Search Results - "ADAMS, Dianne M"

Boron-Containing Folate Receptor-Targeted Liposomes as Potential Delivery Agents for Neutron Capture Therapy by Pan, Xing Q, Wang, Huaqing, Shukla, Supriya, Sekido, Masaru, Adams, Dianne M, Tjarks, Werner, Barth, Rolf F, Lee, Robert J

“…Boron neutron capture therapy (BNCT) depends on the selective delivery of a sufficient number of 10B atoms to tumor cells to sustain a lethal 10B(n,α)7Li…”
Get full text

Boronated starburst dendrimer-monoclonal antibody immunoconjugates: Evaluation as a potential delivery system for neutron capture therapy by Barth, Rolf F, Adams, Dianne M, Soloway, Albert H, Alam, Fazlul, Darby, Michael V

“…Boron neutron capture therapy (BNCT) is based on the nuclear capture reaction that occurs when boron-10, a stable isotope, is irradiated with low-energy or…”
Get full text

Synthesis and Biological Evaluation of Boron-Containing Polyamines as Potential Agents for Neutron Capture Therapy of Brain Tumors by Zhuo, Jin-Cong, Cai, Jianping, Soloway, Albert H, Barth, Rolf F, Adams, Dianne M, Ji, Weihua, Tjarks, Werner

“…New boron-containing spermidine/spermine (SPD/SPM) analogues have been synthesized:  N 5-[4-(2-aminoethyl-o-carboranyl)butyl] and N…”
Get full text

Boronated Epidermal Growth Factor as a Potential Targeting Agent for Boron Neutron Capture Therapy of Brain Tumors by Capala, Jacek, Barth, Rolf F, Bendayan, Moïse, Lauzon, Michel, Adams, Dianne M, Soloway, Albert H, Fenstermaker, Robert A, Carlsson, Jörgen

“…In order for boron neutron capture therapy (BNCT) to be successful, a large number (∼109) of 10B atoms must be delivered to each cancer cell in order to…”
Get full text

Boron-Containing Polyamines as DNA Targeting Agents for Neutron Capture Therapy of Brain Tumors:  Synthesis and Biological Evaluation by Cai, Jianping, Soloway, Albert H, Barth, Rolf F, Adams, Dianne M, Hariharan, Joya R, Wyzlic, Iwona M, Radcliffe, Krista

“…Three series of new boron-containing spermidine/spermine (SPD/SPM) analogues have been synthesized:  N - and N 5-(4-carboranylbutyl) SPD/SPM derivatives…”
Get full text

Synthesis and in vitro evaluation of boronated uridine and glucose derivatives for boron neutron capture therapy by Tjarks, Werner, Anisuzzaman, Abul K. M, Liu, Liang, Soloway, Albert H, Barth, Rolf F, Perkins, Douglas J, Adams, Dianne M

“…The following boron-containing nucleoside and glucose derivatives have been synthesized as potential boron delivery agents for boron neutron capture therapy…”
Get full text

Determination of boron in tissues and cells using direct-current plasma atomic emission spectroscopy by Barth, Rolf F, Adams, Dianne M, Soloway, Albert H, Mechetner, Eugene B, Alam, Fazlul, Anisuzzaman, Abul K. M

“…We have developed a safe, simple, and efficient method for boron determination by means of direct-current plasma atomic emission spectroscopy. Tissues were…”
Get full text

Convection-enhanced delivery of boronated epidermal growth factor for molecular targeting of EGF receptor-positive gliomas by WEILIAN YANG, BARTH, Rolf F, ADAMS, Dianne M, CIESIELSKI, Michael J, FENSTERMAKER, Robert A, SHUKLA, Supriya, TJARKS, Werner, CALIGIURI, Michael A

“…Convection enhanced delivery (CED) is potentially a powerful method to improvethe targeting of macromolecules to the central nervous system by applying a…”
Get full text

Molecular targeting of the epidermal growth factor receptor for neutron capture therapy of gliomas by BARTH, Rolf F, WEILIAN YANG, CODERRE, Jeffrey A, ADAMS, Dianne M, ROTARU, Joan H, SHUKLA, Supriya, SEKIDO, Masaru, TJARKS, Werner, FENSTERMAKER, Robert A, CIESIELSKI, Michael, NAWROCKY, Marta M

“…Success of boron neutron capture therapy (BNCT) is dependent on cellular and molecular targeting of sufficient amounts of boron-10 to sustain a lethal (10)B…”
Get full text

Boron neutron capture therapy: linkage of a boronated macromolecule to monoclonal antibodies directed against tumor-associated antigens by Alam, Fazlul, Soloway, Albert H, Barth, Rolf F, Mafune, Naoki, Adams, Dianne M, Knoth, Walter H

“…Two new protein-binding polyhedral boron derivatives, isocyanatoundecahydro-closo-dodecaborate(2-) (1) and…”
Get full text

Intratumoral delivery of boronated epidermal growth factor for neutron capture therapy of brain tumors by YANG, W, BARTH, R. F, ADAMS, D. M, SOLOWAY, A. H

“…The gene for epidermal growth factor receptor (EGFR) is amplified or overexpressed in high-grade gliomas but is low or undetectable in normal brain. Recently,…”
Get full text

Synthesis and Biological Evaluation of Boron-Containing Polyamines as Potential Agents for Neutron Capture Therapy of Brain Tumors by Zhuo, Jin-Cong, Cai, Jianping, Soloway, Albert H, Barth, Rolf F, Adams, Dianne M, Ji, Weihua, Tjarks, Werner

Get full text

Boron neutron capture therapy of brain tumors: biodistribution, pharmacokinetics, and radiation dosimetry sodium borocaptate in patients with gliomas by Goodman, J H, Yang, W, Barth, R F, Gao, Z, Boesel, C P, Staubus, A E, Gupta, N, Gahbauer, R A, Adams, D M, Gibson, C R, Ferketich, A K, Moeschberger, M L, Soloway, A H, Carpenter, D E, Albertson, B J, Bauer, W F, Zhang, M Z, Wang, C C

“…The purpose of this study was to obtain tumor and normal brain tissue biodistribution data and pharmacokinetic profiles for sodium borocaptate (Na2B12H11SH)…”
Get full text

Comparative in vitro evaluation of dequalinium B, a new boron carrier for neutron capture therapy (NCT) by Adams, D M, Ji, W, Barth, R F, Tjarks, W

“…A boronated derivative of dequalinium, a delocalized lipophilic cation (DLC), was synthesized as a potential boron carrier for the selective targeting of…”
Get more information

Evaluation of systemically administered radiolabeled epidermal growth factor as a brain tumor targeting agent by YANG, Weilian, BARTH, Rolf F, LEVEILLE, Renee, ADAMS, Dianne M, CIESIELSKI, Michael, FENSTERMAKER, Robert A, CAPALA, Jacek

“…We have previously reported a method for labeling epidermal growth factor (EGF) with technetium-99m and have shown that 99mTc-EGF localized in EGF receptor (R)…”
Get full text

In vivo evaluation of phosphorous-containing derivatives of dodecahydro-closo-dodecaborate for boron neutron capture therapy of gliomas and sarcomas by Tjarks, W, Barth, R F, Rotaru, J H, Adams, D M, Yang, W, Kultyshev, R G, Forrester, J, Barnum, B A, Soloway, A H, Shore, S G

“…The in vivo uptake of dodecahydro-closo-dodecaborate derivatives substituted with phosphate- and bisphosphonate groups was evaluated in two different…”
Get more information

Boron Neutron Capture Therapy of Brain Tumors: Biodistribution, Pharmacokinetics, and Radiation Dosimetry of Sodium Borocaptate in Patients with Gliomas by Goodman, Joseph H., Yang, Weilian, Barth, Rolf F., Gao, Zhixian, Boesel, Carl P., Staubus, Alfred E., Gupta, Nilendu, Gahbauer, Reinhard A., Adams, Dianne M., Gibson, Christopher R., Ferketich, Amy K., Moeschberger, Melvin L., Soloway, Albert H., Carpenter, David E., Albertson, Brent J., Bauer, William F., Zhang, Mao Zhi, Wang, Chung Cheng

Get full text

Distinct and non-cross-reactive epitopes are recognized on B16 melanoma by LAK cells and anti-B16 monoclonal antibodies by Tzeng, J J, Barth, R F, Johnson, C W, Adams, D M

“…Two rat anti-B16 melanoma monoclonal antibodies (MoAb), designated IB16-6 and IB16-8, recognize an epitope expressed with high density on the surface of B16…”
Get more information

Bispecific antibodies as targeting agents for boron neutron capture therapy of brain tumors by Liu, L, Barth, R F, Adams, D M, Soloway, A H, Reisfeld, R A

“…Boron neutron capture therapy (BNCT) is based on the nuclear reaction that occurs when boron-10, a stable isotope, is irradiated with low energy (< or = 0.025…”
Get more information

Limits of sensitivity for the radioimmunodetection of colon cancer by means of a hand held gamma probe by Oredipe, O A, Barth, R F, Tuttle, S E, Adams, D M, Sautins, I, Bucci, D M, Mojzisik, C M, Hinkle, G H, Jewell, S, Steplewski, Z

“…This study was undertaken to define the limits for the radioimmunodetection of minimal deposits of colorectal cancer cells using a hand held gamma probe. 125I…”
Get more information