Search Results - "ADRIAENSSENS, E"

Identification and Characterization of GLP-1 Receptor-Expressing Cells Using a New Transgenic Mouse Model by RICHARDS, Paul, PARKER, Helen E, ADRIAENSSENS, Alice E, HODGSON, Joshua M, CORK, Simon C, TRAPP, Stefan, GRIBBLE, Fiona M, REIMANN, Frank

“…GLP-1 is an intestinal hormone with widespread actions on metabolism. Therapies based on GLP-1 are highly effective because they increase glucose-dependent…”
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Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets by Adriaenssens, Alice E., Svendsen, Berit, Lam, Brian Y. H., Yeo, Giles S. H., Holst, Jens J., Reimann, Frank, Gribble, Fiona M.

“…Aims/hypothesis Intra-islet and gut–islet crosstalk are critical in orchestrating basal and postprandial metabolism. The aim of this study was to identify…”
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Reversible changes in pancreatic islet structure and function produced by elevated blood glucose by Brereton, Melissa F., Iberl, Michaela, Shimomura, Kenju, Zhang, Quan, Adriaenssens, Alice E., Proks, Peter, Spiliotis, Ioannis I., Dace, William, Mattis, Katia K., Ramracheya, Reshma, Gribble, Fiona M., Reimann, Frank, Clark, Anne, Rorsman, Patrik, Ashcroft, Frances M.

“…Diabetes is characterized by hyperglycaemia due to impaired insulin secretion and aberrant glucagon secretion resulting from changes in pancreatic islet cell…”
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GIPR Function in the Central Nervous System: Implications and Novel Perspectives for GIP-Based Therapies in Treating Metabolic Disorders by Samms, Ricardo J, Sloop, Kyle W, Gribble, Fiona M, Reimann, Frank, Adriaenssens, Alice E

“…During the past decade, pharmaceutical engineering of unimolecular agents has revealed the therapeutic potential of glucose-dependent insulinotropic…”
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The core clock gene, Bmal1, and its downstream target, the SNARE regulatory protein secretagogin, are necessary for circadian secretion of glucagon-like peptide-1 by Biancolin, Andrew D., Martchenko, Alexandre, Mitova, Emilia, Gurges, Patrick, Michalchyshyn, Everan, Chalmers, Jennifer A., Doria, Alessandro, Mychaleckyj, Josyf C., Adriaenssens, Alice E., Reimann, Frank, Gribble, Fiona M., Gil-Lozano, Manuel, Cox, Brian J., Brubaker, Patricia L.

“…The incretin hormone glucagon-like peptide-1 (GLP-1) is secreted from intestinal L-cells upon nutrient intake. While recent evidence has shown that GLP-1 is…”
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Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice by Lewis, Jo E., Woodward, Orla RM, Nuzzaci, Danaé, Smith, Christopher A., Adriaenssens, Alice E., Billing, Lawrence, Brighton, Cheryl, Phillips, Benjamin U., Tadross, John A., Kinston, Sarah J., Ciabatti, Ernesto, Göttgens, Berthold, Tripodi, Marco, Hornigold, David, Baker, David, Gribble, Fiona M., Reimann, Frank

“…Insulin-like peptide 5 (INSL5) signalling, through its cognate receptor relaxin/insulin-like family peptide receptor 4 (RXFP4), has been reported to be…”
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Complete Genome Sequence of the Novel Escherichia coli Phage phAPEC8 by TSONOS, J, ADRIAENSSENS, E. M, KLUMPP, J, HERNALSTEENS, J.-P, LAVIGNE, R, DE GREVE, H

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Complete Genome Sequence of the Giant Pseudomonas Phage Lu11 by Adriaenssens, E M, Mattheus, W, Cornelissen, A, Shaburova, O, Krylov, V N, Kropinski, A M, Lavigne, R

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Inhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion by Stamenkovic, Jelena A, Andersson, Lotta E, Adriaenssens, Alice E, Bagge, Annika, Sharoyko, Vladimir V, Gribble, Fiona, Reimann, Frank, Wollheim, Claes B, Mulder, Hindrik, Spégel, Peter

“…Altered secretion of insulin as well as glucagon has been implicated in the pathogenesis of Type 2 diabetes (T2D), but the mechanisms controlling glucagon…”
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ST6GalNAc I expression in MDA-MB-231 breast cancer cells greatly modifies their O-glycosylation pattern and enhances their tumourigenicity by Julien, S, Adriaenssens, E, Ottenberg, K, Furlan, A, Courtand, G, Vercoutter-Edouart, A.-S, Hanisch, F.-G, Delannoy, P, Le Bourhis, X

“…Sialyl-Tn is a carbohydrate antigen overexpressed in several epithelial cancers, including breast cancer, and usually associated with poor prognosis. Sialyl-Tn…”
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Interlaboratory comparison exercise for the determination of As, Cd, Ni and Pb in PM10 in Europe by GERBOLES, M, BUZICA, D, SEGA, K, JURASOVIC, J, RYCHLIK, S, RABINAK, E, TANET, G, PASSARELLA, R, PEDRONI, V, KARLSSON, V, ALLEMAN, L, PFEFFER, U, BROWN, RJ. C, GLADTKE, D, OLSCHEWSKI, A, O'LEARY, B, O'DWYER, M, POCKEVICIUTE, D, BIEL-CWIKOWSKA, J, TURSIC, J, YARDLEY, R. E, HANUS-ILLNAR, A, SALFINGER, M, VALLANT, B, ADRIAENSSENS, E, CLAEYS, N, ROEKENS, E

“…This paper presents the results of an intercomparison exercise for the determination of arsenic (As), cadmium (Cd), nickel (Ni) and lead (Pb) in PM10, which…”
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TrkA overexpression enhances growth and metastasis of breast cancer cells by Lagadec, C, Meignan, S, Adriaenssens, E, Foveau, B, Vanhecke, E, Romon, R, Toillon, R -A, Oxombre, B, Hondermarck, H, Le Bourhis, X

“…The Trk family of neurotrophin tyrosine kinase receptors is emerging as an important player in carcinogenic progression in non-neuronal tissues. Here, we show…”
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Glucose-Dependent Insulinotropic Polypeptide Receptor-Expressing Cells in the Hypothalamus Regulate Food Intake by Adriaenssens, Alice E, Biggs, Emma K, Darwish, Tamana, Tadross, John, Sukthankar, Tanmay, Girish, Milind, Polex-Wolf, Joseph, Lam, Brain Y, Zvetkova, Ilona, Pan, Warren, Chiarugi, Davide, Yeo, Giles S H, Blouet, Clemence, Gribble, Fiona M, Reimann, Frank

“…Ambiguity regarding the role of glucose-dependent insulinotropic polypeptide (GIP) in obesity arises from conflicting reports asserting that both GIP receptor…”
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Nerve Growth Factor Stimulates Proliferation and Survival of Human Breast Cancer Cells through Two Distinct Signaling Pathways by Descamps, Simon, Toillon, Robert-Alain, Adriaenssens, Eric, Pawlowski, Valérie, Cool, Simon M., Nurcombe, Victor, Le Bourhis, Xuefen, Boilly, Bénoni, Peyrat, Jean-Philippe, Hondermarck, Hubert

“…We show here that the neurotrophin nerve growth factor (NGF), which has been shown to be a mitogen for breast cancer cells, also stimulates cell survival…”
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The glucose-dependent insulinotropic polypeptide signaling axis in the central nervous system by Adriaenssens, A.E., Gribble, F.M., Reimann, F.

“…•Glucose-dependent insulinotropic polypeptide receptor (GIPR) is expressed in feeding centres.•GIPR+ cell activation inhibits food intake, yet inhibiting GIPR…”
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GIPR Function in the Central Nervous System: Implications and Novel Perspectives for GIP-Basedz Therapies in Treating Metabolic Disorders by Samms, Ricardo J, Sloop, Kyle W, Gribble, Fiona M, Reimann, Frank, Adriaenssens, Alice E

“…During the past decade, pharmaceutical engineering of unimolecular agents has revealed the therapeutic potential of glucose-dependent insulinotropic…”
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No direct effect of SGLT2 activity on glucagon secretion by Kuhre, Rune E., Ghiasi, Seyed M., Adriaenssens, Alice E., Wewer Albrechtsen, Nicolai J., Andersen, Daniel B., Aivazidis, Alexander, Chen, Lihua, Mandrup-Poulsen, Thomas, Ørskov, Cathrine, Gribble, Fiona M., Reimann, Frank, Wierup, Nils, Tyrberg, Björn, Holst, Jens J.

“…Aims/hypothesis Sodium–glucose cotransporter (SGLT) 2 inhibitors constitute a new class of glucose-lowering drugs, but they increase glucagon secretion, which…”
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Distribution and Stimulus Secretion Coupling of Enteroendocrine Cells along the Intestinal Tract by Adriaenssens, Alice E, Reimann, Frank, Gribble, Fiona M

“…The enteroendocrine system of the gut acts both locally and peripherally, regulating gastrointestinal function as well as metabolism, energy expenditure, and…”
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Hormonal regulation of H19 gene expression in prostate epithelial cells by Berteaux, N, Lottin, S, Adriaenssens, E, Van Coppenolle, F, Leroy, X, Coll, J, Dugimont, T, Curgy, J-J

“…The H19 gene is transcribed in an mRNA-like noncoding RNA. When tumors of various organs or cell types are considered, H19 oncogene or tumor-suppressor status…”
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Optimization of Measurement Conditions of an Energy Dispersive X-Ray Fluorescence Spectrometer with High-Energy Polarized Beam Excitation for Analysis of Aerosol Filters by Spolnik, Z., Belikov, K., Van Meel, K., Adriaenssens, E., De Roeck, F., Van Grieken, R.

“…A new commercial energy dispersive X-ray fluorescence spectrometer (EDXRF), applying a three-dimensional geometry and high-energy excitation, was optimized for…”
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