Search Results - "AKAMINE, Eliana H"

Toll-like receptor 4 contributes to blood pressure regulation and vascular contraction in spontaneously hypertensive rats by Bomfim, Gisele F, Dos Santos, Rosangela A, Oliveira, Maria Aparecida, Giachini, Fernanda R, Akamine, Eliana H, Tostes, Rita C, Fortes, Zuleica B, Webb, R Clinton, Carvalho, Maria Helena C

“…Activation of TLRs (Toll-like receptors) induces gene expression of proteins involved in the immune system response. TLR4 has been implicated in the…”
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Gold nanoparticles reduce inflammation in cerebral microvessels of mice with sepsis by Di Bella, Davide, Ferreira, João P S, Silva, Renee de Nazare O, Echem, Cinthya, Milan, Aline, Akamine, Eliana H, Carvalho, Maria H, Rodrigues, Stephen F

“…Sepsis is an emergency medical condition that can lead to death and it is defined as a life-threatening organ dysfunction caused by immune dysregulation in…”
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Angiotensin‐(1‐7) prevents T3‐induced cardiomyocyte hypertrophy by upregulating FOXO3/SOD1/catalase and downregulating NF‐ĸB by Senger, Nathalia, Parletta, Aline, Marques, Bruno V. D., Akamine, Eliana H., Diniz, Gabriela P., Campagnole‐Santos, Maria J., Santos, Robson A. S., Barreto‐Chaves, Maria Luiza M.

“…Clinical studies have shown a correlation between thyroid disorders and cardiac diseases. High levels of triiodothyronine (T3) induce cardiac hypertrophy, a…”
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Oxidative stress and inflammatory mediators contribute to endothelial dysfunction in high-fat diet-induced obesity in mice by KOBAYASI, Renata, AKAMINE, Eliana H, DAVEL, Ana P, RODRIGUES, Maria A. M, CARVALHO, Carla R. O, ROSSONI, Luciana V

“…We investigated the effects of high-fat diet-induced obesity on vascular proinflammatory factors and oxidative stress on endothelium-dependent relaxation of…”
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Intrauterine growth restriction leads to a high-corticosterone producing offspring: An implication for pulmonary infection susceptibility by Gil, Noemi L., Azevedo, Gabriela A., Balbino, Aleksandro M., Silva, Marina M., Carvalho, Maria Helena C., Akamine, Eliana H., Keller, Alexandre C., Landgraf, Richardt G., Landgraf, Maristella A.

“…Although intrauterine growth restriction (IUGR) impairs immune system homeostasis and lung development, its relationship with the susceptibility to pulmonary…”
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Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular Senescence by Barros, Paula R., Costa, Tiago J., Akamine, Eliana H., Tostes, Rita C.

“…Increasing scientific interest has been directed to sex as a biological and decisive factor on several diseases. Several different mechanisms orchestrate…”
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Obesity induced by high-fat diet promotes insulin resistance in the ovary by Akamine, Eliana H, Marçal, Anderson C, Camporez, João Paulo, Hoshida, Mara S, Caperuto, Luciana C, Bevilacqua, Estela, Carvalho, Carla R O

“…Besides the effects on peripheral energy homeostasis, insulin also has an important role in ovarian function. Obesity has a negative effect on fertility, and…”
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An interaction of renin-angiotensin and kallikrein-kinin systems contributes to vascular hypertrophy in angiotensin II-induced hypertension: in vivo and in vitro studies by Ceravolo, Graziela S, Montezano, Augusto C, Jordão, Maria T, Akamine, Eliana H, Costa, Tiago J, Takano, Ana P, Fernandes, Denise C, Barreto-Chaves, Maria L, Laurindo, Francisco R, Tostes, Rita C, Fortes, Zuleica B, Chopard, Renato P, Touyz, Rhian M, Carvalho, Maria Helena C

“…The kallikrein-kinin and renin-angiotensin systems interact at multiple levels. In the present study, we tested the hypothesis that the B1 kinin receptor (B1R)…”
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Detrimental Effects of Testosterone Addition to Estrogen Therapy Involve Cytochrome P-450-Induced 20-HETE Synthesis in Aorta of Ovariectomized Spontaneously Hypertensive Rat (SHR), a Model of Postmenopausal Hypertension by Costa, Tiago J, Ceravolo, Graziela S, Echem, Cinthya, Hashimoto, Carolina M, Costa, Beatriz P, Santos-Eichler, Rosangela A, Oliveira, Maria Aparecida, Jiménez-Altayó, Francesc, Akamine, Eliana H, Dantas, Ana Paula, Carvalho, Maria Helena C

“…Postmenopausal period has been associated to different symptoms such as hot flashes, vulvovaginal atrophy, hypoactive sexual desire disorder (HSDD) and others…”
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Upregulation of ERK1/2-eNOS via AT2 receptors decreases the contractile response to angiotensin II in resistance mesenteric arteries from obese rats by Hagihara, Graziela N, Lobato, Nubia S, Filgueira, Fernando P, Akamine, Eliana H, Aragão, Danielle S, Casarini, Dulce E, Carvalho, Maria Helena C, Fortes, Zuleica B

“…It has been clearly established that mitogen-activated protein kinases (MAPKS) are important mediators of angiotensin II (Ang II) signaling via AT1 receptors…”
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P8 O-GlcNAcylation Increases Constriction in Common Carotid Artery of Senescent-Accelerated Female Mice by Costa, Tiago J., Silva, Josiane F., da Silva, Renée de Nazaré O., Barros, Paula R., Bolsoni, Juliana, Rodrigues, Daniel, Akamine, Eliana H., Tostes, Rita

“…The glycosylation with O -linked- N -acetylglucosamine ( O -GlcNAc) is an enzymatic process found on nuclear and cytoplasmic proteins. Augmented levels of O…”
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Long-term effects of intrauterine malnutrition on vascular function in female offspring: Implications of oxidative stress by Franco, Maria C.P., Akamine, Eliana H., Rebouças, Nancy, Carvalho, Maria Helena C., Tostes, Rita C.A., Nigro, Dorothy, Fortes, Zuleica B.

“…Maternal malnutrition is known to impair fetal growth and predispose to the development of hypertension and type 2 diabetes. Recently, studies have…”
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Toll-Like Receptors Represent an Important Link for Sex Differences in Cardiovascular Aging and Diseases by Echem, Cinthya, Akamine, Eliana H.

“…Human life span expectancy has increased, and aging affects the organism in several ways, leading, for example, to an increased risk of cardiovascular…”
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H2O2 generated from mitochondrial electron transport chain in thoracic perivascular adipose tissue is crucial for modulation of vascular smooth muscle contraction by Costa, Rafael M., Filgueira, Fernando P., Tostes, Rita C., Carvalho, Maria Helena C., Akamine, Eliana H., Lobato, Nubia S.

“…The perivascular adipose tissue (PVAT) releases a variety of factors that affect vascular function. PVAT in the thoracic aorta shares characteristics with the…”
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Carotid dysfunction in senescent female mice is mediated by increased α 1A -adrenoceptor activity and COX-derived vasoconstrictor prostanoids by Costa, Tiago J, Barros, Paula R, Duarte, Diego A, Silva-Neto, Júlio A, Hott, Sara Cristina, Santos-Silva, Thamyris, Costa-Neto, Claudio M, Gomes, Felipe V, Akamine, Eliana H, McCarthy, Cameron G, Jimenez-Altayó, Francesc, Dantas, Ana Paula, Tostes, Rita C

“…α-Adrenergic receptors are crucial regulators of vascular hemodynamics and essential pharmacological targets for cardiovascular diseases. With aging, there is…”
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Vascular dysfunction programmed in male rats by topiramate during peripubertal period by Moura, Kawane F., Silva, Deborah Gomes da, Vidigal, Camila Borecki, Silva, Gabriel Smolak Sobieski e, Pinto, Ingrid Caroline, Simão, Andréa Name Colado, Marques, Bruno V.D., Andrade, Fábio Goulart de, Casagrande, Rúbia, Gerardin, Daniela C.C., Akamine, Eliana H., Franco, Maria do Carmo P., Ceravolo, Graziela S.

“…The present study evaluated whether topiramate (TPM) treatment during the peripubertal period affects vascular parameters of male rats and whether oxidative…”
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Tetrahydrobiopterin improves endothelial dysfunction and vascular oxidative stress in microvessels of intrauterine undernourished rats by Franco, Maria do Carmo P., Fortes, Zuleica B., Akamine, Eliana H., Kawamoto, Elisa M., Scavone, Cristoforo, De Britto, Luiz Roberto Giorgetti, Muscara, Marcelo N., Teixeira, Simone A., Tostes, Rita C. A., Carvalho, Maria Helena C., Nigro, Dorothy

“…In the present study, we investigated the effects of the exogenous application of tetrahydrobiopterin on the endothelium-dependent vasorelaxation and…”
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Association of testosterone with estrogen abolishes the beneficial effects of estrogen treatment by increasing ROS generation in aorta endothelial cells by Costa, Tiago J, Ceravolo, Graziela S, dos Santos, Rosangela A, de Oliveira, Maria Aparecida, Araújo, Priscila X, Giaquinto, Luciana R, Tostes, Rita C, Akamine, Eliana H, Fortes, Zuleica B, Dantas, Ana Paula, Carvalho, Maria Helena C

“…Testosterone has been added to hormone replacement therapy to treat sexual dysfunction in postmenopausal women. Whereas estrogen has been associated with…”
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Intrauterine exposure to metformin: Evaluation of endothelial and perivascular adipose tissue function in abdominal aorta of adult offspring by Vidigal, Camila B., Novi, Daniella R.B.S., Moura, Kawane F., Picinin, Rafaela, Montagnini, Bruno G., Silva, Renée de N. O. da, da Silva, Matheus D.V., de Andrade, Fábio G., Akamine, Eliana H., Gerardin, Daniela C.C., Ceravolo, Graziela S.

“…The biguanide metformin (MET) has been used during pregnancy for treatment of polycystic ovary syndrome and gestational diabetes. MET crosses the placenta and…”
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Minalrestat, an aldose reductase inhibitor, corrects the impaired microvascular reactivity in diabetes by Akamine, Eliana H, Hohman, Thomas C, Nigro, Dorothy, Carvalho, Maria Helena C, de Cássia Tostes, Rita, Fortes, Zuleica B

“…We demonstrated that aldose reductase inhibition corrects the impaired microvascular responses to inflammatory mediators in diabetic rats. To study the…”
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