Search Results - "ALAVA, Maria Angeles"

Mitochondrial respiratory chain and thioredoxin reductase regulate intermembrane Cu,Zn-superoxide dismutase activity: implications for mitochondrial energy metabolism and apoptosis by Iñarrea, Pedro, Moini, Hadi, Han, Derick, Rettori, Daniel, Aguiló, Ignacio, Alava, Maria Angeles, Iturralde, María, Cadenas, Enrique

“…IMS (intermembrane space) SOD1 (Cu/Zn-superoxide dismutase) is inactive in isolated intact rat liver mitochondria and is activated following oxidative…”
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Melatonin and steroid hormones activate intermembrane Cu,Zn-superoxide dismutase by means of mitochondrial cytochrome P450 by Iñarrea, Pedro, Casanova, Alvaro, Alava, Maria Angeles, Iturralde, María, Cadenas, Enrique

“…Melatonin and steroid hormones are cytochrome P450 (CYP or P450; EC 1.14.14.1) substrates that have antioxidant properties and mitochondrial protective…”
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Differential Secretion of Fas Ligand- or APO2 Ligand/TNF-Related Apoptosis-Inducing Ligand-Carrying Microvesicles During Activation-Induced Death of Human T Cells by Monleon, Inmaculada, Martinez-Lorenzo, Maria Jose, Monteagudo, Luis, Lasierra, Pilar, Taules, Marta, Iturralde, Maria, Pineiro, Andres, Larrad, Luis, Alava, Maria Angeles, Naval, Javier, Anel, Alberto

“…Preformed Fas ligand (FasL) and APO2 ligand (APO2L)/TNF-related apoptosis-inducing ligand (TRAIL) are stored in the cytoplasm of the human Jurkat T cell line…”
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Apo2L/TRAIL and immune regulation by Anel, Alberto, Bosque, Alberto, Naval, Javier, Pineiro, Andres, Larrad, Luis, Alava, Maria Angeles, Martinez-Lorenzo, Maria Jose

“…Apo2L/TRAIL is a member of the TNF family, with its receptors DR4 and DR5 containing a death domain. Multiple tumors are sensitive to Apo2L/TRAIL-induced…”
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Rheumatoid synovial fluid T cells are sensitive to APO2L/TRAIL by Martínez-Lorenzo, María José, Anel, Alberto, Saez-Gutierrez, Berta, Royo-Cañas, María, Bosque, Alberto, Alava, María Angeles, Piñeiro, Andrés, Lasierra, Pilar, Asín-Ungría, Jaime, Larrad, Luis

“…Abstract The infiltration and accumulation of T cells in the rheumatoid arthritis (RA) synovial fluid (SF) are hallmarks of disease. We aimed to assess the…”
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Comparative proteomics of exosomes secreted by tumoral Jurkat T cells and normal human T cell blasts unravels a potential tumorigenic role for valosin-containing protein by Bosque, Alberto, Dietz, Lisa, Gallego-Lleyda, Ana, Sanclemente, Manuel, Iturralde, María, Naval, Javier, Alava, María Angeles, Martínez-Lostao, Luis, Thierse, Hermann-Josef, Anel, Alberto

“…We have previously characterized that FasL and Apo2L/TRAIL are stored in their bioactive form inside human T cell blasts in intraluminal vesicles present in…”
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Cytotoxicity of quinone drugs on highly proliferative human leukemia T cells: Reactive oxygen species generation and inactive shortened SOD1 isoform implications by Aguiló, Juan Ignacio, Iturralde, María, Monleón, Inmaculada, Iñarrea, Pedro, Pardo, Julián, Martínez-Lorenzo, María José, Anel, Alberto, Alava, María Angeles

“…► Cytotoxicity of quinone drugs on hyperproliferative leukemia T cells is assessed. ► The mechanism of quinone drugs is mediated by Reactive Oxygen Species…”
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Lack of Fas/CD95 surface expression in highly proliferative leukemic cell lines correlates with loss of CtBP/BARS and redirection of the protein toward giant lysosomal structures by MONLEON, Inmaculada, ITURRALDE, Maria, MARTINEZ-LORENZO, Maria José, MONTEAGUDO, Luis, LASIERRA, Pilar, LARRAD, Luis, PINEIRO, Andrés, NAVAL, Javier, ALAVA, Maria Angeles, ANEL, Alberto

“…Fas/CD95 is a type-I membrane glycoprotein, which inducesapoptotic cell death when ligated by its physiological ligand. We generated previously…”
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Acute phase protein haptoglobin as inflammatory marker in serum and synovial fluid in an equine model of arthritis by Barrachina, Laura, Remacha, Ana Rosa, Soler, Lourdes, García, Natalia, Romero, Antonio, Vázquez, Francisco José, Vitoria, Arantza, Álava, María Ángeles, Lamprave, Fermín, Rodellar, Clementina

“…•Serum and synovial haptoglobin were measured pre- and post-arthritis induction.•Haptoglobin increase in arthritis is significant in both serum and synovial…”
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Down-regulation of normal human T cell blast activation: roles of APO2L/TRAIL, FasL, and c- FLIP, Bim, or Bcl-x isoform expression by Bosque, Alberto, Pardo, Julián, Martínez‐Lorenzo, Mª José, Iturralde, María, Marzo, Isabel, Piñeiro, Andrés, Alava, Mª Angeles, Naval, Javier, Anel, Alberto

“…A systematic study was undertaken to characterize the role of APO 2 ligand/tumor necrosis factor‐related apoptosis‐inducing ligand (APO2L/TRAIL) and Fas ligand…”
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Saturated free fatty acid release and intracellular ceramide generation during apoptosis induction are closely related processes by Iturralde, Marı́a, Gamen, Susana, Pardo, Julián, Bosque, Alberto, Piñeiro, Andrés, Alava, Marı́a Angeles, Naval, Javier, Anel, Alberto

“…Apoptosis induced by cells from the immune system is frequently associated with an increase in the ceramide content of target cells, due to the activation of…”
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La capacidad jurídica de los discapacitados intelectuales y sus derechos como consumidores en Ecuador según la Convención de los derechos de las personas con discapacidad by Friend Macías, Robert Alexander, Álava Díaz, María de los Ángeles

“…La presente investigación analiza el ordenamiento jurídico ecuatoriano relacionado con los derechos como consumidores de las personas con discapacidad…”
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