Search Results - "AKASU, Takayuki"

Postoperative morbidity and mortality after mesorectal excision with and without lateral lymph node dissection for clinical stage II or stage III lower rectal cancer (JCOG0212): results from a multicentre, randomised controlled, non-inferiority trial by Fujita, Shin, Dr, Akasu, Takayuki, MD, Mizusawa, Junki, MSc, Saito, Norio, MD, Kinugasa, Yusuke, MD, Kanemitsu, Yukihide, MD, Ohue, Masayuki, MD, Fujii, Shoichi, MD, Shiozawa, Manabu, MD, Yamaguchi, Takashi, MD, Moriya, Yoshihiro, MD

“…Summary Background Mesorectal excision is the international standard surgical procedure for lower rectal cancer. However, lateral pelvic lymph node metastasis…”
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Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker by Takawa, Masashi, Masuda, Ken, Kunizaki, Masaki, Daigo, Yataro, Takagi, Katsunori, Iwai, Yukiko, Cho, Hyun‐Soo, Toyokawa, Gouji, Yamane, Yuka, Maejima, Kazuhiro, Field, Helen I., Kobayashi, Takaaki, Akasu, Takayuki, Sugiyama, Masanori, Tsuchiya, Eijyu, Atomi, Yutaka, Ponder, Bruce A. J., Nakamura, Yusuke, Hamamoto, Ryuji

“…The emphasis in anticancer drug discovery has always been on finding a drug with great antitumor potential but few side‐effects. This can be achieved if the…”
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MicroRNA expression profiling of exfoliated colonocytes isolated from feces for colorectal cancer screening by Koga, Yoshikatsu, Yasunaga, Masahiro, Takahashi, Amane, Kuroda, Junichiro, Moriya, Yoshihiro, Akasu, Takayuki, Fujita, Shin, Yamamoto, Seiichiro, Baba, Hideo, Matsumura, Yasuhiro

“…To reduce the colorectal cancer (CRC) mortality rate, we have reported several CRC screening methods using colonocytes isolated from feces. Expression analysis…”
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Histone Lysine Methyltransferase SETD8 Promotes Carcinogenesis by Deregulating PCNA Expression by TAKAWA, Masashi, CHO, Hyun-Soo, DOHMAE, Naoshi, FIELD, Helen I, TSUNODA, Tatsuhiko, KOBAYASHI, Takaaki, AKASU, Takayuki, SUGIYAMA, Masanori, OHNUMA, Shin-Ichi, ATOMI, Yutaka, PONDER, Bruce A. J, NAKAMURA, Yusuke, HAYAMI, Shinya, HAMAMOTO, Ryuji, TOYOKAWA, Gouji, KOGURE, Masaharu, YAMANE, Yuka, IWAI, Yukiko, MAEJIMA, Kazuhiro, UEDA, Koji, MASUDA, Akiko

“…Although the physiologic significance of lysine methylation of histones is well known, whether lysine methylation plays a role in the regulation of nonhistone…”
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Induction of the Stem-like Cell Regulator CD44 by Rho Kinase Inhibition Contributes to the Maintenance of Colon Cancer―Initiating Cells by OHATA, Hirokazu, ISHIGURO, Tatsuya, OKAMOTO, Koji, AIHARA, Yuki, SATO, Ai, SAKAI, Hiroaki, SEKINE, Shigeki, TANIGUCHI, Hirokazu, AKASU, Takayuki, FUJITA, Shin, NAKAGAMA, Hitoshi

“…The difficulty in expanding cancer-initiating cells in vitro is one of major obstacles for their biochemical characterization. We found that Rho kinase (ROCK)…”
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Predictive factors of pathological lateral pelvic lymph node metastasis in patients without clinical lateral pelvic lymph node metastasis (clinical stage II/III): The analysis of data from the clinical trial (JCOG0212) by Komori, Koji, Fujita, Shin, Mizusawa, Junki, Kanemitsu, Yukihide, Ito, Masaaki, Shiomi, Akio, Ohue, Masayuki, Ota, Mitsuyoshi, Akazai, Yoshihiro, Shiozawa, Manabu, Yamaguchi, Takashi, Bandou, Hiroyuki, Katsumata, Kenji, Kinugasa, Yusuke, Takii, Yasumasa, Akasu, Takayuki, Moriya, Yoshihiro

“…Mesorectal excision (ME) is the standard surgical procedure for lower rectal cancer. However, in Japan, total or tumor-specific ME with lateral pelvic lymph…”
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Accuracy of High-Resolution Magnetic Resonance Imaging in Preoperative Staging of Rectal Cancer by Akasu, Takayuki, Iinuma, Gen, Takawa, Masashi, Yamamoto, Seiichiro, Muramatsu, Yukio, Moriyama, Noriyuki

“…Background To achieve better prognosis and quality of life for patients with rectal cancer, extent of surgery and neoadjuvant chemoradiotherapy should…”
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Risk factors for surgical site infection and association of surgical site infection with survival of lower rectal cancer patients without clinical lateral pelvic lymph node metastasis (clinical Stage II/III): Analysis of data from JCOG0212 by Katsumata, Kenji, Enomoto, Masanobu, Ishizaki, Tetsuo, Fujita, Shin, Kanemitsu, Yukihide, Ito, Masaaki, Shiomi, Akio, Komori, Koji, Ohue, Masayuki, Ota, Mitsuyoshi, Akazai, Yoshihiro, Shiozawa, Manabu, Yamaguchi, Takashi, Bando, Hiroyuki, Sekimoto, Mitugu, Kobatake, Takaya, Machida, Ryunosuke, Akasu, Takayuki, Moriya, Yoshihiro

“…This study aimed to examine the risk factors for surgical site infection (SSI) and the association of that with recurrence in JCOG0212. The results for…”
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Risk factors for anastomotic leakage after laparoscopic surgery for rectal cancer using a stapling technique by Yamamoto, Seiichiro, Fujita, Shin, Akasu, Takayuki, Inada, Ryo, Moriya, Yoshihiro, Yamamoto, Seiichiro

“…This study evaluated the risk factors for anastomotic leakage after laparoscopic surgery for rectal cancer using a stapling technique. The total prospective…”
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Prognostic and predictive value of extended RAS mutation and mismatch repair status in stage III colorectal cancer by Sasaki, Yusuke, Akasu, Takayuki, Saito, Norio, Kojima, Hiroshi, Matsuda, Keiji, Nakamori, Shoji, Komori, Koji, Amagai, Kenji, Yamaguchi, Tatsuro, Ohue, Masayuki, Nagashima, Kengo, Yamada, Yasuhide

“…The prognostic and predictive value of KRAS gene mutations in stage III colorectal cancer is controversial because many recent clinical trials have not…”
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Risk factors of lateral pelvic lymph node metastasis in advanced rectal cancer by Fujita, Shin, Yamamoto, Seiichiro, Akasu, Takayuki, Moriya, Yoshihiro

“…Background To clarify the risk factors of lateral pelvic lymph node (LPLN) metastasis of rectal cancer, we examined associations between LPLN status and…”
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Pelvic exenteration for clinical T4 rectal cancer: Oncologic outcome in 93 patients at a single institution over a 30-year period by Ishiguro, Seiji, MD, Akasu, Takayuki, MD, Fujita, Shin, MD, Yamamoto, Seiichiro, MD, Kusters, Miranda, MSc, Moriya, Yoshihiro, MD

“…Background Patients with stage T4 rectal cancer are known to have poor survival and often require pelvic exenteration (PE). We describe the oncologic outcome…”
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Plasma concentrations of VCAM‐1 and PAI‐1: A predictive biomarker for post‐operative recurrence in colorectal cancer by Yamada, Yasuhide, Arao, Tokuzo, Matsumoto, Kazuko, Gupta, Vinita, Tan, Woei, Fedynyshyn, Joe, Nakajima, Takako E., Shimada, Yasuhiro, Hamaguchi, Tetsuya, Kato, Ken, Taniguchi, Hirokazu, Saito, Yutaka, Matsuda, Takahisa, Moriya, Yoshihiro, Akasu, Takayuki, Fujita, Shin, Yamamoto, Seiichiro, Nishio, Kazuto

“…This prospective study used antibody suspension bead arrays to identify biomarkers capable of predicting post‐operative recurrence with distal metastasis in…”
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Inhibition of intestinal polyp growth by oral ingestion of bovine lactoferrin and immune cells in the large intestine by Iigo, Masaaki, Alexander, David B., Xu, Jiegou, Futakuchi, Mitsuru, Suzui, Masumi, Kozu, Takahiro, Akasu, Takayuki, Saito, Daizo, Kakizoe, Tadao, Yamauchi, Koji, Abe, Fumiaki, Takase, Mitsunori, Sekine, Kazunori, Tsuda, Hiroyuki

“…Studies using animal models have demonstrated that ingestion of bovine lactoferrin (bLF) inhibits carcinogenesis in the colon and other organs of experimental…”
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A case-matched comparison of the short-term outcomes between laparoscopic and open abdominoperineal resection for rectal cancer by Inada, Ryo, Yamamoto, Seiichiro, Oshiro, Taihei, Takawa, Masashi, Fujita, Shin, Akasu, Takayuki

“…Purpose The aim of this study was to evaluate the short-term surgical outcomes of laparoscopic abdominoperineal resection (APR) for rectal cancer, by comparing…”
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Cancer prevention by bovine lactoferrin: from animal studies to human trial by Tsuda, Hiroyuki, Kozu, Takahiro, Iinuma, Gen, Ohashi, Yasuo, Saito, Yutaka, Saito, Daizo, Akasu, Takayuki, Alexander, David B, Futakuchi, Mitsuru, Fukamachi, Katsumi, Xu, Jiegou, Kakizoe, Tadao, Iigo, Masaaki

“…Colorectal cancer (CRC) is one of the most frequently diagnosed cancers and, despite improved colonoscopic screening, CRC is a leading cause of death from…”
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Risk Factors for Anastomotic Leakage Following Intersphincteric Resection for Very Low Rectal Adenocarcinoma by Akasu, Takayuki, Takawa, Masashi, Yamamoto, Seiichiro, Yamaguchi, Tomohiro, Fujita, Shin, Moriya, Yoshihiro

“…Background The aim of this study was to perform a retrospective analysis of the risk factors for anastomotic leakage following intersphincteric resection (ISR)…”
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Clinicopathological characteristics and prognostic factors of advanced colorectal mucinous adenocarcinoma by Yamaguchi, Tomohiro, Taniguchi, Hirokazu, Fujita, Shin, Sekine, Shigeki, Yamamoto, Seiichiro, Akasu, Takayuki, Kushima, Ryoji, Tani, Tohru, Moriya, Yoshihiro, Shimoda, Tadakazu

“…Yamaguchi T, Taniguchi H, Fujita S, Sekine S, Yamamoto S, Akasu T, Kushima R, Tani T, Moriya Y & Shimoda T 
(2012) Histopathology 61, 162–169…”
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Effect of orally administered bovine lactoferrin on the growth of adenomatous colorectal polyps in a randomized, placebo-controlled clinical trial by Kozu, Takahiro, Iinuma, Gen, Ohashi, Yasuo, Saito, Yutaka, Akasu, Takayuki, Saito, Daizo, Alexander, David B, Iigo, Masaaki, Kakizoe, Tadao, Tsuda, Hiroyuki

“…Lactoferrin (LF), a secreted, iron binding glycoprotein originally discovered as a component of milk, is found in a variety of exocrine secretions and in the…”
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Incidence and Patterns of Recurrence after Intersphincteric Resection for Very Low Rectal Adenocarcinoma by Akasu, Takayuki, MD, Takawa, Masashi, MD, Yamamoto, Seiichiro, MD, Fujita, Shin, MD, Moriya, Yoshihiro, MD

“…Background The aim of this study was to evaluate the incidence and patterns of recurrence, or oncologic safety, after intersphincteric resection (ISR) without…”
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