Search Results - "AFENDY, ARIAN"

Nonalcoholic Steatohepatitis Is the Fastest Growing Cause of Hepatocellular Carcinoma in Liver Transplant Candidates by Younossi, Zobair, Stepanova, Maria, Ong, Janus P., Jacobson, Ira M., Bugianesi, Elisabetta, Duseja, Ajay, Eguchi, Yuichiro, Wong, Vincent W., Negro, Francesco, Yilmaz, Yusuf, Romero-Gomez, Manuel, George, Jacob, Ahmed, Aijaz, Wong, Robert, Younossi, Issah, Ziayee, Mariam, Afendy, Arian

“…Although hepatitis B and C have been the main drivers of hepatocellular carcinoma (HCC), nonalcoholic steatohepatitis (NASH) has recently become an important…”
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A Biomarker Panel for Non-alcoholic Steatohepatitis (NASH) and NASH-Related Fibrosis by Younossi, Zobair M., Page, Sandra, Rafiq, Nila, Birerdinc, Aybike, Stepanova, Maria, Hossain, Noreen, Afendy, Arian, Younoszai, Zahra, Goodman, Zachary, Baranova, Ancha

“…Background Patients with biopsy-proven NASH and especially those with fibrosis are at risk for progressive liver disease, emphasizing the clinical importance…”
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Development and validation of a primary sclerosing cholangitis–specific patient‐reported outcomes instrument: The PSC PRO by Younossi, Zobair M., Afendy, Arian, Stepanova, Maria, Racila, Andrei, Nader, Fatema, Gomel, Rachel, Safer, Ricky, Lenderking, William R., Skalicky, Anne, Kleinman, Leah, Myers, Robert P., Subramanian, G. Mani, McHutchison, John G., Levy, Cynthia, Bowlus, Christopher L., Kowdley, Kris, Muir, Andrew J.

“…Primary sclerosing cholangitis (PSC) is a chronic liver disease associated with inflammation and biliary fibrosis that leads to cholangitis, cirrhosis, and…”
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Knowledge-based identification of soluble biomarkers: hepatic fibrosis in NAFLD as an example by Page, Sandra, Birerdinc, Aybike, Estep, Michael, Stepanova, Maria, Afendy, Arian, Petricoin, Emanuel, Younossi, Zobair, Chandhoke, Vikas, Baranova, Ancha

“…The discovery of biomarkers is often performed using high-throughput proteomics-based platforms and is limited to the molecules recognized by a given set of…”
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The impact of IL28B genotype on the gene expression profile of patients with chronic hepatitis C treated with pegylated interferon alpha and ribavirin by Younossi, Zobair M, Birerdinc, Aybike, Estep, Mike, Stepanova, Maria, Afendy, Arian, Baranova, Ancha

“…Recent studies of CH-C patients have demonstrated a strong association between IL28B CC genotype and sustained virologic response (SVR) after PEG-IFN/RBV…”
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Expression of Inflammation-Related Genes Is Altered in Gastric Tissue of Patients with Advanced Stages of NAFLD by Mehta, Rohini, Birerdinc, Aybike, Neupane, Arpan, Shamsaddini, Amirhossein, Afendy, Arian, Elariny, Hazem, Chandhoke, Vikas, Baranova, Ancha, Younossi, Zobair M.

“…Obesity is associated with chronic low-grade inflammation perpetuated by visceral adipose. Other organs, particularly stomach and intestine, may also…”
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The global epidemiology of NAFLD and NASH in patients with type 2 diabetes: A systematic review and meta-analysis by Younossi, Zobair M., Golabi, Pegah, de Avila, Leyla, Paik, James Minhui, Srishord, Manirath, Fukui, Natsu, Qiu, Ying, Burns, Leah, Afendy, Arian, Nader, Fatema

“…[Display omitted] •Prevalence of NAFLD in patients with type 2 diabetes mellitus is more than 2-fold higher than in the general population.•The overall…”
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Independent Predictors of Fibrosis in Patients With Nonalcoholic Fatty Liver Disease by Hossain, Noreen, Afendy, Arian, Stepanova, Maria, Nader, Fatema, Srishord, Manirath, Rafiq, Nila, Goodman, Zachary, Younossi, Zobair

“…Background & Aims Nonalcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease. We investigated factors associated with advanced…”
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Effects of Alcohol Consumption and Metabolic Syndrome on Mortality in Patients With Nonalcoholic and Alcohol-Related Fatty Liver Disease by Younossi, Zobair M., Stepanova, Maria, Ong, Janus, Yilmaz, Yusuf, Duseja, Ajay, Eguchi, Yuichiro, El Kassas, Mohamed, Castellanos-Fernandez, Marlen, George, Jacob, Jacobson, Ira M., Bugianesi, Elisabetta, Wong, Vincent Wai-Sun, Arrese, Marco, de Ledinghen, Victor, Romero-Gomez, Manuel, Mendez-Sanchez, Nahum, Ahmed, Aijaz, Wong, Robert, Papatheodoridis, Georgios, Serfaty, Lawrence, Younossi, Issah, Nader, Fatema, Ziayee, Mariam, Afendy, Arian

“…Non-alcoholic and alcohol-related fatty liver disease are overlapping diseases in which metabolic syndrome and alcohol consumption each contribute to…”
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THU-437-The Global Epidemiology on non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in patients with type 2 diabetes mellitus: A systematic review and meta-analysis by Younossi, Zobair, Golabi, Pegah, Deavila, Leyla, Paik, James, Srishord, Manirath, Fukui, Natsu, Qiu, Ying, Burns, Leah, Afendy, Arian, Nader, Fatema

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Validation of endogenous reference genes for qRT-PCR analysis of human visceral adipose samples by Mehta, Rohini, Birerdinc, Aybike, Hossain, Noreen, Afendy, Arian, Chandhoke, Vikas, Younossi, Zobair, Baranova, Ancha

“…Given the epidemic proportions of obesity worldwide and the concurrent prevalence of metabolic syndrome, there is an urgent need for better understanding the…”
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Performance of the Enhanced Liver Fibrosis Test to Estimate Advanced Fibrosis Among Patients With Nonalcoholic Fatty Liver Disease by Younossi, Zobair M, Felix, Sean, Jeffers, Thomas, Younossi, Elena, Nader, Fatema, Pham, Huong, Afendy, Arian, Cable, Rebecca, Racila, Andrei, Younoszai, Zahra, Lam, Brian P, Golabi, Pegah, Henry, Linda, Stepanova, Maria

“…The most important surrogate for increased risk of adverse clinical outcomes among patients with nonalcoholic fatty liver disease (NAFLD) is the patient's…”
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Long-term Benefits of Sustained Virologic Response for Patient-Reported Outcomes in Patients With Chronic Hepatitis C Virus Infection by Younossi, Zobair M., Stepanova, Maria, Racila, Andrei, Afendy, Arian, Lawitz, Eric J., Schwabe, Christian, Ruane, Peter J., Lalezari, Jay, Reddy, K. Rajender, Jacobson, Ira M., Muir, Andrew J., Gaggar, Anuj, Myers, Robert P., Younossi, Issah, Nader, Fatema

“…Patients with hepatitis C virus (HCV) infections who achieve a sustained virologic response (SVR) to treatment have improved patient-reported outcomes (PROs)…”
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1448-P: Enhanced Liver Fibrosis (ELF) Test Can Accurately Predict Advanced Fibrosis in Patients with Type 2 Diabetes and Nonalcoholic Fatty Liver Disease (NAFLD) by YOUNOSSI, ZOBAIR, FELIX, SEAN, JEFFERS, THOMAS, YOUNOSSI, ELENA, NADER, FATEMA, PHAM, HUONG, AFENDY, ARIAN, CABLE, REBECCA, RACILA, ANDREI, YOUNOSZAI, ZAHRA, LAM, BRIAN P., GOLABI, PEGAH, HENRY, LINDA, CLEMENT, STEPHEN, STEPANOVA, MARIA

“…Background: The ELF test (score calculated from markers of fibrosis: hyaluronic acid, procollagen III amino-terminal peptide, and tissue inhibitor of matrix…”
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SAT-269-The sustained deleterious impact of viremia on patient reported outcomes in patients with chronic hepatitis C who don’t achieve sustained virologic response by Younossi, Zobair, Stepanova, Maria, Racilla, Andrei, Afendy, Arian, Jacobson, Ira, Muir, Andrew, Pol, Stanislas, Zeuzem, Stefan, Lawitz, Eric, Gaggar, Anuj, Myers, Robert, Younossi, Issah, Nader, Fatema

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Non-alcoholic steatohepatitis (NASH) in patients with polycystic ovarian syndrome (PCOS) by Hossain, Noreen, Stepanova, Maria, Afendy, Arian, Nader, Fatema, Younossi, Youssef, Rafiq, Nila, Goodman, Zachary, Younossi, Zobair M.

“…Abstract Background. Both non-alcoholic steatohepatitis (NASH) and polycystic ovary syndrome (PCOS) are associated with metabolic syndrome (MS) and insulin…”
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954 – Chronic Hepatitis C (CHC) Patients Who Do Not Achieve Sustained Virologic Response (SVR) Experience Worsening of Their Health-Related Quality of Life (HRQL) by Younossi, Zobair M., Stepanova, Maria, Racila, Andrei, Afendy, Arian, Jacobson, Ira M., Muir, Andrew J., Pol, Stanislas, Zeuzem, Stefan, Lawitz, Eric, Gaggar, Anuj, Myers, Robert P., Younossi, Issah M., Nader, Fatema

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Molecular signature of adipose tissue in patients with both non-alcoholic fatty liver disease (NAFLD) and polycystic ovarian syndrome (PCOS) by Baranova, Ancha, Tran, Thuy Phuong, Afendy, Arian, Wang, Lei, Shamsaddini, Amirhossein, Mehta, Rohini, Chandhoke, Vikas, Birerdinc, Aybike, Younossi, Zobair M

“…Polycystic ovarian syndrome (PCOS) is one of the most common reproductive disorders with strong association with both insulin resistance and non-alcoholic…”
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Expression of genes for microRNA-processing enzymes is altered in advanced non-alcoholic fatty liver disease by Sharma, Haveesh, Estep, Michael, Birerdinc, Aybike, Afendy, Arian, Moazzez, Amir, Elariny, Hazem, Goodman, Zachary, Chandhoke, Vikas, Baranova, Ancha, Younossi, Zobair M

“…Background and Aim Recently, microRNAs (miRNA) have been linked to the pathogenesis of non‐alcoholic fatty liver disease (NAFLD) and its progression to…”
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Hepatic Gene Expression of Caucasian and African-American Patients with Obesity-Related Non-Alcoholic Fatty Liver Disease by Stepanova, Maria, Hossain, Noreen, Afendy, Arian, Perry, Kellie, Goodman, Zachary D., Baranova, Ancha, Younossi, Zobair

“…Background/aim There is increasing data suggesting that African Americans with NAFLD tend to have less progressive liver disease. The aim of this study is to…”
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