Search Results - "AKARD, L. P"

Bosutinib for pretreated patients with chronic phase chronic myeloid leukemia: primary results of the phase 4 BYOND study by Hochhaus, Andreas, Gambacorti-Passerini, Carlo, Abboud, Camille, Gjertsen, Bjørn Tore, Brümmendorf, Tim H., Smith, B. Douglas, Ernst, Thomas, Giraldo-Castellano, Pilar, Olsson-Strömberg, Ulla, Saussele, Susanne, Bardy-Bouxin, Nathalie, Viqueira, Andrea, Leip, Eric, Russell-Smith, T. Alexander, Leone, Jocelyn, Rosti, Gianantonio, Watts, Justin, Giles, Francis J.

“…Bosutinib is approved for newly diagnosed Philadelphia chromosome-positive (Ph+) chronic phase (CP) chronic myeloid leukemia (CML) and for Ph+ CP, accelerated…”
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Slow platelet recovery after PBPC transplantation from unrelated donors by Jansen, J, Hanks, S G, Akard, L P, Morgan, J A, Nolan, P L, Dugan, M J, Reeves, M I, Thompson, J M

“…The effects of the composition of PBPC grafts from matched related donors (MRDs) and matched unrelated donors (MUDs) have not been compared. In a single-center…”
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Longitudinal Study of Adaptation to the Stress of Bone Marrow Transplantation by FIFE, B. L, HUSTER, G. A, CORNETTA, K. G, KENNEDY, V. N, AKARD, L. P, BROUN, E. R

“…This prospective longitudinal study of adaptation to bone marrow transplantation (BMT) addressed three questions: (1) When during BMT do individuals experience…”
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Regulation of neutrophil NADPH oxidase activation in a cell-free system by guanine nucleotides and fluoride. Evidence for participation of a pertussis and cholera toxin-insensitive G protein by Gabig, T G, English, D, Akard, L P, Schell, M J

“…Guanine nucleotide-binding regulatory proteins (G proteins) transduce a remarkably diverse group of extracellular signals to a relatively limited number of…”
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Hematopoietic growth factor after autologous peripheral blood transplantation : Comparison of G-CSF and GM-CSF by JANSEN, J, THOMPSON, E. M, HANKS, S, GREENSPAN, A. R, THOMPSON, J. M, DUGAN, M. J, AKARD, L. P

“…Autologous peripheral blood stem cell (PBSC) transplantation results in rapid hematologic recovery when sufficient numbers of CD34+ cells/kg are infused…”
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Rapid Deactivation of NADPH Oxidase in Neutrophils: Continuous Replacement by Newly Activated Enzyme Sustains the Respiratory Burst by Akard, Luke P., English, Denis, Gabig, Theodore G.

“…The cell-free system for activation of the neutrophil NADPH oxidase allowed us to examine activation of the oxidase in the absence of its NADPH-dependent…”
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Semiautomated processing of bone marrow grafts for transplantation by English, D, Lamberson, R, Graves, V, Akard, L P, McCarthy, L J, Jansen, J

“…This report describes experience with a technique for the isolation of mononuclear cells from large quantities of human bone marrow using a blood cell…”
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Successful allogeneic bone marrow transplantation in an adult with aplastic anemia following orthotopic liver transplantation for non-A, non-B, non-C hepatitis by Dugan, M J, Rouch, D A, Akard, L P, Sperl, B G, Black, J R, Markham, Jr, R E, Jansen, J

“…A 29-year-old male patient presented with acute liver failure from non-A, non-B and non-C hepatitis, necessitating orthotopic liver transplantation. After…”
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Immunomagnetic CD4+ and CD8+ cell depletion for patients at high risk for severe acute GVHD by Jansen, J, Hanks, S, Akard, L P, Thompson, J M, Burns, S, Chang, Q, English, D, Garrett, P

“…Acute GVHD remains a major problem in allogeneic BMT, in particular when donors other than HLA-identical siblings are used. To determine the efficacy of an…”
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Cytosolic inactivation of translocated neutrophil plasma membrane protein tyrosine phosphatase by CUI, Y, HARVEY, K. A, SIDDIQUI, R. A, JANSEN, J, AKARD, L. P, THOMPSON, J. M, GARCIA, J. G. N, ENGLISH, D

“…Phosphotyrosine phosphatases (PTPases) regulate cellular metabolic activation by reversing the effects of tyrosine kinases activated earlier in intracellular…”
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Alpha-interferon and immune hemolytic anemia by Akard, L P, Hoffman, R, Elias, L, Saiers, J H

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Growth factor induction of cytosolic protein tyrosine kinase activity in human haemopoietic progenitor cells isolated by flow cytometry by Harvey, K A, Siddiqui, R A, Jansen, J, Akard, L P, Thompson, J M, Cui, Y, Chang, Q, English, D

“…We employed a highly sensitive method to assay protein tyrosine kinase activity in extracts of subpopulations of CD34+ bone marrow progenitor cells isolated by…”
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Temporal adaptation of neutrophil oxidative responsiveness to n-formyl- methionyl-leucyl-phenylalanine. Acceleration by granulocyte-macrophage colony stimulating factor by English, D, Broxmeyer, HE, Gabig, TG, Akard, LP, Williams, DE, Hoffman, R

“…This investigation was undertaken to clarify the mechanism by which purified recombinant human granulocyte-macrophage colony stimulating factor (GM-CSF)…”
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Chronic T cell lymphoproliferative disorder and pure red cell aplasia. Further characterization of cell-mediated inhibition of erythropoiesis and clinical response to cytotoxic chemotherapy by Akard, L P, Brandt, J, Lu, L, Jansen, J, Hoffman, R

“…Two patients with pure red cell aplasia and a T cell lymphoproliferative disorder were studied in order to define the mechanism of suppression of…”
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Impaired PBPC collection in patients with myeloma after high-dose melphalan by Jansen, J., Thompson, J.M., Dugan, M.J., Wiemann, M.C., Hanks, S., Greenspan, A.R., Akard, L.P.

“…Tandem stem cell transplantation is an important treatment option for patients with myeloma and some additional tumors. In an attempt to reduce the…”
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Cell-free activation of phagocyte NADPH-oxidase: tissue and differentiation-specific expression of cytosolic cofactor activity by Parkinson, J F, Akard, L P, Schell, M J, Gabig, T G

“…We examined a variety of tissues for the presence of cytosolic cofactor activity that would support arachidonate-dependent cell-free activation of…”
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Chemotactic Migration Triggers IL-8 Generation in Neutrophilic Leukocytes by Siddiqui, Rafat A, Akard, Luke P, Garcia, J. G. N, Cui, Yi, English, Denis

“…Neutrophils recovered from inflammatory exudates possess increased levels of IL-8, but exposure of neutrophils to chemoattractants results in only a modest…”
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Characterization and purification of neutrophil ecto-phosphatidic acid phosphohydrolase by English, D, Martin, M, Harvey, K A, Akard, L P, Allen, R, Widlanski, T S, Garcia, J G, Siddiqui, R A

“…Phosphatidic acid and its derivatives play potentially important roles as extracellular messengers in biological systems. An ecto-phosphatidic acid…”
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Rapid deactivation of NADPH oxidase in neutrophils: continuous replacement by newly activated enzyme sustains the respiratory burst by Akard, LP, English, D, Gabig, TG

“…The cell-free system for activation of the neutrophil NADPH oxidase allowed us to examine activation of the oxidase in the absence of its NADPH-dependent…”
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Open-label study evaluating change in chronic low-grade (LG) non-hematologic (heme) adverse events (AEs) in Philadelphia positive (Ph+) CML-CP patients (pts) switched from imatinib (IM) to nilotinib (NL) by Cortes, J. E., Miller, C. B., Lipton, J. H., Busque, L., Akard, L. P., Pinilla-Ibarz, J., Ericson, S., Mauro, M. J.

“…Abstract only…”
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