Search Results - "ADLER, SHARON"

Diabetic Kidney Disease by Tong, Lili, Adler, Sharon G

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JAK1/JAK2 inhibition by baricitinib in diabetic kidney disease: results from a Phase 2 randomized controlled clinical trial by Tuttle, Katherine R, Brosius, 3rd, Frank C, Adler, Sharon G, Kretzler, Matthias, Mehta, Ravindra L, Tumlin, James A, Tanaka, Yoshiya, Haneda, Masakazu, Liu, Jiajun, Silk, Maria E, Cardillo, Tracy E, Duffin, Kevin L, Haas, Joseph V, Macias, William L, Nunes, Fabio P, Janes, Jonathan M

“…Inflammation signaled by Janus kinases (JAKs) promotes progression of diabetic kidney disease (DKD). Baricitinib is an oral, reversible, selective inhibitor of…”
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Comprehensive approach to diabetic nephropathy by Satirapoj, Bancha, Adler, Sharon G

“…Abstract Diabetic nephropathy (DN) is a leading cause of mortality and morbidity in patients with diabetes. This complication reflects a complex…”
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Chronic kidney disease, hypovitaminosis D, and mortality in the United States by Mehrotra, Rajnish, Kermah, Dulcie A., Salusky, Isidro B., Wolf, Myles S., Thadhani, Ravi I., Chiu, Yi-Wen, Martins, David, Adler, Sharon G., Norris, Keith C.

“…Low serum 25-hydroxy vitamin D (25OHD) predicts a higher cardiovascular risk in the general population. Because patients with chronic kidney disease are more…”
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Diabetic kidney disease treatment: new perspectives by Tong, Li-Li, Adler, Sharon G

“…Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease and end-stage kidney disease worldwide, as the obesity epidemic and the burden of…”
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Phase 1 Study of Anti-CTGF Monoclonal Antibody in Patients with Diabetes and Microalbuminuria by Adler, Sharon G., Schwartz, Sherwyn, Williams, Mark E., Arauz-Pacheco, Carlos, Bolton, Warren K., Lee, Tyson, Li, Dongxia, Neff, Thomas B., Urquilla, Pedro R., Sewell, K. Lea

“…This report summarizes the first phase 1 trial treating patients with microalbuminuric diabetic kidney disease (DKD) using FG-3019, a human monoclonal antibody…”
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The relatively poor correlation between random and 24-hour urine protein excretion in patients with biopsy-proven glomerular diseases by Hogan, Marie C, Reich, Heather N, Nelson, Peter J, Adler, Sharon G, Cattran, Daniel C, Appel, Gerald B, Gipson, Debbie S, Kretzler, Matthias, Troost, Jonathan P, Lieske, John C

“…Random urine protein creatinine ratios are used to estimate 24-hour urine protein excretion, which is considered a diagnostic gold standard. However, few…”
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Prevalence and Management of Diabetic Nephropathy in Western Countries by Satirapoj, Bancha, Adler, Sharon G.

“…Background: Diabetic nephropathy (DN) often results in end-stage renal disease, and this is the most common reason for initiation of dialysis in the United…”
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MYH9 is associated with nondiabetic end-stage renal disease in African Americans by Schelling, Jeffrey R, Thornley-Brown, Denyse, Kimmel, Paul L, Klag, Michael J, Li, Man, Patterson, Nick, Kohn, Orly F, Weir, Matthew R, Coresh, Josef, Abboud, Hanna E, Divers, Jasmin, Nicholas, Susanne B, Knowler, William C, Kramp, Kristopher, Berthier-Schaad, Yvette, Tandon, Arti, Iyengar, Sudha K, Sadler, John H, Sedor, John R, Reich, David, Smith, Michael W, Freedman, Barry I, Winkler, Cheryl A, Adler, Sharon G, Parekh, Rulan S, Powe, Neil R, Meoni, Lucy A, Fink, Nancy E, Pahl, Madeleine V, Kao, W H Linda, Leehey, David J

“…Linda Kao and colleagues use admixture mapping to identify risk variants in MYH9 associated with nondiabetic end-stage renal disease in African Americans. The…”
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Dual therapy with an angiotensin receptor blocker and a JAK1/2 inhibitor attenuates dialysate-induced angiogenesis and preserves peritoneal membrane structure and function in an experimental CKD rat model by Zhang, Pei, Miyata, Kana N, Nast, Cynthia C, LaPage, Janine A, Mahoney, Madisyn, Nguyen, Sonny, Khan, Kamran, Wu, Qiaoyuan, Adler, Sharon G, Dai, Tiane

“…Background: Peritoneal dialysis (PD) is limited by reduced efficacy over time. We previously showed that a Janus kinase 1/2 inhibitor (JAK1/2i) reduced…”
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Effects of Minocycline on Urine Albumin, Interleukin-6, and Osteoprotegerin in Patients with Diabetic Nephropathy: A Randomized Controlled Pilot Trial by Shah, Anuja P, Shen, Jenny I, Wang, Ying, Tong, Lili, Pak, Youngju, Andalibi, Ali, LaPage, Janine A, Adler, Sharon G

“…We tested minocycline as an anti-proteinuric adjunct to renin-angiotensin-aldosterone system inhibitors (RAASi) in diabetic nephropathy (DN) and measured…”
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Periostin: novel tissue and urinary biomarker of progressive renal injury induces a coordinated mesenchymal phenotype in tubular cells by SATIRAPOJ, Bancha, YING WANG, CHAMBERLIN, Mina P, TIANE DAI, LAPAGE, Janine, PHILLIPS, Lynetta, NAST, Cynthia C, ADLER, Sharon G

“…Periostin acts as an adhesion molecule during bone formation. Knowledge of its expression in kidney injury is scant. We investigated periostin function and…”
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Coronary artery calcification and mortality in diabetic patients with proteinuria by Chiu, Yi-Wen, Adler, Sharon G., Budoff, Matthew J., Takasu, Junichiro, Ashai, Jamila, Mehrotra, Rajnish

“…Vascular calcification is one of the mechanisms mediating the higher mortality risk associated with the hyperphosphatemia of chronic kidney disease. Though…”
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Genome-Wide Association of CKD Progression: The Chronic Renal Insufficiency Cohort Study by Parsa, Afshin, Kanetsky, Peter A, Xiao, Rui, Gupta, Jayanta, Mitra, Nandita, Limou, Sophie, Xie, Dawei, Xu, Huichun, Anderson, Amanda Hyre, Ojo, Akinlolu, Kusek, John W, Lora, Claudia M, Hamm, L Lee, He, Jiang, Sandholm, Niina, Jeff, Janina, Raj, Dominic E, Böger, Carsten A, Bottinger, Erwin, Salimi, Shabnam, Parekh, Rulan S, Adler, Sharon G, Langefeld, Carl D, Bowden, Donald W, Groop, Per-Henrik, Forsblom, Carol, Freedman, Barry I, Lipkowitz, Michael, Fox, Caroline S, Winkler, Cheryl A, Feldman, Harold I

“…The rate of decline of renal function varies significantly among individuals with CKD. To understand better the contribution of genetics to CKD progression, we…”
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The International Society of Glomerular Disease: Building the Future of Glomerular Medicine by Damashek, Laurel J., Adler, Sharon G., Tarnoff, Joshua M., Huber, Tobias B.

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Chronic interstitial nephritis in agricultural communities and pre-eclampsia: Is there a link? by Orantes, Carlos, Olano, Claudia, Salinas, Carlos, Guevara, Nehemias, Vela, Xavier, Adler, Sharon, Pahl, Madeleine, Barba, Lilly, Nast, Cynthia C

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Exercise capacity as a predictor of survival among ambulatory patients with end-stage renal disease by Sietsema, Kathy E., Amato, Antonino, Adler, Sharon G., Brass, Eric P.

“…Exercise capacity as a predictor of survival among ambulatory patients with end-stage renal disease. Exercise capacity is reduced in end-stage renal disease…”
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Heritability of the Severity of Diabetic Retinopathy: The FIND-Eye Study by Arar, Nedal H, Freedman, Barry I, Adler, Sharon G, Iyengar, Sudha K, Chew, Emily Y, Davis, Mathew D, Satko, Scott G, Bowden, Donald W, Duggirala, Ravi, Elston, Robert C, Guo, Xiuxing, Hanson, Robert L, Igo, Robert P., Jr, Ipp, Eli, Kimmel, Paul L, Knowler, William C, Molineros, Julio, Nelson, Robert G, Pahl, Madeleine V, Quade, Shannon R. E, Rasooly, Rebekah S, Rotter, Jerome I, Saad, Mohammed F, Scavini, Marina, Schelling, Jeffrey R, Sedor, John R, Shah, Vallabh O, Zager, Philip G, Abboud, Hanna E, on behalf of Family Investigation of Nephropathy and Diabetes Research Group

“…Diabetic retinopathy (DR) and diabetic nephropathy (DN) are serious microvascular complications of diabetes mellitus. Correlations between severity of DR and…”
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Erratum to Gene Set Enrichment Analyses Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy. Am J Ophthalmol 2022;233:111-123 by Sobrin, Lucia, Susarla, Gayatri, Stanwyck, Lynn, Rouhana, John M., Li, Ashley, Pollack, Samuela, Igo, Robert P., Jensen, Richard A., Li, Xiaohui, Ng, Maggie C.Y., Smith, Albert V., Kuo, Jane Z., Taylor, Kent D., Freedman, Barry I., Bowden, Donald W., Penman, Alan, Chen, Ching J., Craig, Jamie E., Adler, Sharon G., Chew, Emily Y., Cotch, Mary Frances, Yaspan, Brian, Mitchell, Paul, Wang, Jie Jin, Klein, Barbara E.K., Wong, Tien Y., Rotter, Jerome I., Burdon, Kathyrn P., Iyengar, Sudha K., Segrè, Ayellet V.

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Gaining Ground in Glomerular Diseases by Adler, Sharon G., Nast, Cynthia C.

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