Search Results - "AERTSEN, Abram"

The impact of insertion sequences on bacterial genome plasticity and adaptability by Vandecraen, Joachim, Chandler, Michael, Aertsen, Abram, Van Houdt, Rob

“…Transposable elements (TE), small mobile genetic elements unable to exist independently of the host genome, were initially believed to be exclusively…”
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Protein aggregates encode epigenetic memory of stressful encounters in individual Escherichia coli cells by Govers, Sander K, Mortier, Julien, Adam, Antoine, Aertsen, Abram

“…Protein misfolding and aggregation are typically perceived as inevitable and detrimental processes tied to a stress- or age-associated decline in cellular…”
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The role of variable DNA tandem repeats in bacterial adaptation by Zhou, Kai, Aertsen, Abram, Michiels, Chris W.

“…Abstract DNA tandem repeats (TRs), also designated as satellite DNA, are inter- or intragenic nucleotide sequences that are repeated two or more times in a…”
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Engineered endolysin-based "artilysins" to combat multidrug-resistant gram-negative pathogens by Briers, Yves, Walmagh, Maarten, Van Puyenbroeck, Victor, Cornelissen, Anneleen, Cenens, William, Aertsen, Abram, Oliveira, Hugo, Azeredo, Joana, Verween, Gunther, Pirnay, Jean-Paul, Miller, Stefan, Volckaert, Guido, Lavigne, Rob

“…The global threat to public health posed by emerging multidrug-resistant bacteria in the past few years necessitates the development of novel approaches to…”
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Art-175 Is a Highly Efficient Antibacterial against Multidrug-Resistant Strains and Persisters of Pseudomonas aeruginosa by BRIERS, Yves, WALMAGH, Maarten, LAVIGNE, Rob, GRYMONPREZ, Barbara, BIEBL, Manfred, PIRNAY, Jean-Paul, DEFRAINE, Valerie, MICHIELS, Jan, CENENS, William, AERTSEN, Abram, MILLER, Stefan

“…Artilysins constitute a novel class of efficient enzyme-based antibacterials. Specifically, they covalently combine a bacteriophage-encoded endolysin, which…”
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Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii by Defraine, Valerie, Schuermans, Joris, Grymonprez, Barbara, Govers, Sander K, Aertsen, Abram, Fauvart, Maarten, Michiels, Jan, Lavigne, Rob, Briers, Yves

“…Bacteriophage-encoded endolysins have shown promise as a novel class of antibacterials with a unique mode of action, i.e., peptidoglycan degradation. However,…”
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The expression of virulence genes increases membrane permeability and sensitivity to envelope stress in Salmonella Typhimurium by Sobota, Malgorzata, Rodilla Ramirez, Pilar Natalia, Cambré, Alexander, Rocker, Andrea, Mortier, Julien, Gervais, Théo, Haas, Tiphaine, Cornillet, Delphine, Chauvin, Dany, Hug, Isabelle, Julou, Thomas, Aertsen, Abram, Diard, Médéric

“…Virulence gene expression can represent a substantial fitness cost to pathogenic bacteria. In the model entero-pathogen Salmonella Typhimurium (S.Tm), such…”
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Impact of high hydrostatic pressure on bacterial proteostasis by Gayán, Elisa, Govers, Sander K., Aertsen, Abram

“…High hydrostatic pressure (HHP) is an important factor that limits microbial growth in deep-sea ecosystems to specifically adapted piezophiles. Furthermore,…”
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Regulation and quality control by Lon-dependent proteolysis by Van Melderen, Laurence, Aertsen, Abram

“…After their first discovery in Escherichia coli, Lon homologues were found to be widely distributed among prokaryotes to eukaryotes. The ATP-dependent Lon…”
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Aggregating sequences that occur in many proteins constitute weak spots of bacterial proteostasis by Khodaparast, Ladan, Khodaparast, Laleh, Gallardo, Rodrigo, Louros, Nikolaos N., Michiels, Emiel, Ramakrishnan, Reshmi, Ramakers, Meine, Claes, Filip, Young, Lydia, Shahrooei, Mohammad, Wilkinson, Hannah, Desager, Matyas, Mengistu Tadesse, Wubishet, Nilsson, K. Peter R., Hammarström, Per, Aertsen, Abram, Carpentier, Sebastien, Van Eldere, Johan, Rousseau, Frederic, Schymkowitz, Joost

“…Aggregation is a sequence-specific process, nucleated by short aggregation-prone regions (APRs) that can be exploited to induce aggregation of proteins…”
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Viral Transmission Dynamics at Single-Cell Resolution Reveal Transiently Immune Subpopulations Caused by a Carrier State Association by Cenens, William, Makumi, Angela, Govers, Sander K, Lavigne, Rob, Aertsen, Abram

“…Monitoring the complex transmission dynamics of a bacterial virus (temperate phage P22) throughout a population of its host (Salmonella Typhimurium) at single…”
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Bacteriophage‐mediated interference of the c‐di‐GMP signalling pathway in Pseudomonas aeruginosa by De Smet, Jeroen, Wagemans, Jeroen, Hendrix, Hanne, Staes, Ines, Visnapuu, Annegrete, Horemans, Benjamin, Aertsen, Abram, Lavigne, Rob

“…C‐di‐GMP is a key signaling molecule which impacts bacterial motility and biofilm formation and is formed by the condensation of two GTP molecules by a…”
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Evolutionary trade-off between heat shock resistance, growth at high temperature, and virulence expression in Salmonella Typhimurium by Berdejo, Daniel, Mortier, Julien, Cambré, Alexander, Sobota, Malgorzata, Van Eyken, Ronald, Kim, Tom Dongmin, Vanoirbeek, Kristof, García Gonzalo, Diego, Pagán, Rafael, Diard, Médéric, Aertsen, Abram

“…Understanding the evolutionary dynamics of foodborne pathogens throughout our food production chain is of utmost importance. In this study, we reveal that…”
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Rapid phenotypic individualization of bacterial sister cells by Govers, Sander K., Adam, Antoine, Blockeel, Hendrik, Aertsen, Abram

“…A growing bacterium typically divides into two genetically identical and morphologically similar sister cells and eventually gives rise to a clonal population…”
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Emergence and Stability of High-Pressure Resistance in Different Food-Borne Pathogens by VANLINT, Dietrich, RUTTEN, Nele, MICHIELS, Chris W, AERTSEN, Abram

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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RpoS-independent evolution reveals the importance of attenuated cAMP/CRP regulation in high hydrostatic pressure resistance acquisition in E. coli by Gayán, Elisa, Cambré, Alexander, Michiels, Chris W., Aertsen, Abram

“…High hydrostatic pressure (HHP) processing is an attractive non-thermal alternative to food pasteurization. Nevertheless, the large inter- and intra-species…”
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Biotechnology under high pressure: applications and implications by Aertsen, Abram, Meersman, Filip, Hendrickx, Marc E.G, Vogel, Rudi F, Michiels, Chris W

“…Pressure is a thermodynamic parameter whose unique effects on biological systems are increasingly being studied in a growing number of scientific fields. As…”
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Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome by Van den Bossche, An, Hardwick, Steven W, Ceyssens, Pieter-Jan, Hendrix, Hanne, Voet, Marleen, Dendooven, Tom, Bandyra, Katarzyna J, De Maeyer, Marc, Aertsen, Abram, Noben, Jean-Paul, Luisi, Ben F, Lavigne, Rob

“…In all domains of life, the catalysed degradation of RNA facilitates rapid adaptation to changing environmental conditions, while destruction of foreign RNA is…”
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Digital Microfluidics for Single Bacteria Capture and Selective Retrieval Using Optical Tweezers by Tewari Kumar, Phalguni, Decrop, Deborah, Safdar, Saba, Passaris, Ioannis, Kokalj, Tadej, Puers, Robert, Aertsen, Abram, Spasic, Dragana, Lammertyn, Jeroen

“…When screening microbial populations or consortia for interesting cells, their selective retrieval for further study can be of great interest. To this end,…”
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A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics by Masschelein, Joleen, Mattheus, Wesley, Gao, Ling-Jie, Moons, Pieter, Van Houdt, Rob, Uytterhoeven, Birgit, Lamberigts, Chris, Lescrinier, Eveline, Rozenski, Jef, Herdewijn, Piet, Aertsen, Abram, Michiels, Chris, Lavigne, Rob

“…Serratia plymuthica strain RVH1, initially isolated from an industrial food processing environment, displays potent antimicrobial activity towards a broad…”
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