Search Results - "ACTON, R. T"

Influence of CYP2C9 and VKORC1 1173C/T Genotype on the Risk of Hemorrhagic Complications in African‐American and European‐American Patients on Warfarin by Limdi, NA, McGwin, G, Goldstein, JA, Beasley, TM, Arnett, DK, Adler, BK, Baird, MF, Acton, RT

“…The association of CYP2C9 and VKORC1 1173C/T genotype and risk of hemorrhage among African Americans and European Americans is presented. This association was…”
Get full text

Influence of CYP2C9 and VKORC1 on warfarin response during initiation of therapy by Limdi, N.A., Wiener, H., Goldstein, J.A., Acton, R.T., Beasley, T.M.

“…Although multiple reports have documented the influence of CYP2C9 and VKORC1 variants on warfarin dose, risk of over-anticoagulation and hemorrhage, their…”
Get full text

DMPK-associated myotonic dystrophy and CTG repeats in Alabama African Americans by Acton, RT, Rivers, CA, Watson, B, Oh, SJ

“…Myotonic dystrophy type 1 (DM1) is a result of a CTG expansion in the 3′‐untranslated region of the DMPK gene. DM1 is rare among African blacks who have fewer…”
Get full text

A genome-wide linkage scan for iron phenotype quantitative trait loci: the HEIRS Family Study by Acton, RT, Snively, BM, Barton, JC, McLaren, CE, Adams, PC, Rich, SS, Eckfeldt, JH, Press, RD, Sholinsky, P, Leiendecker-Foster, C, McLaren, GD, Speechley, MR, Harris, EL, Dawkins, FW, Gordeuk, VR

“…Iron overload phenotypes in persons with and without hemochromatosis are variable. To investigate this further, probands with hemochromatosis or evidence of…”
Get full text

Racial differences in the prevalence of Factor V Leiden mutation among patients on chronic warfarin therapy by Limdi, N.A., Beasley, T.M., Allison, D.B., Rivers, C.A., Acton, R.T.

“…We report the prevalence of Factor V Leiden (FVL) in European American and African American patients on warfarin therapy residing in Alabama. Detailed history…”
Get full text

Plasma homocyst(e)ine, folate, and vitamin B-12 concentrations and risk for early-onset coronary artery disease by Pancharuniti, N, Lewis, CA, Sauberlich, HE, Perkins, LL, Go, RC, Alvarez, JO, Macaluso, M, Acton, RT, Copeland, RB, Cousins, AL, Gore, TB, Cornwell, PE, Roseman, JM

“…High plasma homocyst(e)ine (Hcy) concentrations may be a determinant of coronary artery disease (CAD). Folate and vitamin B-12 are required for the primary…”
Get full text

Vibrio vulnificus Infection in a Hemodialysis Patient Receiving Intravenous Iron Therapy by Barton, James C., Coghlan, Michael E., Reymann, Michael T., Ozbirn, Thomas W., Acton, Ronald T.

“…A 73-year-old man treated with long-term hemodialysis, erythropoietin, and intravenous iron sucrose infusions developed Vibrio vulnificus infection after…”
Get full text

Fibromyalgia in 300 adult index patients with primary immunodeficiency by Barton, James C, Bertoli, Luigi F, Barton, Jackson C, Acton, Ronald T

“…We sought to determine the prevalence and clinical and laboratory associations of fibromyalgia in adults with primary immunodeficiency (immunoglobulin (Ig) G…”
Get full text

Genetic association of 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2) flanking microsatellites with essential hypertension in blacks by WATSON, B. JR, BERGMAN, S. M, MYRACLE, A, CALLEN, D. F, ACTON, R. T, WARNOCK, D. G

“…11 beta-Hydroxysteroid dehydrogenase type 2 (11 beta-HSD2) specifically modulates access of the mineralocorticoid aldosterone to the kidney mineralocorticoid…”
Get full text

Variability of the pancreatic islet beta cell/liver (GLUT 2) glucose transporter gene in NIDDM patients by TANIZAWA, Y, RIGGS, A. C, CHIU, K. C, JANSSEN, R. C, BELL, D. S. H, GO, R. P. C, ROSEMAN, J. M, ACTON, R. T, PERMUTT, M. A

“…The purpose of these experiments was to test the hypothesis that impaired glucose-stimulated insulin secretion in NIDDM is due to mutations in the islet beta…”
Get full text

Glucokinase gene in gestational diabetes mellitus : population association study and molecular scanning by CHIU, K. C, GO, R. C. P, AOKI, M, RIGGS, A. C, TANIZAWA, Y, ACTON, R. T, BELL, D. S. H, GOLDENBERG, R. L, ROSEMAN, J. M, PERMUTT, M. A

“…Mutations of the glucokinase gene result in early-onset familial Type 2 (non-insulin-dependent) diabetes mellitus, and several members of the mutant…”
Get full text

Toxicity of methotrexate in rheumatoid arthritis by Gispen, J G, Alarcón, G S, Johnson, J J, Acton, R T, Barger, B O, Koopman, W J

“…Seventy-two patients with rheumatoid arthritis had been treated with pulse weekly oral methotrexate with a mean followup of one year. Minor side effects (oral…”
Get more information

Associations of MHC genes with levels of caries-inducing organisms and caries severity in African-American women by Acton, Ronald T, Dasanayake, Ananda P, Harrison, Renee A, Li, Yihong, Roseman, Jeffrey M, Go, Rodney C.P, Wiener, Howard, Caufield, Page W

“…The aim of this investigation was to evaluate the relationship between MHC alleles at the HLA-DRB1, DQB1 and TNFa microsatellite loci and levels of oral…”
Get full text

Restriction fragment length polymorphism analysis of HLA-DR, DQ, DP and C4 alleles in Caucasians with systemic lupus erythematosus by Reveille, J D, Anderson, K L, Schrohenloher, R E, Acton, R T, Barger, B O

“…HLA-DR, DQ, DP and C4 null alleles were determined by restriction fragment length polymorphism (RFLP) analysis in 60 Caucasian patients with systemic lupus…”
Get more information

Relationships of serum free thyroxine and erythrocyte measures in euthyroid HFE C282Y homozygotes and control subjects: the HEIRS Study by BARTON, J. C., LEIENDECKER-FOSTER, C., REBOUSSIN, D. M., ADAMS, P. C., ACTON, R. T., ECKFELDT, J. H.

“…Summary Hemoglobin (Hb) levels and mean corpuscular volume (MCV) are abnormal in some persons with hemochromatosis or thyroid disorders. We sought to determine…”
Get full text

Genes within and flanking the major histocompatibility region are risk factors for diabetes, insulin resistance, hypertension, and microalbuminuria in African-American women by Acton, R.T., Bell, D.S.H., Collins, J., Giger, J.N., Go, R.C.P., Harrison, R., McDonald, R., Rivers, C., Roseman, J.M., Taylor, H.A., Vanichanan, C.

Get full text

Increased prevalence of mitral valve prolapse in IDDM by Bell, D S, Acton, R T

Get full text

SSCP analysis and sequencing of the human prion protein gene (PRNP) detects two different 24 bp deletions in an atypical Alzheimer's disease family by Perry, R T, Go, R C, Harrell, L E, Acton, R T

“…Alzheimer's disease (AD) is a progressive, degenerative neurological disorder of the central nervous system. AD is the fourth leading cause of death in elderly…”
Get more information

Knowledge, attitudes, and behaviors of Alabama's primary care physicians regarding cancer genetics by Acton, R T, Burst, N M, Casebeer, L, Ferguson, S M, Greene, P, Laird, B L, Leviton, L

“…To determine Alabama's primary care physicians' knowledge, attitudes, and behaviors regarding cancer genetics. A questionnaire was mailed to a random sample of…”
Get full text

Concordance of 21-hydroxylase gene ratio, human leukocyte antigen haplotyping and adrenal testing results in a family with late-onset adrenal hyperplasia by WELLS, G, ACTON, R. T, AZZIZ, R

“…Late-onset adrenal hyperplasia (LOAH) due to 21-hydroxylase (21-OH) deficiency is one of the most common autosomal recessive disorders. There appear to be two…”
Get full text