Search Results - "ADRIAN, L"
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The Problem of Curcumin and Its Bioavailability: Could Its Gastrointestinal Influence Contribute to Its Overall Health-Enhancing Effects?
Published in Advances in nutrition (Bethesda, Md.) (01-01-2018)“…Curcumin, from the spice turmeric, exhibits anti-inflammatory, antioxidant, anticancer, antiviral, and neurotrophic activity and therefore holds promise as a…”
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2
Advances in Hypoxia-Inducible Factor Biology
Published in Cell metabolism (06-02-2018)“…Hypoxia-inducible factor (HIF), a central regulator for detecting and adapting to cellular oxygen levels, transcriptionally activates genes modulating oxygen…”
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3
How cancer metabolism is tuned for proliferation and vulnerable to disruption
Published in Nature (London) (15-11-2012)“…Cancer metabolism has received a substantial amount of interest over the past decade. The advances in analytical tools have, along with the rapid progress of…”
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4
Antiangiogenic therapy in oncology: current status and future directions
Published in The Lancet (British edition) (30-07-2016)“…Summary Angiogenesis, the formation of new blood vessels from pre-existing vessels, has been validated as a target in several tumour types through randomised…”
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5
Cognitive behaviour therapy and inflammation: A systematic review of its relationship and the potential implications for the treatment of depression
Published in Australian & New Zealand Journal of Psychiatry (01-06-2017)“…Objective: There is growing evidence confirming increased inflammation in a subset of adults with depression. The impact of this relationship has mostly been…”
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6
Endoscope or microscope‐guided pediatric tympanoplasty? Comparison of grafting technique and outcome
Published in The Laryngoscope (01-11-2017)“…Objectives/Hypothesis To review experience from the introduction of totally endoscopic ear surgery (TEES) to a pediatric tympanoplasty practice to identify…”
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7
Salvia (Sage): A Review of its Potential Cognitive-Enhancing and Protective Effects
Published in Drugs in R & D (Online) (01-03-2017)“…Genus Salvia , commonly known as sage, is the largest genus in the Lamiaceae family. It comprises many species traditionally used as brain-enhancing tonics. In…”
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Journal Article Book Review -
8
Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot
Published in Cell metabolism (12-04-2016)“…Cell metabolism and growth are matched to nutrient availability via the amino-acid-regulated mechanistic target of rapamycin complex 1 (mTORC1). Transporters…”
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Potential Role of Curcumin for the Treatment of Major Depressive Disorder
Published in CNS drugs (01-02-2022)“…Curcumin is the major biologically active polyphenolic constituent in the turmeric plant ( Curcuma longa ) that has been shown to have antioxidant,…”
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Glycogen metabolism has a key role in the cancer microenvironment and provides new targets for cancer therapy
Published in Journal of molecular medicine (Berlin, Germany) (01-02-2016)“…Metabolic reprogramming is a hallmark of cancer cells and contributes to their adaption within the tumour microenvironment and resistance to anticancer…”
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11
Development of cancer metabolism as a therapeutic target: new pathways, patient studies, stratification and combination therapy
Published in British journal of cancer (01-01-2020)“…Cancer metabolism has undergone a resurgence in the last decade, 70 years after Warburg described aerobic glycolysis as a feature of cancer cells. A wide range…”
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12
COVID-19 and cancer research
Published in British journal of cancer (01-09-2020)“…Summary The COVID-19 pandemic has had a devastating effect on human lives and society. The accompanying editorial summarises some of the major effects on…”
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13
The biodiversity and ecosystem service contributions and trade-offs of forest restoration approaches
Published in Science (American Association for the Advancement of Science) (20-05-2022)“…Forest restoration is being scaled up globally to deliver critical ecosystem services and biodiversity benefits; however, there is a lack of rigorous…”
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14
Biomarkers to predict the clinical efficacy of bevacizumab in cancer
Published in The lancet oncology (01-12-2010)“…Summary Bevacizumab is a monoclonal antibody against vascular endothelial growth factor that has antiangiogenic activity and improves progression-free survival…”
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15
75th anniversary of the British Journal of Cancer
Published in British journal of cancer (02-02-2023)Get full text
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16
Host Selection of Microbiota via Differential Adhesion
Published in Cell host & microbe (13-04-2016)“…The host epithelium is the critical interface with microbial communities, but the mechanisms by which the host regulates these communities are poorly…”
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Foundations for the design and implementation of synthetic genetic circuits
Published in Nature reviews. Genetics (01-06-2012)“…Key Points Synthetic gene circuits are designed to implement novel biologic function, including cellular logic, dynamics and complex cellular and multicellular…”
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18
Algebraic Diagrammatic Construction Schemes Employing the Intermediate State Formalism: Theory, Capabilities, and Interpretation
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (17-08-2023)“…Algebraic diagrammatic construction (ADC) schemes represent a family of ab initio methods for the calculation of excited electronic states and…”
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Is it still worth pursuing the repurposing of metformin as a cancer therapeutic?
Published in British journal of cancer (06-04-2023)“…Over the past 15 years, there has been great interest in the potential to repurpose the diabetes drug, metformin, as a cancer treatment. However, despite…”
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Metabolic and hypoxic adaptation to anti‐angiogenic therapy: a target for induced essentiality
Published in EMBO molecular medicine (01-04-2015)“…Anti‐angiogenic therapy has increased the progression‐free survival of many cancer patients but has had little effect on overall survival, even in colon cancer…”
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