Search Results - "AIMI, Norio"
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Selenosugars Are Key and Urinary Metabolites for Selenium Excretion within the Required to Low-Toxic Range
Published in Proceedings of the National Academy of Sciences - PNAS (10-12-2002)“…Essential micronutrient selenium is excreted into the urine and/or expired after being transformed to methylated metabolites. Monomethylated selenium is…”
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Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa
Published in Life sciences (1973) (12-03-2004)“…Mitragynine is an indole alkaloid isolated from the Thai medicinal plant Mitragyna speciosa. We previously reported the morphine-like action of mitragynine and…”
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Camptothecin biosynthetic genes in hairy roots of Ophiorrhiza pumila: Cloning, characterization and differential expression in tissues and by stress compounds
Published in Plant and cell physiology (01-04-2003)“…Camptothecin derivatives are clinically used antitumor compounds that biogenetically belong to a group of monoterpenoid indole alkaloids (TIA). We have already…”
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New type of trimeric and pentameric indole alkaloids from Psychotria rostrata
Published in Organic letters (19-08-2004)“…Two new tryptamine-related alkaloids, psychotrimine and psychopentamine, were isolated from the leaves of Psychotria rostrata, and their novel structures were…”
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Studies on the Synthesis and Opioid Agonistic Activities of Mitragynine-Related Indole Alkaloids: Discovery of Opioid Agonists Structurally Different from Other Opioid Ligands
Published in Journal of medicinal chemistry (25-04-2002)“…Mitragynine (1) is a major alkaloidal component in the Thai traditional medicinal herb, Mitragyna speciosa, and has been proven to exhibit analgesic activity…”
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Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa
Published in Life sciences (1973) (19-11-2005)“…7-Hydroxymitragynine is a potent opioid analgesic alkaloid isolated from the Thai medicinal herb Mitragyna speciosa. In the present study, we investigated the…”
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Rhynchophylline and isorhynchophylline inhibit NMDA receptors expressed in Xenopus oocytes
Published in European journal of pharmacology (22-11-2002)“…Rhynchophylline and isorhynchophylline are major tetracyclic oxindole alkaloid components of Uncaira species, which have been long used as medicinal plants. In…”
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Biosynthesis of Camptothecin. In Silico and in vivo Tracer Study from [1-13C]Glucose
Published in Plant physiology (Bethesda) (01-01-2004)“…Camptothecin derivatives are clinically used antitumor alkaloids that belong to monoterpenoid indole alkaloids. In this study, we investigated the biosynthetic…”
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Metabolite profiling of alkaloids and strictosidine synthase activity in camptothecin producing plants
Published in Phytochemistry (Oxford) (01-02-2003)“…Camptothecin derivatives are clinically used anti-neoplastic alkaloids that biogenetically belong to monoterpenoid indole alkaloids. Camptothecin-related…”
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Camptothecins and Two New Monoterpene Glucosides from Ophiorrhiza liukiuensis
Published in Chemical & Pharmaceutical Bulletin (01-10-2005)“…Two new monoterpene glucosides, demethylsecologanol and 3′′′-O-glucosylsenburiside II, were isolated from Ophiorrhiza liukiuensis (Rubiaceae) together with 23…”
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Isolation, structure elucidation, and total synthesis of two new Chimonanthus alkaloids, chimonamidine and chimonanthidine
Published in Tetrahedron (01-01-2004)“…Two new tryptamine-related alkaloids, chimonamidine and chimonanthidine, were isolated from the seeds of Chimonanthus praecox Link. and their structures…”
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A new prenylated dihydrochalcone from the leaves of Artocarpus lowii
Published in Journal of natural medicines (01-07-2008)“…A new prenylated dihydrochalcone, 2′,4′-dihydroxy-4-methoxy-3′-prenyldihydrochalcone ( 1 ), along with two known compounds,…”
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Unique Coordination Mode of Potassium Ions to Glycyrrhizin: X-ray Crystal Structure of Glycyrrhizin Dipotassium Salt
Published in Chemistry letters (05-11-2009)“…The coordination of six potassium ions to glycyrrhizin (1) is shown in a crystal: two crystallographically independent (K1 and K2) and four symmetry-translated…”
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Antitubercular triterpenes and phytosterols from Pandanus tectorius Soland. var. laevis
Published in Journal of natural medicines (01-04-2008)“…Bioassay-guided chromatographic purification of the antitubercular chloroform extract of Pandanus tectorius Soland. var. laevis leaves afforded a new…”
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Bioreactor production of camptothecin by hairy root cultures of Ophiorrhiza pumila
Published in Biotechnology letters (01-03-2002)“…A large-scale culture of hairy root of Ophiorrhiza pumila using a modified 3 l bioreactor was established. The hairy roots, incited by infection of…”
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Camptothecin-related alkaloids from hairy roots of Ophiorrhiza pumila
Published in Tetrahedron (04-11-2002)“…Hairy roots of Ophiorrhiza pumila, a rubiaceous camptothecin-producing plant, were obtained. From an investigation of the secondary metabolites, it was found…”
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First asymmetric total synthesis of Us-7 and -8, novel D-seco Corynanthe-type oxindole alkaloids from Uncaria attenuata: structure revision of Us-7 and determination of absolute stereochemistry
Published in Organic letters (07-08-2003)“…[reaction: see text] Starting from (S)-glycidol, the asymmetric total synthesis of novel D-seco Corynanthe-type oxindoles Us-7 and Us-8 was accomplished. The…”
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Ten New Lycopodium Alkaloids Having the Lycopodane Skeleton Isolated from Lycopodium serratum THUNB
Published in Chemical & Pharmaceutical Bulletin (01-10-2003)“…Ten new alkaloids, lycoposerramines-F (1), -G (2), -H (3), -I (4), -J (5), -K (6), -L (7), -M (8), -N (9), and -O (10), having lycopodine-related structures,…”
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