Search Results - "AKASHI, Makoto"
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1
Study protocol for the Fukushima Health Management Survey
Published in Journal of epidemiology (2012)“…The accidents that occurred at the Fukushima Daiichi Nuclear Power Plant after the Great East Japan Earthquake on 11 March 2011 have resulted in long-term,…”
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2
Role of the clock gene Period3 in the human cell‐autonomous circadian clock
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-02-2019)“…Previous studies have shown that mouse Period3 (mPer3) is dispensable for the generation of autonomous oscillations in the circadian clock. However, human…”
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Health effects of radiation and other health problems in the aftermath of nuclear accidents, with an emphasis on Fukushima
Published in The Lancet (British edition) (01-08-2015)“…Summary 437 nuclear power plants are in operation at present around the world to meet increasing energy demands. Unfortunately, five major nuclear accidents…”
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Bright light improves sleep in patients with Parkinson’s disease: possible role of circadian restoration
Published in Scientific reports (14-05-2020)“…Parkinson’s disease (PD) is one of the most common neurodegenerative disorders. Among the most common manifestations of PD are sleep problems, which are…”
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5
The Role of the Endocrine System in Feeding-Induced Tissue-Specific Circadian Entrainment
Published in Cell reports (Cambridge) (24-07-2014)“…The circadian clock is entrained to environmental cycles by external cue-mediated phase adjustment. Although the light input pathway has been well defined, the…”
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Measurements of Individual Radiation Doses in Residents Living Around the Fukushima Nuclear Power Plant
Published in Radiation research (01-11-2013)“…At the outset of the accident at Fukushima Daiichi Nuclear Power Plant in March 2011, the radiation doses experienced by residents were calculated from the…”
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7
Potential role of the pancreatic hormone insulin in resetting human peripheral clocks
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-05-2018)“…Mammalian circadian rhythms are phase‐adjusted and amplified by external cues such as light and food. While the light input pathway via the central clock, the…”
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Reassessment of Internal Thyroid Doses to 1,080 Children Examined in a Screening Survey after the 2011 Fukushima Nuclear Disaster
Published in Health physics (1958) (01-01-2020)“…ABSTRACTThe dose reconstruction of populations potentially affected by the accident at the Fukushima Daiichi nuclear power plant in March 2011 is of great…”
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Estimation methods for human circadian phase by use of peripheral tissues
Published in Hypertension research (01-09-2016)“…Almost all living organisms, including humans, exhibit diurnal rhythms of physiology and behavior, which are driven by the circadian clock. Many studies have…”
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In vivo evaluation of the effect of lithium on peripheral circadian clocks by real-time monitoring of clock gene expression in near-freely moving mice
Published in Scientific reports (29-07-2019)“…Lithium has been used as a mood stabilizer to treat human bipolar disorders for over half a century. Several studies have suggested the possibility that the…”
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Lessons Learned from the Accident at the Fukushima Dai-ichi Nuclear Power Plant-More than Basic Knowledge: Education and its Effects Improve the Preparedness and Response to Radiation Emergency
Published in Radiation protection dosimetry (01-09-2016)“…A huge earthquake struck the northeast coast of the main island of Japan on 11 March 2011 triggering an extremely large tsunami to hit the area. The earthquake…”
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12
Effects of the chelating agent DTPA on naturally accumulating metals in the body
Published in Toxicology letters (10-10-2021)“…Diethylenetriaminepentaacetate (DTPA) is the most widely used chelating agent for Pu and Am. Volunteers were assigned to receive intravenous injections or…”
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Potential negative effect of total parenteral nutrition on the human circadian clock
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-10-2022)“…When patients cannot eat on their own, total parenteral nutrition (TPN) is a clinically beneficial method of maintaining nutrition. However, many animal…”
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A simple method using ex vivo culture of hair follicle tissue to investigate intrinsic circadian characteristics in humans
Published in Scientific reports (28-07-2017)“…Almost all organisms maintain a circadian clock from birth to death to synchronize their own physiology and behavior with the earth’s rotation. Because the in…”
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The role of cell-autonomous circadian oscillation of Cry transcription in circadian rhythm generation
Published in Cell reports (Cambridge) (19-04-2022)“…The current model of the mammalian circadian clock describes cell-autonomous and negative feedback-driven circadian oscillation of Cry and Per transcription as…”
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Noninvasive method for assessing the human circadian clock using hair follicle cells
Published in Proceedings of the National Academy of Sciences - PNAS (31-08-2010)“…A thorough understanding of the circadian clock requires qualitative evaluation of circadian clock gene expression. Thus far, no simple and effective method…”
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Detection of endogenous circadian rhythms of clock gene mRNA expression in mouse lung tissue using slice cultures
Published in STAR protocols (16-06-2023)“…Detection of endogenous circadian rhythms in clock gene mRNA expression requires that mice be sacrificed at regular time intervals over one or more days. This…”
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Effect of different light–dark schedules on estrous cycle in mice, and implications for mitigating the adverse impact of night work
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-10-2017)“…Approximately 20% of workers in developed countries are involved in night work. Nevertheless, many studies have strongly suggested that night‐work‐induced…”
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Compensation for intracellular environment in expression levels of mammalian circadian clock genes
Published in Scientific reports (07-02-2014)“…The circadian clock is driven by transcriptional oscillation of clock genes in almost all body cells. To investigate the effect of cell type-specific…”
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Metabolic state switches between morning and evening in association with circadian clock in people without diabetes
Published in Journal of diabetes investigation (01-09-2022)“…Aims/Introduction Understanding morning–evening variation in metabolic state is critical for managing metabolic disorders. We aimed to characterize this…”
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