Search Results - "AERTS, Isabelle"

A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression by Liu, Jing, Ottaviani, Daniela, Sefta, Meriem, Desbrousses, Céline, Chapeaublanc, Elodie, Aschero, Rosario, Sirab, Nanor, Lubieniecki, Fabiana, Lamas, Gabriela, Tonon, Laurie, Dehainault, Catherine, Hua, Clément, Fréneaux, Paul, Reichman, Sacha, Karboul, Narjesse, Biton, Anne, Mirabal-Ortega, Liliana, Larcher, Magalie, Brulard, Céline, Arrufat, Sandrine, Nicolas, André, Elarouci, Nabila, Popova, Tatiana, Némati, Fariba, Decaudin, Didier, Gentien, David, Baulande, Sylvain, Mariani, Odette, Dufour, Florent, Guibert, Sylvain, Vallot, Céline, Rouic, Livia Lumbroso-Le, Matet, Alexandre, Desjardins, Laurence, Pascual-Pasto, Guillem, Suñol, Mariona, Catala-Mora, Jaume, Llano, Genoveva Correa, Couturier, Jérôme, Barillot, Emmanuel, Schaiquevich, Paula, Gauthier-Villars, Marion, Stoppa-Lyonnet, Dominique, Golmard, Lisa, Houdayer, Claude, Brisse, Hervé, Bernard-Pierrot, Isabelle, Letouzé, Eric, Viari, Alain, Saule, Simon, Sastre-Garau, Xavier, Doz, François, Carcaboso, Angel M., Cassoux, Nathalie, Pouponnot, Celio, Goureau, Olivier, Chantada, Guillermo, de Reyniès, Aurélien, Aerts, Isabelle, Radvanyi, François

“…Retinoblastoma is the most frequent intraocular malignancy in children, originating from a maturing cone precursor in the developing retina. Little is known on…”
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Preliminary Efficacy of the Anti-Insulin–Like Growth Factor Type 1 Receptor Antibody Figitumumab in Patients With Refractory Ewing Sarcoma by JUERGENS, Heribert, DAW, Najat C, TAO WANG, GREEN, Stephanie, PACCAGNELLA, Luisa, GUALBERTO, Antonio, GEOERGER, Birgit, FERRARI, Stefano, VILLARROEL, Milena, AERTS, Isabelle, WHELAN, Jeremy, DIRKSEN, Uta, HIXON, Mary L, DONGHUA YIN

“…Patients with Ewing sarcoma (ES) with metastases and those who relapse fare poorly and receive therapies that carry significant toxicity. This phase 1/2 study…”
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Single-cell multiomics reveals the interplay of clonal evolution and cellular plasticity in hepatoblastoma by Roehrig, Amélie, Hirsch, Theo Z., Pire, Aurore, Morcrette, Guillaume, Gupta, Barkha, Marcaillou, Charles, Imbeaud, Sandrine, Chardot, Christophe, Gonzales, Emmanuel, Jacquemin, Emmanuel, Sekiguchi, Masahiro, Takita, Junko, Nagae, Genta, Hiyama, Eiso, Guérin, Florent, Fabre, Monique, Aerts, Isabelle, Taque, Sophie, Laithier, Véronique, Branchereau, Sophie, Guettier, Catherine, Brugières, Laurence, Fresneau, Brice, Zucman-Rossi, Jessica, Letouzé, Eric

“…Hepatoblastomas (HB) display heterogeneous cellular phenotypes that influence the clinical outcome, but the underlying mechanisms are poorly understood. Here,…”
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Preneoplastic liver colonization by 11p15.5 altered mosaic cells in young children with hepatoblastoma by Pilet, Jill, Hirsch, Theo Z., Gupta, Barkha, Roehrig, Amélie, Morcrette, Guillaume, Pire, Aurore, Letouzé, Eric, Fresneau, Brice, Taque, Sophie, Brugières, Laurence, Branchereau, Sophie, Chardot, Christophe, Aerts, Isabelle, Sarnacki, Sabine, Fabre, Monique, Guettier, Catherine, Rebouissou, Sandra, Zucman-Rossi, Jessica

“…Pediatric liver tumors are very rare tumors with the most common diagnosis being hepatoblastoma. While hepatoblastomas are predominantly sporadic, around 15%…”
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Adjuvant therapy of histopathological risk factors of retinoblastoma in Europe: A survey by the European Retinoblastoma Group (EURbG) by Dittner‐Moormann, Sabine, Reschke, Madlen, Abbink, Floor C. H., Aerts, Isabelle, Atalay, Hatice Tuba, Fedorovna Bobrova, Nadezhda, Biewald, Eva, Brecht, Ines B., Caspi, Shani, Cassoux, Nathalie, Castela, Guilherme, Diarra, Yelena, Duncan, Catriona, Ebinger, Martin, Garcia Aldana, David, Hadjistilianou, Doris, Kepák, Tomáš, Klett, Artur, Kiratli, Hayyam, Maka, Erika, Opocher, Enrico, Pawinska‐Wasikowska, Katarzyna, Rascon, Jelena, Russo, Ida, Rutynowska‐Pronicka, Olga, Sábado Álvarez, Constantino, Pacheco, Sonsoles San Roman, Svojgr, Karel, Timmermann, Beate, Vishnevskia‐Dai, Vicktoria, Eggert, Angelika, Ritter‐Sovinz, Petra, Bechrakis, Nikolaos E., Jenkinson, Helen, Moll, Annette, Munier, Francis L., Popovic, Maja Beck, Chantada, Guillermo, Doz, François, Ketteler, Petra

“…Introduction Advanced intraocular retinoblastoma can be cured by enucleation, but spread of retinoblastoma cells beyond the natural limits of the eye is…”
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A Parent-of-Origin Effect Impacts the Phenotype in Low Penetrance Retinoblastoma Families Segregating the c.1981C>T/p.Arg661Trp Mutation of RB1 by Eloy, Philippine, Dehainault, Catherine, Sefta, Meriem, Aerts, Isabelle, Doz, François, Cassoux, Nathalie, Lumbroso le Rouic, Livia, Stoppa-Lyonnet, Dominique, Radvanyi, François, Millot, Gaël A, Gauthier-Villars, Marion, Houdayer, Claude

“…Retinoblastoma (Rb), the most common pediatric intraocular neoplasm, results from inactivation of both alleles of the RB1 tumor suppressor gene. The second…”
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Results of a Multicenter Prospective Study on the Postoperative Treatment of Unilateral Retinoblastoma After Primary Enucleation by Aerts, Isabelle, Sastre-Garau, Xavier, Savignoni, Alexia, Lumbroso-Le Rouic, Livia, Thebaud-Leculée, Estelle, Frappaz, Didier, Coze, Carole, Thomas, Caroline, Gauthier-Villars, Marion, Lévy-Gabriel, Christine, Brisse, Hervé J, Desjardins, Laurence, Doz, François

“…The objective of this prospective study was to assess overall survival and event-free survival in patients with intraocular unilateral retinoblastoma…”
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Retinoblastoma by Aerts, Isabelle, Lumbroso-Le Rouic, Livia, Gauthier-Villars, Marion, Brisse, Hervé, Doz, François, Desjardins, Laurence

“…Retinoblastoma is a rare eye tumor of childhood that arises in the retina. It is the most common intraocular malignancy of infancy and childhood; with an…”
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Pure and mixed fibrolamellar hepatocellular carcinomas differ in natural history and prognosis after complete surgical resection by Malouf, Gabriel G., Brugières, Laurence, Le Deley, Marie‐Cécile, Faivre, Sandrine, Fabre, Monique, Paradis, Valérie, Aerts, Isabelle, Le Tourneau, Christophe, Dreyer, Chantal, Branchereau, Sophie, Belghiti, Jacques, Raymond, Eric

“…BACKGROUND: The purpose of the current study was to describe pure and mixed fibrolamellar hepatocellular carcinoma (FL‐HCC). METHODS: Consecutive patients with…”
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Analysis of ototoxicity in young children receiving carboplatin in the context of conservative management of unilateral or bilateral retinoblastoma by Jehanne, Mathilde, Lumbroso-Le Rouic, Livia, Savignoni, Alexia, Aerts, Isabelle, Mercier, Ghislaine, Bours, Danielle, Desjardins, Laurence, Doz, François

“…Background Carboplatin plays an important role in the conservative management of retinoblastoma, but is associated with risk of ototoxicity in these young…”
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Metronomic Four-Drug Regimen Has Anti-tumor Activity in Pediatric Low-Grade Glioma; The Results of a Phase II Clinical Trial by Verschuur, Arnauld, Heng-Maillard, Marie-Amélie, Dory-Lautrec, Philippe, Truillet, Romain, Jouve, Elisabeth, Chastagner, Pascal, Leblond, Pierre, Aerts, Isabelle, Honoré, Stéphane, Entz-Werle, Natasha, Sirvent, Nicolas, Gentet, Jean-Claude, Corradini, Nadège, André, Nicolas

“…Metronomic chemotherapy (MC) is defined as the frequent administration of chemotherapy at doses below the maximal tolerated dose and with no prolonged…”
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A phase 1, first-in-child, multicenter study to evaluate the safety and efficacy of the oncolytic herpes virus talimogene laherparepvec in pediatric patients with advanced solid tumors by Moreno, Lucas, Teira, Pierre, Croop, James M, Gerber, Nicolas U, André, Nicolas, Aerts, Isabelle, Gros Subias, Luis, De Wilde, Bram, Bautista, Francisco, Turpin, Brian, Kunduri, Srinivasa, Hamidi, Ali, Lawrence, Tatiana, Streby, Keri A

“…The survival rates for pediatric patients with relapsed and refractory tumors are poor. Successful treatment strategies are currently lacking and there remains…”
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Trilateral retinoblastoma: neuroimaging characteristics and value of routine brain screening on admission by Rodjan, Firazia, de Graaf, Pim, Brisse, Hervé J., Göricke, Sophia, Maeder, Philippe, Galluzzi, Paolo, Aerts, Isabelle, Alapetite, Claire, Desjardins, Laurence, Wieland, Regina, Popovic, Maja Beck, Diezi, Manuel, Munier, Francis L., Hadjistilianou, Theodora, Knol, Dirk L., Moll, Annette C., Castelijns, Jonas A.

“…Trilateral retinoblastoma (TRb) is a rare disease associating intraocular retinoblastoma with intracranial primitive neuroectodermal tumor. Treatment is…”
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Osteosarcoma without prior retinoblastoma related to RB1 low‐penetrance germline pathogenic variants: A novel type of RB1‐related hereditary predisposition syndrome? by Imbert‐Bouteille, Marion, Gauthier‐Villars, Marion, Leroux, Dominique, Meunier, Isabelle, Aerts, Isabelle, Lumbroso‐Le Rouic, Livia, Lejeune, Sophie, Delnatte, Capucine, Abadie, Caroline, Pujol, Pascal, Houdayer, Claude, Corsini, Carole

“…Background Retinoblastoma (Rb) is a rare intraocular malignant tumor in children with high overall survival. Predisposition to Rb is linked to RB1 germline…”
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Capacitive response of PDMS-coated IDE platforms directly exposed to aqueous solutions containing volatile organic compounds by Staginus, Judith, Aerts, Isabelle M, Chang, Zu-yao, Meijer, Gerard C.M, de Smet, Louis C.P.M, Sudhölter, Ernst J.R

“…In this work we report on the capacitive response of interdigitated electrodes (IDEs) covered with a thin (~50μm) polydimethyl siloxane (PDMS; Sylgard®184)…”
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Conservative Treatments of Intraocular Retinoblastoma by Rouic, Livia Lumbroso-Le, MD, Aerts, Isabelle, MD, Lévy-Gabriel, Christine, MD, Dendale, Rémi, MD, Sastre, Xavier, MD, Esteve, Marc, MD, Asselain, Bernard, MD, Bours, Danielle, MD, Doz, François, MD, Desjardins, Laurence, MD

“…Objective To describe the efficacy of conservative management of retinoblastoma by an association of conservative ocular therapies and chemothermotherapy…”
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In vivo efficacy of photodynamic therapy in three new xenograft models of human retinoblastoma by Aerts, Isabelle, MD, Leuraud, Pascal, Blais, Jocelyne, Pouliquen, Anne-lise, Maillard, Philippe, Houdayer, Claude, Couturier, Jérôme, Sastre-Garau, Xavier, Grierson, David, Doz, François, Poupon, Marie France

“…Summary Purpose Retinoblastoma is the most common primary intraocular tumor in children. In industrialized countries, 95% of patients are cured by chemotherapy…”
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Outcome of second malignancies after retinoblastoma: a retrospective analysis of 25 patients treated at the Institut Curie by Aerts, Isabelle, Pacquement, Hélène, Doz, François, Mosseri, Véronique, Desjardins, Laurence, Sastre, Xavier, Michon, Jean, Rodriguez, José, Schlienger, Pierre, Zucker, Jean-Michel, Quintana, Erica

“…Retinoblastoma is usually curable in developed countries. The morbidity and mortality of patients with hereditary retinoblastoma is still threatened by the…”
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Combined in situ hypothermic liver preservation and cardioplegia for resection of hepatoblastoma with intra-atrial extension in a 3 year old child by Thalhammer, Julian, Fanna, Martina, Gaudin, Régis, Martinon-Siringo, Claire, Berteloot, Laureline, Galmiche-Rolland, Louise, Aerts, Isabelle, Orbach, Daniel, Capito, Carmen, Chardot, Christophe

“…Abstract Cure of hepatoblastoma requires complete macro- and microscopic resection of the tumor, without tumor rupture. In case of hepatoblastoma with…”
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Efficacy and Safety of Trametinib Monotherapy or in Combination With Dabrafenib in Pediatric BRAF V600-Mutant Low-Grade Glioma by Bouffet, Eric, Geoerger, Birgit, Moertel, Christopher, Whitlock, James A, Aerts, Isabelle, Hargrave, Darren, Osterloh, Lisa, Tan, Eugene, Choi, Jeea, Russo, Mark, Fox, Elizabeth

“…V600 mutations occur in many childhood cancers, including approximately 20% of low-grade gliomas (LGGs). Here, we describe a phase I/II study establishing…”
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