Search Results - "AGRELO, Rubén"

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    SATB1 Defines the Developmental Context for Gene Silencing by Xist in Lymphoma and Embryonic Cells by Agrelo, Ruben, Souabni, Abdallah, Novatchkova, Maria, Haslinger, Christian, Leeb, Martin, Komnenovic, Vukoslav, Kishimoto, Hiroyuki, Gresh, Lionel, Kohwi-Shigematsu, Terumi, Kenner, Lukas, Wutz, Anton

    Published in Developmental cell (01-04-2009)
    “…The noncoding Xist RNA triggers silencing of one of the two female X chromosomes during X inactivation in mammals. Gene silencing by Xist is restricted to a…”
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    Journal Article
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    Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells by Rauschert, Ines, Aldunate, Fabian, Preussner, Jens, Arocena-Sutz, Miguel, Peraza, Vanina, Looso, Mario, Benech, Juan C, Agrelo, Ruben

    Published in PloS one (19-04-2017)
    “…Nuclear lamins support the nuclear envelope and provide anchorage sites for chromatin. They are involved in DNA synthesis, transcription, and replication. It…”
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    Journal Article
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    A novel Werner Syndrome mutation: pharmacological treatment by read-through of nonsense mutations and epigenetic therapies by Agrelo, Ruben, Sutz, Miguel Arocena, Setien, Fernando, Aldunate, Fabian, Esteller, Manel, Da Costa, Valeria, Achenbach, Ricardo

    Published in Epigenetics (01-04-2015)
    “…Werner Syndrome (WS) is a rare inherited disease characterized by premature aging and increased propensity for cancer. Mutations in the WRN gene can be of…”
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    Journal Article
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    Cancer progenitors and epigenetic contexts: An Xisting connection by Agrelo, Ruben, Wutz, Anton

    Published in Epigenetics (16-11-2009)
    “…In mammals, silencing of one of the two X chromosomes is necessary to achieve dosage compensation. The non coding RNA Xist triggers X inactivation. Gene…”
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    Journal Article
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    Cross-Talk between Aging and Cancer by FRAGA, MARIO F., AGRELO, RUBEN, ESTELLER, MANEL

    Published in Annals of the New York Academy of Sciences (01-04-2007)
    “…:  The risk of having cancer increases with age probably because progenitor cells from mature organisms accumulate enough molecular lesions to evade the…”
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    Journal Article
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    Cross-talk between aging and cancer: the epigenetic language by Fraga, Mario F, Agrelo, Ruben, Esteller, Manel

    Published in Annals of the New York Academy of Sciences (01-04-2007)
    “…The risk of having cancer increases with age probably because progenitor cells from mature organisms accumulate enough molecular lesions to evade the…”
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    Journal Article
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    Response: The Diversity of Proteins Linking Xist to Gene Silencing by Wutz, Anton, Agrelo, Ruben

    Published in Developmental cell (16-10-2012)
    “…In this issue, Nechanitzky et al. question the role of SATB proteins in conferring cellular competence to respond to Xist. Here, Wutz and Agrelo respond,…”
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    Journal Article
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    X inactivation and disease by Agrelo, Ruben, Wutz, Anton

    Published in Seminars in cell & developmental biology (01-04-2010)
    “…X inactivation is the mechanism by which mammals adjust the X-linked gene dosage between the sexes. The dosage difference between XX females and XY males is…”
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    ConteXt of change—X inactivation and disease by Agrelo, Ruben, Wutz, Anton

    Published in EMBO molecular medicine (01-01-2010)
    “…Epigenetic regulation is important for stable maintenance of cell identity. For continued function of organs and tissues, illegitimate changes in cell identity…”
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    Journal Article
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    X inactivation and progenitor cancer cells by Agrelo, Ruben

    Published in Cancers (26-04-2011)
    “…In mammals, silencing of one of the two X chromosomes is necessary to achieve dosage compensation. The 17 kb non-coding RNA called Xist triggers X…”
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    Journal Article Book Review
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    A new molecular model of cellular aging based on Werner syndrome by Agrelo, Ruben

    Published in Medical hypotheses (01-01-2007)
    “…Summary In the Hayflick model, a decrease in the number of cells capable of undergoing proliferation constitutes the main criterion of cellular aging and is…”
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    The impact of MECP2 mutations in the expression patterns of Rett syndrome patients by BALLESTAR, Esteban, ROPERO, Santiago, MONROS, Eugenia, ESTELLER, Manel, ALAMINOS, Miguel, ARMSTRONG, Judith, SETIEN, Fernando, AGRELO, Ruben, FRAGA, Mario F, HERRANZ, Michel, AVILA, Sonia, PINEDA, Mercedes

    Published in Human genetics (2005)
    “…Rett syndrome (RTT), the second most common cause of mental retardation in females, has been associated with mutations in MeCP2, the archetypical member of the…”
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