Search Results - "AHUJA, H. G"

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  1. 1

    Phase II study of arsenic trioxide and ascorbic acid for relapsed or refractory lymphoid malignancies: a Wisconsin Oncology Network study by Chang, JE, Voorhees, PM, Kolesar, JM, Ahuja, HG, Sanchez, FA, Rodriguez, GA, Kim, K, Werndli, J, Bailey, HH, Kahl, BS

    Published in Hematological oncology (01-03-2009)
    “…Arsenic trioxide (As2O3) has established clinical activity in acute promyelocytic leukaemia and has pre‐clinical data suggesting activity in lymphoid…”
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  2. 2

    Abnormalities of the retinoblastoma gene in the pathogenesis of acute leukemia by AHUJA, H. G, JAT, P. S, FOTI, A, BAR-ELI, M, CLINE, M. J

    Published in Blood (15-12-1991)
    “…The retinoblastoma-susceptibility (Rb) gene is an antioncogene that is frequently altered in retinoblastomas, sarcomas, and some epithelial tumors. We examined…”
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  3. 3

    The Pattern of Mutational Involvement of RAS Genes in Human Hematologic Malignancies Determined by DNA Amplification and Direct Sequencing by Ahuja, H.G., Foti, A., Bar-Eli, M., Cline, M.J.

    Published in Blood (15-04-1990)
    “…DNA from 161 patients with various forms of hematologic malignancies were investigated for mutations in exons 1 and 2 of the N-RAS. K-RAS and Ha-RAS gene by…”
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  4. 4

    Correlation Between Molecular and Clinical Events in the Evolution of Chronic Myelocytic Leukemia to Blast Crisis by Foti, A., Ahuja, H.G., Allen, S.L, Koduru, P., Schuster, M.W., Schulman, P., Bar-Eli, M., Cline, M.J.

    Published in Blood (01-06-1991)
    “…A patient with typical Philadelphia chromosome (Ph1)-positive chronic myelocytic leukemia (CML) was studied during sequential phases of disease: (1) initial…”
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  5. 5

    The t(11;20)(p15;q11) chromosomal translocation associated with therapy-related myelodysplastic syndrome results in an NUP98-TOP1 fusion by AHUJA, H. G, FELIX, C. A, APLAN, P. D

    Published in Blood (01-11-1999)
    “…The NUP98 gene is involved in 3 distinct chromosomal rearrangements, t(7;11)(p15;p15), t(2;11)(q31;p15), and inv(11)(p15q22); all of these NUP98 rearrangements…”
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  6. 6

    A splicing mutation accounts for the lack of p53 gene expression in a CML blast crisis cell line: a novel mechanism of p53 gene inactivation by Foti, A, Bar-Eli, M, Ahuja, H G, Cline, M J

    Published in British journal of haematology (01-09-1990)
    “…Alterations of the p53 anti-oncogene have recently been found to occur frequently in the blast crisis of chronic myelocytic leukaemia. The p53 gene may be…”
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  7. 7

    t(9;11)(p22;p15) in acute myeloid leukemia results in a fusion between NUP98 and the gene encoding transcriptional coactivators p52 and p75-lens epithelium-derived growth factor (LEDGF) by AHUJA, Harish G, JIANMING HONG, APLAN, Peter D, TCHEUREKDJIAN, Lucene, FORMAN, Stephen J, SLOVAK, Marilyn L

    Published in Cancer research (Chicago, Ill.) (15-11-2000)
    “…A t(9;11)(p22;p15) chromosomal translocation was identified in an adult patient with de novo acute myelogenous leukemia. Fluorescence in situ hybridization and…”
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  8. 8

    NUP98 gene rearrangements and the clonal evolution of chronic myelogenous leukemia by Ahuja, Harish G., Popplewell, Leslie, Tcheurekdjian, Lucene, Slovak, Marilyn L.

    Published in Genes chromosomes & cancer (01-04-2001)
    “…The role of the BCR‐ABL fusion gene in the pathogenesis of the chronic phase of chronic myelogenous leukemia (CML) has been well established. Several…”
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  9. 9

    Variation in the protein coding region of the human p53 gene by Ahuja, H G, Testa, M P, Cline, M J

    Published in Oncogene (01-09-1990)
    “…This report describes a restriction fragment length polymorphism for the enzyme BglII caused by a conserved C to T change at residue 21 of the human p53 gene…”
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  10. 10

    Analysis of Proto-Oncogenes in Acute Myeloid Leukemia: Loss of Heterozygosity for the Ha-ras Gene by Ahuja, H.G., Foti, A., Zhou, D.J., Cline, M.J.

    Published in Blood (15-02-1990)
    “…At least 13 of 34 patients with acute myeloid leukemia (AML) of varying FAB types were heterozygous for a BamHI restriction fragment length polymorphism (RFLP)…”
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  11. 11

    Potential role for DNA topoisomerase II poisons in the generation of t(11;20)(p15;q11) translocations by Ahuja, Harish G., Felix, Carolyn A., Aplan, Peter D.

    Published in Genes chromosomes & cancer (01-10-2000)
    “…Chromosomal aberrations are frequently associated with therapy‐related myelodysplastic syndromes and acute myelogenous leukemia (t‐MDS/AML) and are thought to…”
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