Search Results - "AKSOY, Serap"
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Tsetse peritrophic matrix influences for trypanosome transmission
Published in Journal of insect physiology (01-10-2019)“…[Display omitted] •Tsetse PM is constitutively produced by cardia and lines the entire gut.•PM prevents epithelial immune induction against resident…”
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Insect Gut Microbiota: Accessories to the Bite
Published in Cell host & microbe (10-01-2018)“…The Leishmania parasite is transmitted via the bite of a sand fly. In this issue of Cell Host & Microbe, Dey et al. (2018) report that sand fly gut microbiota…”
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3
PGRP-LB is a maternally transmitted immune milk protein that influences symbiosis and parasitism in tsetse’s offspring
Published in Proceedings of the National Academy of Sciences - PNAS (26-06-2012)“…Beneficial microbe functions range from host dietary supplementation to development and maintenance of host immune system. In mammals, newborn progeny are…”
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Strong Local Scientific Communities Are Essential to Reach the Millennium Development Goals
Published in PLoS neglected tropical diseases (01-10-2015)“… Among the 17 diseases classified as NTDs by the World Health Organization are Chagas disease, human African trypanosomiasis, and leishmaniases caused by…”
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PLOS Neglected Tropical Diseases: Ten years of progress in neglected tropical disease control and elimination … More or less
Published in PLoS neglected tropical diseases (20-04-2017)“…This year PLOS Neglected Tropical Diseases (PLOS NTDs) celebrates its tenth anniversary following the publication of the first issue in 2007 [1]. When PLOS…”
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Sleeping sickness elimination in sight: time to celebrate and reflect, but not relax
Published in PLoS neglected tropical diseases (22-02-2011)Get full text
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7
What constitutes a neglected tropical disease?
Published in PLoS neglected tropical diseases (01-01-2020)“…The World Health Organization (WHO) currently classifies 20 diseases and conditions as neglected tropical diseases (NTDs). However, since its inception in…”
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Tick-Borne Diseases in Turkey: A Review Based on One Health Perspective
Published in PLoS neglected tropical diseases (15-12-2016)“…The importance of tick-borne diseases is increasing all over the world, including Turkey. Global warming, environmental and ecological changes and the…”
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Journal Article Book Review -
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Obligate symbionts activate immune system development in the tsetse fly
Published in The Journal of immunology (1950) (01-04-2012)“…Many insects rely on the presence of symbiotic bacteria for proper immune system function. However, the molecular mechanisms that underlie this phenomenon are…”
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Human African trypanosomiasis control: Achievements and challenges
Published in PLoS neglected tropical diseases (20-04-2017)“…Sleeping sickness, also known as human African trypanosomiasis (HAT), is a neglected disease that impacts 70 million people living in 1.55 million km2 in…”
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Tsetse immune system maturation requires the presence of obligate symbionts in larvae
Published in PLoS biology (01-05-2011)“…Beneficial microbial symbionts serve important functions within their hosts, including dietary supplementation and maintenance of immune system homeostasis…”
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Symbiont-induced odorant binding proteins mediate insect host hematopoiesis
Published in eLife (12-01-2017)“…Symbiotic bacteria assist in maintaining homeostasis of the animal immune system. However, the molecular mechanisms that underlie symbiont-mediated host…”
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Obligate Mutualist Wigglesworthia glossinidia Influences Reproduction, Digestion, and Immunity Processes of Its Host, the Tsetse Fly
Published in Applied and Environmental Microbiology (01-10-2008)“…Tsetse flies (Diptera: Glossinidae) are vectors for trypanosome parasites, the agents of the deadly sleeping sickness disease in Africa. Tsetse also harbor two…”
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Interactions between mutualist Wigglesworthia and tsetse peptidoglycan recognition protein (PGRP-LB) influence trypanosome transmission
Published in Proceedings of the National Academy of Sciences - PNAS (21-07-2009)“…Tsetse flies, the sole vectors of African trypanosomes, have coevolved with mutualistic endosymbiont Wigglesworthia glossinidiae. Elimination of Wigglesworthia…”
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World neglected tropical diseases day
Published in PLoS neglected tropical diseases (01-01-2020)“…January 30, 2020 is the first-ever World Neglected Tropical Diseases Day (World NTD Day), a day when we celebrate the achievements made towards control of the…”
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Unravelling the relationship between the tsetse fly and its obligate symbiont Wigglesworthia: transcriptomic and metabolomic landscapes reveal highly integrated physiological networks
Published in Proceedings of the Royal Society. B, Biological sciences (28-06-2017)“…Insects with restricted diets rely on obligate microbes to fulfil nutritional requirements essential for biological function. Tsetse flies, vectors of African…”
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Eliminating the Neglected Tropical Diseases: Translational Science and New Technologies
Published in PLoS neglected tropical diseases (02-03-2016)“…Today, the World Health Organization recognizes 17 major parasitic and related infections as the neglected tropical diseases (NTDs). Despite recent gains in…”
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Journal Article Book Review -
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Adenotrophic Viviparity in Tsetse Flies: Potential for Population Control and as an Insect Model for Lactation
Published in Annual Review of Entomology (07-01-2015)“…Tsetse flies ( Glossina spp.), vectors of African trypanosomes, are distinguished by their specialized reproductive biology, defined by adenotrophic viviparity…”
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Journal Article Book Chapter -
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Tissue distribution and transmission routes for the tsetse fly endosymbionts
Published in Journal of invertebrate pathology (01-03-2013)“…[Display omitted] ► Three symbionts and a DNA virus reside in different tsetse tissues. ► Availability of GmmWig− and GmmApo enables analysis of intercommunity…”
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Journal Article Conference Proceeding -
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Impact of vector biology research on old and emerging neglected tropical diseases
Published in PLoS neglected tropical diseases (31-05-2018)“…About the Authors: Jesus G. Valenzuela * E-mail: jvalenzuela@niaid.nih.gov (JGV); serap.aksoy@yale.edu (SA) Affiliation: Vector Molecular Biology Section,…”
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