Search Results - "AKIYOSHI, K"

Open-label phase II study of the efficacy of nivolumab for cancer of unknown primary by Tanizaki, J., Yonemori, K., Akiyoshi, K., Minami, H., Ueda, H., Takiguchi, Y., Miura, Y., Segawa, Y., Takahashi, S., Iwamoto, Y., Kidera, Y., Fukuoka, K., Ito, A., Chiba, Y., Sakai, K., Nishio, K., Nakagawa, K., Hayashi, H.

“…Cancer of unknown primary (CUP) has a poor prognosis. Given the recent approval of immune checkpoint inhibitors for several cancer types, we carried out a…”
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Regulatory B cells limit CNS inflammation and neurologic deficits in murine experimental stroke by Ren, Xuefang, Akiyoshi, Kozaburo, Dziennis, Suzan, Vandenbark, Arthur A, Herson, Paco S, Hurn, Patricia D, Offner, Halina

“…Evaluation of infarct volumes and infiltrating immune cell populations in mice after middle cerebral artery occlusion (MCAO) strongly implicates a mixture of…”
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REVERCE: a randomized phase II study of regorafenib followed by cetuximab versus the reverse sequence for previously treated metastatic colorectal cancer patients by Shitara, K., Yamanaka, T., Denda, T., Tsuji, Y., Shinozaki, K., Komatsu, Y., Kobayashi, Y., Furuse, J., Okuda, H., Asayama, M., Akiyoshi, K., Kagawa, Y., Kato, T., Oki, E., Ando, T., Hagiwara, Y., Ohashi, Y., Yoshino, T.

“…The objective of this randomized phase II trial was to evaluate efficacy and safety of the therapeutic sequence of regorafenib followed by cetuximab, compared…”
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Nanogel-based nasal ghrelin vaccine prevents obesity by Azegami, T, Yuki, Y, Sawada, S, Mejima, M, Ishige, K, Akiyoshi, K, Itoh, H, Kiyono, H

“…Obesity is associated with multiple comorbidities such as cardiovascular diseases and has a huge economic impact on the health-care system. However, the…”
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Nanogel-based pneumococcal surface protein A nasal vaccine induces microRNA-associated Th17 cell responses with neutralizing antibodies against Streptococcus pneumoniae in macaques by Fukuyama, Y, Yuki, Y, Katakai, Y, Harada, N, Takahashi, H, Takeda, S, Mejima, M, Joo, S, Kurokawa, S, Sawada, S, Shibata, H, Park, E J, Fujihashi, K, Briles, D E, Yasutomi, Y, Tsukada, H, Akiyoshi, K, Kiyono, H

“…We previously established a nanosized nasal vaccine delivery system by using a cationic cholesteryl group-bearing pullulan nanogel (cCHP nanogel), which is a…”
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Efficacy and safety of nivolumab monotherapy for metastatic gastric cancer by Akiyoshi, K., Tsuboguchi, Y., Ueda, S., Okazaki, S., Tsuya, A., Tokunaga, S., Daga, H.

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TAS-102 followed by regorafenib or the reverse sequence in advanced colorectal cancer by Nakatani, Y., Ueda, S., Tsuboguchi, Y., Yoshii, Y., Akiyoshi, K., Tsuya, A., Okazaki, S., Tokunaga, S., Daga, H.

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Sidedness of the primary tumor on the effect of TAS-102 for refractory metastatic colorectal cancer by Ueda, S, Tsuboguchi, Y, Nakatani, Y, Tsuya, A, Nishina, S-I, Akiyoshi, K, Okazaki, S, Tokunaga, S, Daga, H

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Single molecular mechanics of a cholesterol-bearing pullulan nanogel at the hydrophobic interfaces by Lee, ImShik, Akiyoshi, K.

“…The study of nanogel (hydrogel nanoparticle) has intensified in the last decade due to the enormous potential applications in biomimetics, biosensors,…”
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Liposome chaperon in cell-free membrane protein synthesis: one-step preparation of KcsA-integrated liposomes and electrophysiological analysis by the planar bilayer method by Ando, M, Akiyama, M, Okuno, D, Hirano, M, Ide, T, Sawada, S, Sasaki, Y, Akiyoshi, K

“…Chaperoning functions of liposomes were investigated using cell-free membrane protein synthesis. KcsA potassium channel-reconstituted liposomes were prepared…”
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Effective CpG DNA delivery using amphiphilic cycloamylose nanogels by Tahara, Y, Yasuoka, J, Sawada, S, Sasaki, Y, Akiyoshi, K

“…Unmethylated CpG oligodeoxynucleotides induce inflammatory immune responses through cytokine production and have attracted increasing attention as an…”
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REVERCE: Randomized phase II study of regorafenib followed by cetuximab versus the reverse sequence for metastatic colorectal cancer patients previously treated with fluoropyrimidine, oxaliplatin, and irinotecan: Quality of life analysis by Yoshino, T., Yamanaka, T., Denda, T., Tsuji, Y., Shinozaki, K., Komatsu, Y., Kobayashi, Y., Furuse, J., Okuda, H., Asayama, M., Akiyoshi, K., Kagawa, Y., Kato, T., Oki, E., Ando, T., Hagiwara, Y., Ohashi, Y., Shitara, K.

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Sex-Driven Differences in the Effectiveness of Individualized Clinical Management of Alzheimer’s Disease Risk by Saif, N., Hristov, H., Akiyoshi, K., Niotis, K., Ariza, I. E., Malviya, N., Lee, P., Melendez, J., Sadek, G., Hackett, K., Rahman, A., Meléndez-Cabrero, J., Greer, C. E., Mosconi, L., Krikorian, R., Isaacson, Richard S.

“…Background The Comparative Effectiveness Dementia & Alzheimer’s Registry (CEDAR) trial demonstrated that individualized, multi-domain interventions improved…”
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11 Use of IHC and DISH of EGFR to evaluate efficacy of anti-EGFR drugs in KRAS-WT patients with mCRC by Takahashi, N, Yamada, Y, Taniguchi, H, Akiyoshi, K, Honma, Y, Iwasa, S, Kato, K, Hamaguchi, T, Shimada, Y

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Autonomous Mobile Robot Navigation Considering the Pedestrian Flow Intersections by Akiyoshi, K., Chugo, D., Muramatsu, S., Yokota, S., Hashimoto, H.

“…In recent years, many service robots move autonomously in an human co-existing environments. In these environments, there are multiple pedestrian flows and…”
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105P The efficacy of nivolumab monotherapy for advanced gastric cancer depends on the HER2 status by Nishibori, Y., Akiyoshi, K., Omori, R., Nakatani, Y., Akaishi, Y., Tanaka, A., Tokunaga, S., Daga, H.

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114P Risk factors for oesophageal fistula: A life-threatening complication of treatment for oesophageal cancer by Omori, R., Akiyoshi, K., Nishibori, Y., Nakatani, Y., Akaishi, Y., Tanaka, A., Tokunaga, S., Daga, H.

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Nanoparticle of cholesterol-bearing pullulan as a carrier of anticancer drugs by Satoh, K, Chen, F, Aoyama, A, Date, H, Akiyoshi, K

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Inhibitory effect of TS-962 on the formation of early atherosclerotic lesions in high fat-fed hyperlipidemic hamsters by Asami, Y., Yamagishi, I., Akiyoshi, K., Tomoike, H., Tsuchida, K., Higuchi, S.

“…The hypocholesterolemic and anti-atherosclerotic effect of TS-962, a specific ACAT inhibitor, was investigated in a hamster model fed a high fat diet…”
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Effects of olprinone, a new phosphodiesterase inhibitor, on gastric intramucosal acidosis and systemic inflammatory responses following hypothermic cardiopulmonary bypass by Yamaura, K., Akiyoshi, K., Irita, K., Taniyama, T., Takahashi, S.

“…Background: Phosphodiesterase (PDE) III inhibitors have both an inotropic and a peripheral vasodilatory effect, and also inhibit the activation of macrophages…”
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