Search Results - "ADELSBERGER, Jennifer K"
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EVALUATION OF MICRODOSING STRATEGIES FOR STUDIES IN PRECLINICAL DRUG DEVELOPMENT: DEMONSTRATION OF LINEAR PHARMACOKINETICS IN DOGS OF A NUCLEOSIDE ANALOG OVER A 50-FOLD DOSE RANGE
Published in Drug metabolism and disposition (01-11-2004)“…The technique of accelerator mass spectrometry (AMS) was validated successfully and used to study the pharmacokinetics and disposition in dogs of a preclinical…”
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An in vivo microdialysis coupled with liquid chromatography/tandem mass spectrometry study of cortisol metabolism in monkey adipose tissue
Published in Analytical biochemistry (15-10-2008)“…It is postulated that elevated tissue concentrations of cortisol may be associated with the development of metabolic syndrome, obesity, and type 2 diabetes…”
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Population pharmacokinetic modeling for enterohepatic recirculation in Rhesus monkey
Published in European journal of pharmaceutical sciences (01-10-2005)“…Enterohepatic recirculation (EHR) occurs via biliary excretion and intestinal reabsorption of a drug. Drug recycling through EHR can lead to a change in…”
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