Search Results - "ADACHI, Hideki"

A bispecific antibody to factors IXa and X restores factor VIII hemostatic activity in a hemophilia A model by Kitazawa, Takehisa, Igawa, Tomoyuki, Sampei, Zenjiro, Muto, Atsushi, Kojima, Tetsuo, Soeda, Tetsuhiro, Yoshihashi, Kazutaka, Okuyama-Nishida, Yukiko, Saito, Hiroyuki, Tsunoda, Hiroyuki, Suzuki, Tsukasa, Adachi, Hideki, Miyazaki, Taro, Ishii, Shinya, Kamata-Sakurai, Mika, Iida, Takeo, Harada, Aya, Esaki, Keiko, Funaki, Miho, Moriyama, Chifumi, Tanaka, Eriko, Kikuchi, Yasufumi, Wakabayashi, Tetsuya, Wada, Manabu, Goto, Masaaki, Toyoda, Takeshi, Ueyama, Atsunori, Suzuki, Sachiyo, Haraya, Kenta, Tachibana, Tatsuhiko, Kawabe, Yoshiki, Shima, Midori, Yoshioka, Akira, Hattori, Kunihiro

“…Individuals with hemophilia A lack the coagulation factor FVIII and are treated with frequent intravenous injections of FVIII agents. However, many individuals…”
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Cynomolgus monkey model of interleukin‐31‐induced scratching depicts blockade of human interleukin‐31 receptor A by a humanized monoclonal antibody by Oyama, Sohei, Kitamura, Hidetomo, Kuramochi, Taichi, Higuchi, Yoshinobu, Matsushita, Hiroaki, Suzuki, Tsukasa, Goto, Masaaki, Adachi, Hideki, Kasutani, Keiko, Sakamoto, Akihisa, Iwayanagi, Yuki, Kaneko, Akihisa, Nanami, Masahiko, Fujii, Etsuko, Esaki, Keiko, Takashima, Yoshiaki, Shimaoka, Shin, Hattori, Kunihiro, Kawabe, Yoshiki

“…Scratching is an important factor exacerbating skin lesions through the so‐called itch‐scratch cycle in atopic dermatitis (AD). In mice, interleukin (IL)‐31…”
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FEEL-1, a Novel Scavenger Receptor with in Vitro Bacteria-binding and Angiogenesis-modulating Activities by Adachi, Hideki, Tsujimoto, Masafumi

“…Employing the expression cloning technique, we cloned a novel scavenger receptor that is structurally unrelated to other scavenger receptors. The cloned…”
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Role of Scavenger Receptors in the Binding and Internalization of Heat Shock Protein 70 by Theriault, Jimmy R, Adachi, Hideki, Calderwood, Stuart K

“…Extracellular heat shock protein 70 (Hsp70) exerts profound effects both in mediating tumor rejection by Hsp70-based vaccines and in autoimmunity. Further…”
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The PIGRET assay, a method for measuring Pig-a gene mutation in reticulocytes, is reliable as a short-term in vivo genotoxicity test: Summary of the MMS/JEMS-collaborative study across 16 laboratories using 24 chemicals by Kimoto, Takafumi, Horibata, Katsuyoshi, Miura, Daishiro, Chikura, Satsuki, Okada, Yuki, Ukai, Akiko, Itoh, Satoru, Nakayama, Shiho, Sanada, Hisakazu, Koyama, Naomi, Muto, Shigeharu, Uno, Yoshifumi, Yamamoto, Mika, Suzuki, Yuta, Fukuda, Takayuki, Goto, Ken, Wada, Kunio, Kyoya, Takahiro, Shigano, Miyuki, Takasawa, Hironao, Hamada, Shuichi, Adachi, Hideki, Uematsu, Yasuaki, Tsutsumi, Eri, Hori, Hisako, Kikuzuki, Ryuta, Ogiwara, Yosuke, Yoshida, Ikuma, Maeda, Akihisa, Narumi, Kazunori, Fujiishi, Yohei, Morita, Takeshi, Yamada, Masami, Honma, Masamitsu

“…•The PIGRET assay offers strong potential as a short-term in vivo genotoxicity test.•Technical transferability of both the PIGRET and RBC Pig-a assay was…”
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Self-organization, quality control, and preclinical studies of human iPSC-derived retinal sheets for tissue-transplantation therapy by Watari, Kenji, Yamasaki, Suguru, Tu, Hung-Ya, Shikamura, Masayuki, Kamei, Tatsuya, Adachi, Hideki, Tochitani, Tomoaki, Kita, Yasuyuki, Nakamura, Aya, Ueyama, Kazuki, Ono, Keiichi, Morinaga, Chikako, Matsuyama, Take, Sho, Junki, Nakamura, Miyuki, Fujiwara, Masayo, Hori, Yoriko, Tanabe, Anna, Hirai, Rina, Terai, Orie, Ohno, Osamu, Ohara, Hidetaka, Hayama, Tetsuya, Ikeda, Atsushi, Nukaya, Daiki, Matsushita, Keizo, Takahashi, Masayo, Kishino, Akiyoshi, Kimura, Toru, Kawamata, Shin, Mandai, Michiko, Kuwahara, Atsushi

“…Three-dimensional retinal organoids (3D-retinas) are a promising graft source for transplantation therapy. We previously developed self-organizing culture for…”
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The discrepancy between serum creatinine and cystatin C can predict renal function after treatment for postrenal acute kidney injury: multicenter study and pooled data analysis by Matsuki, Masahiro, Tanaka, Toshiaki, Maehana, Takeshi, Kyoda, Yuki, Ichihara, Koji, Hashimoto, Kohei, Yanase, Masahiro, Matsukawa, Masanori, Adachi, Hideki, Takahashi, Satoshi, Masumori, Naoya

“…Background Although serum cystatin C and creatinine are used as practical markers of renal function, the discrepancy between them in postrenal acute kidney…”
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N-glycans of SREC-I (scavenger receptor expressed by endothelial cells): essential role for ligand binding, trafficking and stability by Sano, Masahiro, Korekane, Hiroaki, Ohtsubo, Kazuaki, Yamaguchi, Yoshiki, Kato, Masaki, Shibukawa, Yukinao, Tajiri, Michiko, Adachi, Hideki, Wada, Yoshinao, Asahi, Michio, Taniguchi, Naoyuki

“…Scavenger receptor expressed by endothelial cells (SREC-I) mediates the endocytosis of chemically modified lipoproteins such as acetylated low-density…”
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FEEL-1 and FEEL-2 Are Endocytic Receptors for Advanced Glycation End Products by Tamura, Yoshiaki, Adachi, Hideki, Osuga, Jun-ichi, Ohashi, Ken, Yahagi, Naoya, Sekiya, Motohiro, Okazaki, Hiroaki, Tomita, Sachiko, Iizuka, Yoko, Shimano, Hitoshi, Nagai, Ryozo, Kimura, Satoshi, Tsujimoto, Masafumi, Ishibashi, Shun

“…Advanced glycation end products (AGEs) are nonenzymatically glycosylated proteins, which accumulate in vascular tissues in aging and diabetes. Receptors for…”
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Effect of Microscopic Internal Structure on Sound Absorption Properties of Polyurethane Foam by X-ray Computed Tomography Observations by Yamashita, Tsuyoshi, Suzuki, Kazuhiro, Adachi, Hideki, Nishino, Souichiro, Tomota, Yo

“…We investigated several conditions for manufacturing polyurethane foam for motor vehicle application to clarify the effect of the material structure on sound…”
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Fever after Gemcitabine Administration is a Poor Prognostic Factor in Patients with Metastatic Urothelial Carcinoma : Multicenter Retrospective Study by Maehana, Takeshi, Tanaka, Toshiaki, Shindo, Tetsuya, Takahashi, Atushi, Ito, Naoki, Taguchi, Keisuke, Hotta, Hiroshi, Tachiki, Hitoshi, Matsukawa, Masanori, Adachi, Hideki, Kato, Ryuichi, Kunishima, Yasuharu, Masumori, Naoya

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Efficacy and safety of docetaxel and prednisolone for castration-resistant prostate cancer: a multi-institutional retrospective study in Japan by Fukuta, Fumimasa, Kitamura, Hiroshi, Yanase, Masahiro, Taguchi, Keisuke, Takahashi, Atsushi, Kunishima, Yasuharu, Miyake, Masafumi, Adachi, Hideki, Itoh, Naoki, Hirose, Takaoki, Takagi, Seiji, Miyao, Noriomi, Matsukawa, Masanori, Shigyo, Masanori, Masumori, Naoya

“…Although some new drugs for castration-resistant prostate cancer are available, docetaxel still plays an important role in castration-resistant prostate cancer…”
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Expression Cloning of a Novel Scavenger Receptor from Human Endothelial Cells by Adachi, Hideki, Tsujimoto, Masafumi, Arai, Hiroyuki, Inoue, Keizo

“…Scavenger receptors mediate the endocytosis of chemically modified lipoproteins, such as acetylated low density lipoprotein (Ac-LDL) and oxidized LDL (Ox-LDL),…”
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Identification of a PDZ-Domain-Containing Protein That Interacts with the Scavenger Receptor Class B Type I by Ikemoto, Mamoru, Arai, Hiroyuki, Feng, Dongdong, Tanaka, Kazumi, Aoki, Junken, Dohmae, Naoshi, Takio, Koji, Adachi, Hideki, Tsujimoto, Masafumi, Inoue, Keizo

“…The scavenger receptor class B type I (SR-BI) mediates the selective uptake of cholesteryl esters from high-density lipoprotein (HDL) and cholesterol secretion…”
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SREC-II, a New Member of the Scavenger Receptor Type F Family, Trans-interacts with SREC-I through Its Extracellular Domain by Ishii, Junko, Adachi, Hideki, Aoki, Junken, Koizumi, Hiroyuki, Tomita, Susumu, Suzuki, Toshiharu, Tsujimoto, Masafumi, Inoue, Keizo, Arai, Hiroyuki

“…The scavenger receptor expressed by endothelial cells (SREC) with an extremely large cytoplasmic domain, was originally identified in a human endothelial cell…”
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Characterization of the Human Gene Encoding the Scavenger Receptor Expressed by Endothelial Cell and Its Regulation by a Novel Transcription Factor, Endothelial Zinc Finger Protein-2 by Adachi, Hideki, Tsujimoto, Masafumi

“…The scavenger receptor expressed by endothelial cell (SREC), mediates the selective uptake of modified low density lipoprotein (LDL), such as acetylated LDL…”
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Modification of an abdominal diagnosis teaching simulator to reproduce patterns of resistance to pressure by Yakubo, Shuji, Ueda, Yukiko, Muroga, Kazuhiro, Tanekura, Naomichi, Okudaira, Tomoyuki, Sasanuma, Toshifumi, Adachi, Hideki, Ishino, Shogo, Nakayama, Takashi, Yamanaka, Kazufumi, Namiki, Takao

“…ABSTRACT Aim Within the Kampo medical system, there exists a system specific to Japan of abdominal diagnosis called abdominal palpation, or Fukushin, which is…”
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Serum cystatin C can be used as a marker of renal function even in patients with intestinal urinary diversion by Matsuki, Masahiro, Tanaka, Toshiaki, Maehana, Takeshi, Ichihara, Koji, Yanase, Masahiro, Matsukawa, Masanori, Adachi, Hideki, Takahashi, Satoshi, Masumori, Naoya

“…Objective: Recently, serum cystatin C (CysC) has been used as a novel marker of renal function. However, there is a lack of data on CysC levels in patients…”
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Scavenger Receptor Expressed by Endothelial Cells I (SREC-I) Mediates the Uptake of Acetylated Low Density Lipoproteins by Macrophages Stimulated with Lipopolysaccharide by Tamura, Yoshiaki, Osuga, Jun-ichi, Adachi, Hideki, Tozawa, Ryu-ichi, Takanezawa, Yasukazu, Ohashi, Ken, Yahagi, Naoya, Sekiya, Motohiro, Okazaki, Hiroaki, Tomita, Sachiko, Iizuka, Yoko, Koizumi, Hiroyuki, Inaba, Toshihiro, Yagyu, Hiroaki, Kamada, Nobuo, Suzuki, Hiroshi, Shimano, Hitoshi, Kadowaki, Takashi, Tsujimoto, Masafumi, Arai, Hiroyuki, Yamada, Nobuhiro, Ishibashi, Shun

“…Scavenger receptor expressed by endothelial cells I (SREC-I) is a novel endocytic receptor for acetylated low density lipoprotein (LDL). Here we show that…”
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Type F Scavenger Receptor SREC-I Interacts with Advillin, a Member of the Gelsolin/Villin Family, and Induces Neurite-like Outgrowth by Shibata, Mami, Ishii, Junko, Koizumi, Hiroyuki, Shibata, Norihito, Dohmae, Naoshi, Takio, Koji, Adachi, Hideki, Tsujimoto, Masafumi, Arai, Hiroyuki

“…The scavenger receptor expressed by endothelial cells (SREC) was isolated from a human endothelial cell line and consists of two isoforms named SREC-I and -II…”
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