Search Results - "ADEDEJI, Adebayo"

Modeling Preclinical Cancer Studies under Physioxia to Enhance Clinical Translation by Adebayo, Adedeji K, Nakshatri, Harikrishna

“…Oxygen (O2) plays a key role in cellular homeostasis. O2 levels are tightly regulated in vivo such that each tissue receives an optimal amount to maintain…”
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Nexus between PI3K/AKT and Estrogen Receptor Signaling in Breast Cancer by Khatpe, Aditi S, Adebayo, Adedeji K, Herodotou, Christopher A, Kumar, Brijesh, Nakshatri, Harikrishna

“…Signaling from estrogen receptor alpha (ERα) and its ligand estradiol (E2) is critical for growth of ≈70% of breast cancers. Therefore, several drugs that…”
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Single-nucleus chromatin accessibility and transcriptomic map of breast tissues of women of diverse genetic ancestry by Bhat-Nakshatri, Poornima, Gao, Hongyu, Khatpe, Aditi S, Adebayo, Adedeji K, McGuire, Patrick C, Erdogan, Cihat, Chen, Duojiao, Jiang, Guanglong, New, Felicia, German, Rana, Emmert, Lydia, Sandusky, George, Storniolo, Anna Maria, Liu, Yunlong, Nakshatri, Harikrishna

“…Single-nucleus analysis allows robust cell-type classification and helps to establish relationships between chromatin accessibility and cell-type-specific gene…”
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Mutant RAS-driven Secretome Causes Skeletal Muscle Defects in Breast Cancer by Wang, Ruizhong, Khatpe, Aditi S, Kumar, Brijesh, Mang, Henry Elmer, Batic, Katie, Adebayo, Adedeji K, Nakshatri, Harikrishna

“…Cancer-induced skeletal muscle defects differ in severity between individuals with the same cancer type. Cancer subtype-specific genomic aberrations are…”
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Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies by Adebayo, Adedeji K., Bhat-Nakshatri, Poornima, Davis, Christopher, Angus, Steven P., Erdogan, Cihat, Gao, Hongyu, Green, Nick, Kumar, Brijesh, Liu, Yunlong, Nakshatri, Harikrishna

“…Most cells in solid tumors are exposed to oxygen levels between 0.5% and 5%. We developed an approach that allows collection, processing, and evaluation of…”
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CHEMICAL ANALYSIS OF WATER SOURCED FROM ODO ONA RIVER, IBADAN, SOUTH-WESTERN NIGERIA by NKESHITA, FIDELIS, ADEKUNLE, ADEBOLA, ADEDEJI, ADEBAYO

“…The water samples were collected at three different periods of the year from locations around the Oluyole Estate Industrial hub housing many industries and…”
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Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity by Kumar, Brijesh, Adebayo, Adedeji K, Prasad, Mayuri, Capitano, Maegan L, Wang, Ruizhong, Bhat-Nakshatri, Poornima, Anjanappa, Manjushree, Simpson, Edward, Chen, Duojiao, Liu, Yunlong, Schilder, Jeanne M, Colter, Austyn B, Maguire, Callista, Temm, Constance J, Sandusky, George, Doud, Emma H, Wijeratne, Aruna B, Mosley, Amber L, Broxmeyer, Hal E, Nakshatri, Harikrishna

“…Preclinical studies of primary cancer cells are typically done after tumors are removed from patients or animals at ambient atmospheric oxygen (O , ~21%)…”
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Role of apoptotic protease activating factor-1 in CD4+ depletion during HIV progression by Garuba, Wasiu O, Adedeji, Adebayo L, Adedokun, Kamoru A, Ayelagbe, Olubunmi G, Abdullahi, Idris N, Munirudeen, Ibrahim

“…This study investigates the role of Apoptotic Protease Activating Factor-1 (APAF-1) in CD4+ cell depletion among human immunodeficiency virus (HIV) patients…”
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Clofibrate, a PPAR‐α agonist, abrogates sodium fluoride‐induced neuroinflammation, oxidative stress, and motor incoordination via modulation of GFAP/Iba‐1/anti‐calbindin signaling pathways by Oyagbemi, Ademola A., Adebiyi, Olamide E., Adigun, Kabirat O., Ogunpolu, Blessing S., Falayi, Olufunke O., Hassan, Fasilat O., Folarin, Oluwabusayo R., Adebayo, Adedeji K., Adejumobi, Olumuyiwa A., Asenuga, Ebunoluwa R., Ola‐Davies, Olufunke E., Omobowale, Temidayo O., Olopade, James O., Saba, Adebowale B., Adedapo, Adeolu A., Nkadimeng, Sanah M., McGaw, Lyndy J., Oguntibeju, Oluwafemi O., Yakubu, Momoh A.

“…Fluoride is an environmental contaminant that is ubiquitously present in air, water, and soil. It is commonly added in minute quantity to drinking water,…”
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Epidemiology of influenza in Nigeria: A secondary analysis of the sentinel surveillance data in Nigeria from 2010 – 2020 by Akano, Adejoke, Sadauki, Aisha Habib, Adelabu, Adeyemi Mark, Malgwi, Arhyel, Fagbola, Motunrayo, Ogunbode, Oladipo, Usman, Aishat, Ameh, Celestine, Balogun, Muhammad Shakir, Ilori, Elsie, Badaru, Sikiru, Adetunji, Adewusi, Adebayo, Adedeji, Mba, Nwando, Iniobong, Akanimo, Eze, Emmanuel, Akerele, Isaac, Grema, Bukar, Sodipo, Oluwajimi, Enemuo, Emeka, Ochu, Chinwe, Ihekweazu, Chikwe, Adetifa, Ifedayo

“…Influenza is a leading cause of morbidity and mortality globally. Little is known of the true burden and epidemiology of influenza in Africa. Nigeria has a…”
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Managing Change: Transition from the Traditional Bureaucratic Practices to E-Government by Oluwalogbon, Leke Abraham, Adedeji, Adebayo

“…In line with international best practice and public demand for a more efficient and responsive public service, Nigeria – like many other countries – gradually…”
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Influenza surveillance capacity improvements in Africa during 2011‐2017 by Igboh, Ledor S., McMorrow, Meredith, Tempia, Stefano, Emukule, Gideon O., Talla Nzussouo, Ndahwouh, McCarron, Margaret, Williams, Thelma, Weatherspoon, Vashonia, Moen, Ann, Fawzi, Derrar, Njouom, Richard, Nakoune, Emmanuel, Dauoda, Coulibaly, Kavunga‐Membo, Hugo, Okeyo, Mary, Heraud, Jean‐Michel, Mambule, Ivan Kiggundu, Sow, Samba Ousmane, Tivane, Almiro, Lagare, Adamou, Adebayo, Adedeji, Dia, Ndongo, Mmbaga, Vida, Maman, Issaka, Lutwama, Julius, Simusika, Paul, Walaza, Sibongile, Mangtani, Punam, Nguipdop‐Djomo, Patrick, Cohen, Cheryl, Azziz‐Baumgartner, Eduardo

“…Background Influenza surveillance helps time prevention and control interventions especially where complex seasonal patterns exist. We assessed influenza…”
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Epidemiology of influenza in West Africa after the 2009 influenza A(H1N1) pandemic, 2010-2012 by Talla Nzussouo, Ndahwouh, Duque, Jazmin, Adedeji, Adebayo Abel, Coulibaly, Daouda, Sow, Samba, Tarnagda, Zekiba, Maman, Issaka, Lagare, Adamou, Makaya, Sonia, Elkory, Mohamed Brahim, Kadjo Adje, Herve, Shilo, Paul Alhassan, Tamboura, Boubou, Cisse, Assana, Badziklou, Kossi, Maïnassara, Halima Boubacar, Bara, Ahmed Ould, Keita, Adama Mamby, Williams, Thelma, Moen, Ann, Widdowson, Marc-Alain, McMorrow, Meredith

“…Over the last decade, capacity for influenza surveillance and research in West Africa has strengthened. Data from these surveillance systems showed influenza…”
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Intergovernmental relations and national education policy implementation in Lagos State, Nigeria by Adedeji, Adebayo O.

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Characterisation of heart failure with normal ejection fraction in a tertiary hospital in Nigeria by Adebayo, Adedeji K, Adebiyi, Adewole A, Oladapo, Olulola O, Ogah, Okechukwu S, Aje, Akinyemi, Ojji, Dike B, Falase, Ayodele O

“…The study aimed to determine the frequency and characteristics of heart failure with normal EF in a native African population with heart failure. It was a…”
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Gestational perturbation of homocysteine metabolism reduces Spina bifida prevalence in Osun State, Nigeria by Akanni, Emmauel Olufemi, Adedeji, Adebayo Lawrence, Oyinlola, Oyindamola Nike, Azeez, Raufu Taiwo, Akinbo, David Bolaji

“…Background: Elevated maternal homocysteine concentration has been described as a consequence of disruptions in methionine and/or folate metabolism which is…”
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Evaluation of nine HIV rapid test kits to develop a national HIV testing algorithm in Nigeria by Bassey, Orji, Bond, Kyle, Adedeji, Adebayo, Oke, Odafen, Abubakar, Ado, Yakubu, Kachiro, Jelpe, Tapdiyel, Akintunde, Ezekiel, Ikani, Patrick, Ogundiran, Adeniyi, Onoja, Ali, Kawu, Issa, Ikwulono, Gabriel, Saliu, Idris, Nwanyawu, Okey, Deyde, Varough

“…Background: Non-cold chain-dependent HIV rapid testing has been adopted in many resource-constrained nations as a strategy for reaching out to populations. HIV…”
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Echocardiographic partition values and prevalence of left ventricular hypertrophy in hypertensive Nigerians by Adebiyi, Adewole A, Ogah, Okechukwu S, Aje, Akinyemi, Ojji, Dike B, Adebayo, Adedeji K, Oladapo, Olulola O, Falase, Ayodele O

“…Left ventricular hypertrophy (LVH) is a well known independent risk factor for cardiovascular events. It has been shown that combination of left ventricular…”
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Trends in Department of Defense Support Costs by Adedeji, Adebayo

“…Funding for support functions -- such as maintenance, training, and management is higher today than during the 1980s. Rising support costs could signal…”
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Blood pressure control and left ventricular hypertrophy in hypertensive Nigerians by Salako, Babatunde L, Ogah, Okechukwu S, Adebiyi, Adewole A, Oladapo, Olulola O, Aje, Akinyemi, Adebayo, Adedeji K, Ojji, Dike B, Ipadeola, Arinola, Nwafor, Chibuike E

“…Hypertension is a disease characterized by end-organ complications, leading to high morbidity and mortality in many cases. People with untreated or…”
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