Search Results - "ADACHI, Masashi"

Long Range Functionalization of h‑BN Monolayer by Carbon Doping by Gao, Min, Adachi, Masashi, Lyalin, Andrey, Taketsugu, Tetsuya

“…Adsorption and catalytic activation of the molecular oxygen on the hexagonal boron nitride (h-BN) monolayer doped with carbon atom have been studied…”
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Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir by Imaoka, Tomoki, Kusuhara, Hiroyuki, Adachi, Masashi, Schuetz, John D, Takeuchi, Kenji, Sugiyama, Yuichi

“…Acyclic nucleotide phosphonates (adefovir, cidofovir, and tenofovir) are eliminated predominantly into the urine, and renal failure is their dose-limiting…”
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Real‐time in vivo dosimetry system based on an optical fiber‐coupled microsized photostimulable phosphor for stereotactic body radiation therapy by Yada, Ryuichi, Maenaka, Kazusuke, Miyamoto, Shuji, Okada, Go, Sasakura, Aki, Ashida, Motoi, Adachi, Masashi, Sato, Tatsuhiko, Wang, Tianyuan, Akasaka, Hiroaki, Mukumoto, Naritoshi, Shimizu, Yasuyuki, Sasaki, Ryohei

“…Purpose To develop an in vivo dosimeter system for stereotactic body radiation therapy (SBRT) that can perform accurate and precise real‐time measurements,…”
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Multiple Human Isoforms of Drug Transporters Contribute to the Hepatic and Renal Transport of Olmesartan, a Selective Antagonist of the Angiotensin II AT1-Receptor by YAMADA, Akihiro, MAEDA, Kazuya, ADACHI, Yasuhisa, ZHUOHAN HU, KUSUHARA, Hiroyuki, SUGIYAMA, Yuichi, KAMIYAMA, Emi, SUGIYAMA, Daisuke, KONDO, Tsunenori, SHIROYANAGI, Yoshiyuki, NAKAZAWA, Hayakazu, OKANO, Teruo, ADACHI, Masashi, SCHUETZ, John D

“…Olmesartan, a novel angiotensin II AT1-receptor antagonist, is excreted into both bile and urine, with minimal metabolism. Because olmesartan is a hydrophilic…”
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Mrp4 Confers Resistance to Topotecan and Protects the Brain from Chemotherapy by Leggas, Markos, Adachi, Masashi, Scheffer, George L., Sun, Daxi, Wielinga, Peter, Du, Guoqing, Mercer, Kelly E., Zhuang, Yanli, Panetta, John C., Johnston, Brad, Scheper, Rik J., Stewart, Clinton F., Schuetz, John D.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multidrug resistance-associated protein 4 is involved in the urinary excretion of hydrochlorothiazide and furosemide by HASEGAWA, Maki, KUSUHARA, Hiroyuki, ADACHI, Masashi, SCHUETZ, John D, TAKEUCHI, Kenji, SUGIYAMA, Yuichi

“…The role of ATP-binding cassette transporters in the urinary excretion of diuretics was investigated. Significant ATP-dependent uptake of hydrochlorothiazide…”
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Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis by MENNONE, Albert, SOROKA, Carol J, CAI, Shi-Ying, HARRY, Kathy, ADACHI, Masashi, HAGEY, Lee, SCHUETZ, John D, BOYER, James L

“…Mrp4 is a member of the multidrug resistance-associated gene family that is expressed on the basolateral membrane of hepatocytes and undergoes adaptive…”
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Involvement of MRP4 (ABCC4) in the luminal efflux of ceftizoxime and cefazolin in the kidney by Ci, Lei, Kusuhara, Hiroyuki, Adachi, Masashi, Schuetz, John D, Takeuchi, Kenji, Sugiyama, Yuichi

“…The purpose of the present study was to investigate the role of multidrug resistance-associated protein 4 (MRP4) in the tubular secretion of cephalosporin…”
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Partial silencing of fucosyltransferase 8 gene expression inhibits proliferation of Ishikawa cells, a cell line of endometrial cancer by Shimoyama, Hana, Shibata, Toshiaki K., Ito, Masahiko, Oda, Tomoaki, Itoh, Toshiya, Mukai, Mari, Matsuya-Ogawa, Madoka, Adachi, Masashi, Murakami, Hirotake, Nakayama, Takeshi, Sugihara, Kazuhiro, Itoh, Hiroaki, Suzuki, Tetsuro, Kanayama, Naohiro

“…Endometrial cancer is the most common gynecologic malignancy and is associated with increased morbidity each year, including young people. However, its…”
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Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice by Assem, Mahfoud, Schuetz, Erin G, Leggas, Markos, Sun, Daxi, Yasuda, Kazuto, Reid, Glen, Zelcer, Noam, Adachi, Masashi, Strom, Stephen, Evans, Ronald M, Moore, David D, Borst, Piet, Schuetz, John D

“…The ABC transporter, Mrp4, transports the sulfated steroid DHEA-s, and sulfated bile acids interact with Mrp4 with high affinity. Hepatic Mrp4 levels are low,…”
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Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities by Onodera, Yasuhito, Hashimoto, Shigeru, Hashimoto, Ari, Morishige, Masaki, Mazaki, Yuichi, Yamada, Atsuko, Ogawa, Eiji, Adachi, Masashi, Sakurai, Takaki, Manabe, Toshiaki, Wada, Hiromi, Matsuura, Nariaki, Sabe, Hisataka

“…Identification of the molecular machinery employed in cancer invasion, but not in normal adult cells, will greatly contribute to cancer therapeutics. Here we…”
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Essential roles of the Fas ligand in the development of hepatitis by Kondo, Toru, Suda, Takashi, Fukuyama, Hidehiro, Adachi, Masashi, Nagata, Shigekazu

“…The Fas ligand (FasL) is expressed in activated T cells and induces apoptosis in Fas-bearing cells. A cytotoxic T lymphocyte (CTL) clone specific for hepatitis…”
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Lethal effect of the anti-Fas antibody in mice by Ogasawara, Jun, Watanabe-Fukunaga, Rie, Adachi, Masashi, Matsuzawa, Akio, Kasugai, Tsutomu, Kitamura, Yukihiko, Itoh, Naoto, Suda, Takashi, Nagata, Shigekazu

“…During mammalian development, many cells are programmed to die most mediated by apoptosis. The Fas antigen coded by the structural gene for mouse…”
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Expression of MRP4 Confers Resistance to Ganciclovir and Compromises Bystander Cell Killing by Adachi, Masashi, Sampath, Janardhan, Lan, Lu-bin, Sun, Daxi, Hargrove, Philip, Flatley, Robin, Tatum, Ann, Edwards, Mary Z., Wezeman, Michele, Matherly, Larry, Drake, Richard, Schuetz, John

“…The multidrug resistance protein MRP4, a member of the ATP-binding cassette superfamily, confers resistance to purine-based antiretroviral agents. However, the…”
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Maspin expression and its clinical significance in non-small cell lung cancer by Nakagawa, Masatsugu, Katakura, Hiromichi, Adachi, Masashi, Takenaka, Kazumasa, Yanagihara, Kazuhiro, Otake, Yosuke, Wada, Hiromi, Tanaka, Fumihiro

“…Maspin is a member of the serpin (serine protease inhibitor) superfamily, and its exact function in the development and progression of malignant tumors remains…”
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Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12 by Tammur, Jaana, Prades, Catherine, Arnould, Isabelle, Rzhetsky, Andrey, Hutchinson, Amy, Adachi, Masashi, Schuetz, John D., Swoboda, Kathryn J., Ptácek, Louis J., Rosier, Marie, Dean, Michael, Allikmets, Rando

“…Several years ago, we initiated a long-term project of cloning new human ATP-binding cassette (ABC) transporters and linking them to various disease…”
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Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver by Adachi, Masashi, Suematsu, Sachiko, Kondo, Toru, Ogasawara, Jun, Tanaka, Takashi, Yoshida, Nobuaki, Nagata, Shigekazu

“…Fas, a type I membrane protein that transduces an apoptotic signal, is expressed in lymphocytes as well as in various tissues such as the liver, lung and…”
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Significance of Integrin α5 Gene Expression as a Prognostic Factor in Node-negative Non-Small Cell Lung Cancer by ADACHI, M, TAKI, T, HIGASHIYAMA, M, KOHNO, N, INUFUSA, H, MIYAKE, M

“…The integrin family plays a major role in complex biological events such as differentiation, development, wound healing, and the altered adhesive and invasive…”
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Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis by Inoue, K, Wen, R, Rehg, J E, Adachi, M, Cleveland, J L, Roussel, M F, Sherr, C J

“…The DMP1 transcription factor induces the ARF tumor suppressor gene in mouse fibroblasts, leading to cell cycle arrest in a p53-dependent manner. We disrupted…”
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Transmembrane 4 superfamily as a prognostic factor in pancreatic cancer by Sho, Masayuki, Adachi, Masashi, Taki, Toshihiko, Hashida, Hiroki, Konishi, Takaaki, Huang, Cheng‐long, Ikeda, Naoya, Nakajima, Yoshiyuki, Kanehiro, Hiromichi, Hisanaga, Michiyoshi, Nakano, Hiroshige, Miyake, Masayuki

“…Several members of the transmembrane 4 superfamily (TM4SF) have been reported to be related to tumor progression and metastasis. The aims of our study were to…”
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