forloni, Gianluigi, Giordano, Carmen, Albani, Diego

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Advanced Organ-on-a-Chip Devices to Investigate Liver Multi-Organ Communication: Focus on Gut, Microbiota and Brain by Boeri, Lucia, Izzo, Luca, Sardelli, Lorenzo, Tunesi, Marta, Albani, Diego, Giordano, Carmen

“…The liver is a key organ that can communicate with many other districts of the human body. In the last few decades, much interest has focused on the…”
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Loss of exosomes in progranulin-associated frontotemporal dementia by Benussi, Luisa, Ciani, Miriam, Tonoli, Elisa, Morbin, Michela, Palamara, Luisa, Albani, Diego, Fusco, Federica, Forloni, Gianluigi, Glionna, Michela, Baco, Monika, Paterlini, Anna, Fostinelli, Silvia, Santini, Benedetta, Galbiati, Elisabetta, Gagni, Paola, Cretich, Marina, Binetti, Giuliano, Tagliavini, Fabrizio, Prosperi, Davide, Chiari, Marcella, Ghidoni, Roberta

“…Abstract Many cells of the nervous system have been shown to release exosomes, a subclass of secreted vesicles of endosomal origin capable of transferring…”
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Evaluation of Neuroinflammatory Contribution to Neurodegeneration in LRRK2 Drosophila Models by Nguyen, Hoai Nam, Galleri, Grazia, Rassu, Antonio, Ciampelli, Cristina, Bernardoni, Roberto, Galioto, Manuela, Albani, Diego, Crosio, Claudia, Iaccarino, Ciro

“…Pathological mutations in the gene are the major genetic cause of Parkinson's disease (PD). Although several animal models with either LRRK2 down- or…”
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3D brain tissue physiological model with co-cultured primary neurons and glial cells in hydrogels by Raimondi, Ilaria, Tunesi, Marta, Forloni, Gianluigi, Albani, Diego, Giordano, Carmen

“…Recently, researchers have focused on the role of gut microbiota on human health and reported the existence of a bidirectional relationship between intestinal…”
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