Search Results - "AIDARUS, NASRA"
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HIV delays IFN-α production from human plasmacytoid dendritic cells and is associated with SYK phosphorylation
Published in PloS one (31-05-2012)“…Plasmacytoid dendritic cells (pDC) are the major producers of type I interferons (IFNs) in humans and rapidly produce IFN-α in response to virus exposure…”
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2
Antigen-independent induction of Tim-3 expression on human T cells by the common γ-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on the phosphoinositide 3-kinase pathway
Published in The Journal of immunology (1950) (15-04-2012)“…T cell Ig mucin domain-containing molecule 3 (Tim-3) is a glycoprotein found on the surface of a subset of CD8(+) and Th1 CD4(+) T cells. Elevated expression…”
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3
HERV-K-specific T cells eliminate diverse HIV-1/2 and SIV primary isolates
Published in The Journal of clinical investigation (01-12-2012)“…The genetic diversity of HIV-1 represents a major challenge in vaccine development. In this study, we establish a rationale for eliminating HIV-1-infected…”
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4
In Women’s Eyes: Key Barriers to Women’s Access to HIV Treatment and a Rights-Based Approach to their Sustained Well-Being
Published in Health and human rights (01-12-2017)“…There is rightly a huge global effort to enable women living with HIV to have long productive lives, through treatment access. However, many women living with…”
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Journal Article -
5
Pharmacologic HIV-1 Nef blockade promotes CD8 T cell-mediated elimination of latently HIV-1-infected cells in vitro
Published in JCI insight (07-09-2017)“…Eradication of the HIV-1 latent reservoir represents the current paradigm to developing a cure for AIDS. HIV-1 has evolved multiple mechanisms to evade CD8 T…”
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Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection
Published in The Journal of experimental medicine (16-01-2012)“…The signaling adaptor TNFR-associated factor 1 (TRAF1) is specifically lost from virus-specific CD8 T cells during the chronic phase of infection with HIV in…”
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Process Evaluation of a Hub-and-Spoke Model to Deliver Coordinated Care for Children with Medical Complexity across Ontario: Facilitators, Barriers and Lessons Learned
Published in Healthcare policy (01-08-2021)“…Background: Complex Care for Kids Ontario (CCKO) is a multi-year strategy aimed at expanding a hub-and-spoke model to deliver coordinated care for children…”
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8
In Women’s Eyes: Key Barriers to Women’s Access to HIV Treatment and a Rights-Based Approach to their Sustained Well-Being
Published in Health and human rights (01-12-2017)“…There is rightly a huge global effort to enable women living with HIV to have long productive lives, through treatment access. However, many women living with…”
Get full text
Journal Article -
9
HIV Delays IFN-[alpha] Production from Human Plasmacytoid Dendritic Cells and Is Associated with SYK Phosphorylation
Published in PloS one (31-05-2012)“…Plasmacytoid dendritic cells (pDC) are the major producers of type I interferons (IFNs) in humans and rapidly produce IFN-[alpha] in response to virus…”
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Journal Article -
10
Improvements in Educational Preparedness for Quality and Safety
Published in Journal of nursing regulation (01-07-2013)“…Ongoing assessments of nurses’ preparedness in quality and safety competencies are absent from prelicensure education programs. Yet acquiring knowledge and…”
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