Search Results - "AJARIM, Dahish"

Weekly Paclitaxel given concurrently with Durvalumab has a favorable safety profile in triple-negative metastatic breast cancer by Ghebeh, Hazem, Al-Sayed, Adher, Eiada, Riham, Cabangon, Leilani, Ajarim, Dahish, Suleman, Kausar, Tulbah, Asma, Al-Tweigeri, Taher

“…Therapeutic anti-PD-L1 antibodies are safe as a monotherapy, albeit with minimal efficacy in triple-negative breast cancer (TNBC). This trial aimed to test the…”
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Fascin is a key regulator of breast cancer invasion that acts via the modification of metastasis-associated molecules by Al-Alwan, Monther, Olabi, Safiah, Ghebeh, Hazem, Barhoush, Eman, Tulbah, Asma, Al-Tweigeri, Taher, Ajarim, Dahish, Adra, Chaker

“…The actin-bundling protein, fascin, is a member of the cytoskeletal protein family that has restricted expression in specialized normal cells. However, many…”
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Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women by Colak, Dilek, Nofal, Asmaa, Albakheet, Albandary, Nirmal, Maimoona, Jeprel, Hatim, Eldali, Abdelmoneim, Al-Tweigeri, Taher, Tulbah, Asma, Ajarim, Dahish, Malik, Osama Al, Inan, Mehmet S, Kaya, Namik, Park, Ben H, Bin Amer, Suad M

“…Breast cancer in young women is more aggressive with a poorer prognosis and overall survival compared to older women diagnosed with the disease. Despite recent…”
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PALB2 germline mutations in a large cohort of Middle Eastern breast-ovarian cancer patients by Siraj, Abdul K., Bu, Rong, Parvathareddy, Sandeep Kumar, Iqbal, Kaleem, Azam, Saud, Qadri, Zeeshan, Al-Rasheed, Maha, Haqawi, Wael, Diaz, Mark, Victoria, Ingrid G., Al-Badawi, Ismail A., Tulbah, Asma, Al-Dayel, Fouad, Ajarim, Dahish, Al-Kuraya, Khawla S.

“…The PALB2 gene is a breast cancer (BC) and ovarian cancer (OC) predisposition gene involved in the homologous recombination repair pathway. However, the…”
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The B7-H1 (PD-L1) T Lymphocyte-Inhibitory Molecule Is Expressed in Breast Cancer Patients with Infiltrating Ductal Carcinoma: Correlation with Important High-Risk Prognostic Factors by Ghebeh, Hazem, Mohammed, Shamayel, Al-Omair, Abeer, Qattant, Amal, Lehe, Cynthia, Al-Qudaihi, Ghofran, Elkum, Naser, Alshabanah, Mohamed, Bin Amer, Suad, Tulbah, Asma, Ajarim, Dahish, Al-Tweigeri, Taher, Dermime, Said

“…B7-H1 molecule increases the apoptosis of tumorreactive T lymphocytes and reduces their immunogenicity. Breast cancer is the second most common cause of…”
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XIAP over-expression is an independent poor prognostic marker in Middle Eastern breast cancer and can be targeted to induce efficient apoptosis by Hussain, Azhar R, Siraj, Abdul Khalid, Ahmed, Maqbool, Bu, Rong, Pratheeshkumar, Poyil, Alrashed, Alanood M, Qadri, Zeeshan, Ajarim, Dahish, Al-Dayel, Fouad, Beg, Shaham, Al-Kuraya, Khawla S

“…Breast cancer is the most common cancer in females and is ranked second in cancer-related deaths all over the world in women. Despite improvement in diagnosis,…”
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ALK alteration is a frequent event in aggressive breast cancers by Siraj, Abdul K, Beg, Shaham, Jehan, Zeenath, Prabhakaran, Sarita, Ahmed, Maqbool, R Hussain, Azhar, Al-Dayel, Fouad, Tulbah, Asma, Ajarim, Dahish, Al-Kuraya, Khawla S

“…Breast cancer is the most common female malignancy worldwide and, despite improvements in treatment modalities, there are increased chances of recurrence and…”
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Successful Recovery of COVID-19 Associated With Cardiomyopathy in Advanced Breast Cancer Patient With Pulmonary Lymphangitis Carcinomatosis by Alquaydheb, Hisham, Alharbi, Abrar, Badran, Ahmed, Alshamsan, Bader, Algwaiz, Ghada, Elshenawy, Mahmoud A, Ajarim, Dahish

“…SARS-CoV-2 infection induces myocardiopathy in 19% of severe cases, with a mortality rate of up to 51%. The mainstay of treatment is supportive care, steroids,…”
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Gemcitabine-Induced Myositis in a Luminal B Breast Cancer patient: A Case Report by Badran, Ahmed, Ali, Saad Salman, Arabi, Tarek Ziad, Hinkston, Abdullaah Khaleel, Shaik, Abdullah, Elshenawy, Mahmoud A, Ajarim, Dahish

“…Human epidermal growth factor receptor-positive breast cancer is an aggressive cancer which represents approximately a quarter of all breast cancers worldwide…”
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Single-Institute Review of HER-2/Neu-Positive Invasive Lobular Breast Carcinoma in an Arab Population by Osmani, Asif Husain, Tulbah, Asma M, AlSayed, Adher, AlShanqeeti, Ali, Al-Twegieri, Taher, Ajarim, Dahish S, Suleman, Kausar

“…BACKGROUND Invasive lobular carcinoma is special subtype of breast cancer that has clinical behavior and morphology distinct from other breast cancer subtypes…”
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Prevalence of germline TP53 mutation among early onset middle eastern breast cancer patients by Siraj, Abdul Khalid, Masoodi, Tariq, Bu, Rong, Parvathareddy, Sandeep Kumar, Iqbal, Kaleem, Azam, Saud, Al-Rasheed, Maha, Ajarim, Dahish, Tulbah, Asma, Al-Dayel, Fouad, Al-Kuraya, Khawla Sami

“…The data on prevalence and clinical relevance of TP53 germline mutations in early onset Middle-Eastern breast cancer (BC) is limited. We determined TP53…”
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PD-L1 Protein Expression in Middle Eastern Breast Cancer Predicts Favorable Outcome in Triple-Negative Breast Cancer by Parvathareddy, Sandeep Kumar, Siraj, Abdul K, Ahmed, Saeeda O, Ghazwani, Laila Omar, Aldughaither, Saud M, Al-Dayel, Fouad, Tulbah, Asma, Ajarim, Dahish, Al-Kuraya, Khawla S

“…Programmed cell-death ligand 1 (PD-L1) has been shown to induce potent T-cell mediated anti-tumoral immunity. The significance of PD-L1 expression in the…”
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Being 40 or younger is an independent risk factor for relapse in operable breast cancer patients: the Saudi Arabia experience by Elkum, Naser, Dermime, Said, Ajarim, Dahish, Al-Zahrani, Ali, Alsayed, Adher, Tulbah, Asma, Al Malik, Osama, Alshabanah, Mohamed, Ezzat, Adnan, Al-Tweigeri, Taher

“…Breast cancer in young Saudi women is a crucial problem. According to the 2002 annual report of Saudi National Cancer Registry, breast cancers that developed…”
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Clinico-pathological pattern of extranodal non-Hodgkin's lymphoma in Saudi Arabia by Al Diab, Abdul Rahman, Aleem, Aamer, Qayum, Abdul, Al Askar, Ahmed S, Ajarim, Dahish S

“…The incidence of primary extranodal non-Hodgkin's lymphoma (NHL) is variable in different regions of world but there is a paucity of literature on various…”
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Prospective phase II study of neoadjuvant doxorubicin followed by cisplatin/docetaxel in locally advanced breast cancer by Al-Tweigeri, Taher A., Ajarim, Dahish S., Alsayed, Adher A., Rahal, Mohamed M., Alshabanah, Mohamed O., Tulbah, Asma M., Al-Malik, Osama A., Fatani, Doha M., El-Husseiny, Gamal A., Elkum, Naser B., Ezzat, Adnan A.

“…The objective of this study is to evaluate the efficacy and safety profile of the doxorubicin followed by cisplatin/docetaxel as primary chemotherapy for…”
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Localized non-Hodgkin's lymphoma of Waldeyer's ring: Clinical features, management, and prognosis of 130 adult patients by Ezzat, Adnan A., Ibrahim, Ezzeldin M., El Weshi, Amr N., Khafaga, Yasser M., AlJurf, Mahmoud, Martin, Justin M., Ajarim, Dahish S., Bazarbashi, Shouki N., Stuart, Robert K., Zucca, Emanuele

“…Background Waldeyer's ring (WR) is the primary site of non‐Hodgkin's lymphoma (NHL) involvement in approximately 5% to 10% of all lymphoma patients, and it…”
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Adjuvant chemotherapy in 780 patients with early breast cancer: 10-year data from Saudi Arabia by Ibrahim, Ezzeldin M, Ezzat, Adnan A, Rahal, Mohammed M, Raja, Madras M, Ajarim, Dahish S

“…By and large, data about adjuvant chemotherapy for breast cancer in the Middle East are lacking. Retrospective analysis of prospectively captured data from a…”
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Efficacy and toxicity of trastuzumab emtansine among patients with HER-2-positive metastatic breast cancer in Saudi Arabia by Badran, Ahmed Ali, Fallatah, Waleed, Hinkston, Abdullaah Khaleel, Arabi, Tarek, Algwaiz, Ghada, Elshenawy, Mahmoud Abdelsatar, Elshentenawy, Ayman, Haque, Emaan Ul, Twegieri, Taher, Akhtar, Saad, Alsayed, Adher, Ajarim, Dahish Saed, Alzahrani, Meshari, Alaklabi, Sabah, Elhassan, Tusneem, Suleman, Kausar

“…e13001 Background: Trastuzumab emtansine (T-DM1) significantly prolongs progression-free survival (PFS) with a safe drug profile in advanced HER-2-positive…”
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Does the Timing of Surgery after Neoadjuvant Therapy in Breast Cancer Patients Affect the Outcome? by Suleman, Kausar, Almalik, Osama, Haque, Emaan, Mushtaq, Ali, Badran, Ahmed, Alsayed, Adher, Ajarim, Dahish, Al-Tweigeri, Taher, Jastaniyah, Noha, Elhassan, Tusneem, Alkhayal, Wafa

“…There is a paucity of literature examining the impact of timing of surgery after neoadjuvant chemotherapy. This study aimed to analyze the impact of the time…”
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Metaplastic breast cancer: Disease characteristics and outcome in Arab women by Alsayed, Adher, Alshamsan, Bader I, Alshibany, Aisha, Elshenawy, Mahmoud Abdelsatar, Badran, Ahmed ali, Al-Tweigeri, Taher, Ajarim, Dahish Saed, Suleman, Kausar

“…Abstract only e12534 Background: Metaplastic breast cancer (MPBC) accounts for less than 1% of all breast cancer subtypes. Methods: Patients diagnosed with…”
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