Search Results - "ACOSTA, DANIEL"
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Machine learning-aided engineering of hydrolases for PET depolymerization
Published in Nature (London) (28-04-2022)“…Plastic waste poses an ecological challenge 1 – 3 and enzymatic degradation offers one, potentially green and scalable, route for polyesters waste recycling 4…”
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2
PrimPol‐mediated repriming facilitates replication traverse of DNA interstrand crosslinks
Published in The EMBO journal (15-07-2021)“…DNA interstrand crosslinks (ICLs) induced by endogenous aldehydes or chemotherapeutic agents interfere with essential processes such as replication and…”
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3
DNA replication and replication stress response in the context of nuclear architecture
Published in Chromosoma (2024)“…The DNA replication process needs to be coordinated with other DNA metabolism transactions and must eventually extend to the full genome, regardless of…”
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4
Advances in enzymatic and organismal technologies for the recycling and upcycling of petroleum-derived plastic waste
Published in Current opinion in biotechnology (01-12-2023)“…Biological catalysts are emerging with the capability to depolymerize a wide variety of plastics. Improving and discovering these catalysts has leveraged a…”
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5
PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells
Published in Molecular cell (06-02-2020)“…Acute treatment with replication-stalling chemotherapeutics causes reversal of replication forks. BRCA proteins protect reversed forks from nucleolytic…”
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6
PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts
Published in Nature communications (17-11-2020)“…Stalled replication forks can be restarted and repaired by RAD51-mediated homologous recombination (HR), but HR can also perform post-replicative repair after…”
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7
Management of persistent air leak in Neonates: A case series
Published in Journal of neonatal surgery (28-05-2023)“…Background: Autologous blood patch pleurodesis (ABPP) has been used in adults as an efficient and safe technique to address persistent air leak (PAL). A fibrin…”
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8
RAD51 restricts DNA over-replication from re-activated origins
Published in The EMBO journal (15-03-2024)“…Eukaryotic cells rely on several mechanisms to ensure that the genome is duplicated precisely once in each cell division cycle, preventing DNA over-replication…”
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9
Predicting the thermal regime of the Po Plain subsurface (Italy) using geostatistical modeling constrained by legacy wells
Published in Marine and petroleum geology (01-09-2024)“…Italy boasts a long history of hydrocarbon exploration. The Po Basin, in particular, has been extensively explored due to its peculiar geological setting,…”
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10
Low Cost Magnetic Field Control for Disabled People
Published in Sensors (Basel, Switzerland) (16-01-2023)“…Our research presents a cost-effective navigation system for electric wheelchairs that utilizes the tongue as a human-machine interface (HMI) for disabled…”
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11
Improving Odometric Model Performance Based on LSTM Networks
Published in Sensors (Basel, Switzerland) (14-01-2023)“…This paper presents a localization system for an autonomous wheelchair that includes several sensors, such as odometers, LIDARs, and an IMU. It focuses on…”
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12
Nuclear actin polymerization rapidly mediates replication fork remodeling upon stress by limiting PrimPol activity
Published in Nature communications (28-11-2023)“…Cells rapidly respond to replication stress actively slowing fork progression and inducing fork reversal. How replication fork plasticity is achieved in the…”
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13
Improving Mobile Robot Maneuver Performance Using Fractional-Order Controller
Published in Sensors (Basel, Switzerland) (16-03-2023)“…In this paper, the low-level velocity controller of an autonomous vehicle is studied. The performance of the traditional controller used in this kind of…”
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14
Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme
Published in Nature communications (07-03-2024)“…A major challenge to achieving industry-scale biomanufacturing of therapeutic alkaloids is the slow process of biocatalyst engineering. Amaryllidaceae…”
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15
Magnetosensitivity in the Stingless Bee Tetragonisca angustula: Magnetic Inclination Can Alter the Choice of the Flying Departure Angle From the Nest
Published in Bioelectromagnetics (01-01-2021)“…It is known that animals are sensitive to the geomagnetic field. In the case of insects, magnetoreception has been reported in several ant species and in some…”
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Toxicity Testing in the 21st Century: A Vision and a Strategy
Published in Journal of toxicology and environmental health. Part B, Critical reviews (01-02-2010)“…With the release of the landmark report Toxicity Testing in the 21st Century: A Vision and a Strategy, the U.S. National Academy of Sciences, in 2007,…”
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Psychosocial health of school-aged children during the initial COVID-19 safer-at-home school mandates in Florida: a cross-sectional study
Published in BMC public health (29-03-2021)“…Given the emerging literature regarding the impacts of lockdown measures on mental health, this study aims to describe the psychosocial health of school-aged…”
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18
Functional interplay between c‐Myc and Max in B lymphocyte differentiation
Published in EMBO reports (01-10-2018)“…The Myc family of oncogenic transcription factors regulates myriad cellular functions. Myc proteins contain a basic region/helix‐loop‐helix/leucine zipper…”
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Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming
Published in Molecular cell (03-11-2022)“…Stem cell division is linked to tumorigenesis by yet-elusive mechanisms. The hematopoietic system reacts to stress by triggering hematopoietic stem and…”
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Magnetosome magnetite biomineralization in a flagellated protist: evidence for an early evolutionary origin for magnetoreception in eukaryotes
Published in Environmental microbiology (01-04-2020)“…Summary The most well‐recognized magnetoreception behaviour is that of the magnetotactic bacteria (MTB), which synthesize membrane‐bounded magnetic…”
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