Search Results - "ADOLFSEN, Kristin J"

Improvement of a synthetic live bacterial therapeutic for phenylketonuria with biosensor-enabled enzyme engineering by Adolfsen, Kristin J., Callihan, Isolde, Monahan, Catherine E., Greisen, Per Jr, Spoonamore, James, Momin, Munira, Fitch, Lauren E., Castillo, Mary Joan, Weng, Lindong, Renaud, Lauren, Weile, Carl J., Konieczka, Jay H., Mirabella, Teodelinda, Abin-Fuentes, Andres, Lawrence, Adam G., Isabella, Vincent M.

“…In phenylketonuria (PKU) patients, a genetic defect in the enzyme phenylalanine hydroxylase (PAH) leads to elevated systemic phenylalanine (Phe), which can…”
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A Kinetic Platform to Determine the Fate of Hydrogen Peroxide in Escherichia coli by Adolfsen, Kristin J, Brynildsen, Mark P

“…Hydrogen peroxide (H2O2) is used by phagocytic cells of the innate immune response to kill engulfed bacteria. H2O2 diffuses freely into bacteria, where it can…”
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Transcriptional Regulation Contributes to Prioritized Detoxification of Hydrogen Peroxide over Nitric Oxide by Adolfsen, Kristin J, Chou, Wen Kang, Brynildsen, Mark P

“…Hydrogen peroxide (H O ) and nitric oxide (NO·) are toxic metabolites that immune cells use to attack pathogens. These antimicrobials can be present at the…”
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Futile cycling increases sensitivity toward oxidative stress in Escherichia coli by Adolfsen, Kristin J., Brynildsen, Mark P.

“…Reactive oxygen species (ROS) are toxic molecules utilized by the immune system to combat invading pathogens. Recent evidence suggests that inefficiencies in…”
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Deciphering nitric oxide stress in bacteria with quantitative modeling by Robinson, Jonathan L, Adolfsen, Kristin J, Brynildsen, Mark P

“…Highlights • NO detoxification and repair have been linked to virulence in many pathogens. • NO and its derivatives are broadly reactive and elicit a…”
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Antimicrobial Sand via Adsorption of Cationic Moringa oleifera Protein by Jerri, Huda A, Adolfsen, Kristin J, McCullough, Lauren R, Velegol, Darrell, Velegol, Stephanie B

“…Moringa oleifera (Moringa) seeds contain a natural cationic protein (MOCP) that can be used as an antimicrobial flocculant for water clarification. Currently,…”
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An integrated network analysis identifies how ArcAB enables metabolic oscillations in the nitric oxide detoxification network of Escherichia coli by Sacco, Sarah A., Adolfsen, Kristin J., Brynildsen, Mark P.

“…The virulences of many pathogens depend on their abilities to detoxify the immune antimicrobial nitric oxide (NO•). The functions of bacterial NO•…”
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A Kinetic Platform to Determine the Fate of Hydrogen Peroxide in Escherichia coli: e1004562 by Adolfsen, Kristin J, Brynildsen, Mark P

“…Hydrogen peroxide (H2O2) is used by phagocytic cells of the innate immune response to kill engulfed bacteria. H2O2 diffuses freely into bacteria, where it can…”
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PSV-10 Vaccination of beef cattle to reduce enteric methane emissions by Muntari, Musah, Arciero, Brigid R, Kuhn, Chene, Mulcock, Kate, Smith, Damon, Poliakiwski, Brette, O’Reilly, Keara, Jiménez, Odile Polanco, Bickmeier, Jeff, Kimler, Sara, Sullivan, John, Radulovic, Zeljko, Holland, Laura Z, Falk, Taylor A, Allen, Caitlin, Fitch, Lauren E, Spoonamore, James, Adolfsen, Kristin J, Carstens, Gordon E, Pohler, Ky G, Lamb, Cliff C, Dunn, Matthew R

“…Livestock methane (CH4) emissions total over 3 billion tonnes per year of carbon dioxide equivalents (CO2e) and are responsible for approximately 6% of total…”
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Antimicrobial Sand via Adsorption of Cationic Moringa oleifera Protein: BIOINSPIRED ASSEMBLIES AND INTERFACES by JERRI, Huda A, ADOLFSEN, Kristin J, MCCULLOUGH, Lauren R, VELEGOL, Darrell, VELEGOL, Stephanie B

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Toward ROS-potentiating anti-infectives: integrated computational and experimental analyses of bacterial ROS metabolism by Adolfsen, Kristin J

“…Antibiotic resistance is a growing public health concern, and existing approaches to antibiotic discovery are unable to keep pace with the decline of effective…”
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