Search Results - "ADAMS, Christopher"

UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor by Kopp, Megan C., Larburu, Natacha, Durairaj, Vinoth, Adams, Christopher J., Ali, Maruf M. U.

“…BiP is a major endoplasmic reticulum (ER) chaperone and is suggested to act as primary sensor in the activation of the unfolded protein response (UPR). How BiP…”
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Proteomics of Primary Cilia by Proximity Labeling by Mick, David U., Rodrigues, Rachel B., Leib, Ryan D., Adams, Christopher M., Chien, Allis S., Gygi, Steven P., Nachury, Maxence V.

“…While cilia are recognized as important signaling organelles, the extent of ciliary functions remains unknown because of difficulties in cataloguing proteins…”
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Vibrational Autodetachment from Anionic Nitroalkane Chains: From Molecular Signatures to Thermionic Emission by Adams, Christopher L, Hansen, Klavs, Weber, J. Mathias

“…We report the kinetic energy distributions in electron autodetachment from nitroethane, 1-nitropropane, and 1-nitrobutane anions upon laser excitation of CH…”
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Future development of plastic and reconstructive surgery in Australasia by Adams, Christopher

“…Plastic surgeons and plastic surgery services must be visible, accessible and available for patients in regions and across metropolitan centres if the…”
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A Spatial Interactome Reveals the Protein Organization of the Algal CO2-Concentrating Mechanism by Mackinder, Luke C.M., Chen, Chris, Leib, Ryan D., Patena, Weronika, Blum, Sean R., Rodman, Matthew, Ramundo, Silvia, Adams, Christopher M., Jonikas, Martin C.

“…Approximately one-third of global CO2 fixation is performed by eukaryotic algae. Nearly all algae enhance their carbon assimilation by operating a…”
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Arthroscopic Superior Capsular Reconstruction for Treatment of Massive Irreparable Rotator Cuff Tears by Hirahara, Alan M., M.D., F.R.C.S.C, Adams, Christopher R., M.D

“…Abstract Massive irreparable rotator cuff tears have been troublesome entities to treat, especially in younger patients. Few good options exist, leaving most…”
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Preliminary Results of Arthroscopic Superior Capsule Reconstruction with Dermal Allograft by Denard, Patrick J., Brady, Paul C., Adams, Christopher R., Tokish, John M., Burkhart, Stephen S.

“…The purpose of this study was to evaluate the short-term outcomes of arthroscopic superior capsule reconstruction (SCR) with dermal allograft for the treatment…”
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A Constructively Aligned First-Year Laboratory Course by Adams, Christopher J

“…The first-year undergraduate laboratory course in chemistry at the University of Bristol has been changed in an attempt to have students focus on learning…”
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Regularized sequence-context mutational trees capture variation in mutation rates across the human genome by Adams, Christopher J, Conery, Mitchell, Auerbach, Benjamin J, Jensen, Shane T, Mathieson, Iain, Voight, Benjamin F

“…Germline mutation is the mechanism by which genetic variation in a population is created. Inferences derived from mutation rate models are fundamental to many…”
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Subunit order of eukaryotic TRiC/CCT chaperonin by cross-linking, mass spectrometry, and combinatorial homology modeling by Kalisman, Nir, Adams, Christopher M, Levitt, Michael

“…The TRiC/CCT chaperonin is a 1-MDa hetero-oligomer of 16 subunits that assists the folding of proteins in eukaryotes. Low-resolution structural studies…”
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Craniopharyngiomas by Karavitaki, Niki, Cudlip, Simon, Adams, Christopher B. T, Wass, John A. H

“…Craniopharyngiomas are rare, mainly sellar/parasellar, epithelial tumors diagnosed during childhood or adult life. Histologically, two primary subtypes have…”
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Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy by Kimura, Tomonori, Jia, Jingyue, Kumar, Suresh, Choi, Seong Won, Gu, Yuexi, Mudd, Michal, Dupont, Nicolas, Jiang, Shanya, Peters, Ryan, Farzam, Farzin, Jain, Ashish, Lidke, Keith A, Adams, Christopher M, Johansen, Terje, Deretic, Vojo

“…Autophagy is a process delivering cytoplasmic components to lysosomes for degradation. Autophagy may, however, play a role in unconventional secretion of…”
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Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease by Kunkel, Steven D, Elmore, Christopher J, Bongers, Kale S, Ebert, Scott M, Fox, Daniel K, Dyle, Michael C, Bullard, Steven A, Adams, Christopher M

“…Skeletal muscle Akt activity stimulates muscle growth and imparts resistance to obesity, glucose intolerance and fatty liver disease. We recently found that…”
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Role of the Transcription Factor ATF4 in the Anabolic Actions of Insulin and the Anti-anabolic Actions of Glucocorticoids by Adams, Christopher M.

“…In most mammalian cells, insulin and glucocorticoids promote anabolism and catabolism, respectively. Whereas the opposing effects of insulin and…”
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The Rotator Cuff and the Superior Capsule: Why We Need Both by Adams, Christopher R., M.D, DeMartino, Angelica M., M.S, Rego, George, M.P.H., P.A.-C, Denard, Patrick J., M.D, Burkhart, Stephen S., M.D

“…Abstract Tears of the rotator cuff are frequent. An estimated 250,000 to 500,000 repairs are performed annually in the United States. Rotator cuff repairs have…”
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Spending on new drug development by Adams, Christopher Paul, Brantner, Van Vu

“…This paper replicates DiMasi et al. (J. Health Econ. 2003; 22: 151-185; Drug Inf. J. 2004; 38: 211-223) estimates of expenditure on new drug development using…”
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Structure and Molecular Mechanism of ER Stress Signaling by the Unfolded Protein Response Signal Activator IRE1 by Adams, Christopher J, Kopp, Megan C, Larburu, Natacha, Nowak, Piotr R, Ali, Maruf M U

“…The endoplasmic reticulum (ER) is an important site for protein folding and maturation in eukaryotes. The cellular requirement to synthesize proteins within…”
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Intraspecific variation in stomatal traits, leaf traits and physiology reflects adaptation along aridity gradients in a South African shrub by Carlson, Jane E., Adams, Christopher A., Holsinger, Kent E.

“…Trait-environment relationships are commonly interpreted as evidence for local adaptation in plants. However, even when selection analyses support this…”
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Control of skeletal muscle atrophy in response to disuse: clinical/preclinical contentions and fallacies of evidence by Atherton, Philip J, Greenhaff, Paul L, Phillips, Stuart M, Bodine, Sue C, Adams, Christopher M, Lang, Charles H

“…Muscle wasting resulting wholly or in part from disuse represents a serious medical complication that, when prolonged, can increase morbidity and mortality…”
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mRNA Expression Signatures of Human Skeletal Muscle Atrophy Identify a Natural Compound that Increases Muscle Mass by Kunkel, Steven D., Suneja, Manish, Ebert, Scott M., Bongers, Kale S., Fox, Daniel K., Malmberg, Sharon E., Alipour, Fariborz, Shields, Richard K., Adams, Christopher M.

“…Skeletal muscle atrophy is a common and debilitating condition that lacks a pharmacologic therapy. To develop a potential therapy, we identified 63 mRNAs that…”
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