Search Results - "ACKERMANN, Uwe"

Microalgae wastewater treatment: Biological and technological approaches by Wollmann, Felix, Dietze, Stefan, Ackermann, Jörg‐Uwe, Bley, Thomas, Walther, Thomas, Steingroewer, Juliane, Krujatz, Felix

“…Current global environmental issues raise unavoidable challenges for our use of natural resources. Supplying the human population with clean water is becoming…”
Get full text

Removal of sugars in wastewater from food production through heterotrophic growth of Galdieria sulphuraria by Scherhag, Philipp, Ackermann, Jörg‐Uwe

“…The unicellular extremophilic red alga Galdieria sulphuraria is capable of chemoheterotrophy and its growth has been investigated on some defined and undefined…”
Get full text

18F Site-Specific Labelling of a Single-Chain Antibody against Activated Platelets for the Detection of Acute Thrombosis in Positron Emission Tomography by Ardipradja, Katie S., Wichmann, Christian W., Hickson, Kevin, Rigopoulos, Angela, Alt, Karen M., Pearce, Hannah A., Wang, Xiaowei, O’Keefe, Graeme, Scott, Andrew M., Peter, Karlheinz, Hagemeyer, Christoph E., Ackermann, Uwe

“…Positron emission tomography is the imaging modality of choice when it comes to the high sensitivity detection of key markers of thrombosis and inflammation,…”
Get full text

Radiolabelling and preclinical characterization of 89Zr-Df-radiolabelled bispecific anti-PD-L1/TGF-βRII fusion protein bintrafusp alfa by Burvenich, Ingrid Julienne Georgette, Goh, Yit Wooi, Guo, Nancy, Gan, Hui Kong, Rigopoulos, Angela, Cao, Diana, Liu, Zhanqi, Ackermann, Uwe, Wichmann, Christian Werner, McDonald, Alexander Franklin, Huynh, Nhi, O’Keefe, Graeme Joseph, Gong, Sylvia Jie, Scott, Fiona Elizabeth, Li, Linghui, Geng, Wanping, Zutshi, Anup, Lan, Yan, Scott, Andrew Mark

“…Purpose Τhis study aimed to optimize the 89 Zr-radiolabelling of bintrafusp alfa investigational drug product and controls, and perform the in vitro and in…”
Get full text

Human biodistribution and internal dosimetry of 4-[ 18F]fluorobenzyl-dexetimide: a PET radiopharmaceutical for imaging muscarinic acetylcholine receptors in the brain and heart by Pain, Cameron D., O’Keefe, Graeme J., Ackermann, Uwe, Dore, Vincent, Villemagne, Victor L., Rowe, Christopher C.

“…Background 4-[ 18 F] fluorobenzyl dexetimide (F-DEX) is the first non-subtype selective fluorine-18 labelled tracer for muscarinic receptors (mAChR) used in…”
Get full text

Automated synthesis of 18F radiolabelled indole containing Oncrasin-like molecules; a comparison of iodonium salts and boronic ester chemistry by McDonald, Alexander F., Goh, Yit Wooi, White, Jonathan M., Scott, Andrew M., Ackermann, Uwe

“…Background Oncrasin-1 is a small molecule which was identified from a screen of KRAS mutant cancer cells and has shown specificity for KRAS mutant cell…”
Get full text

Synthesis and validation of [18F]mBPET-1, a fluorine-18 labelled mTOR inhibitor derivative based on a benzofuran backbone by Wichmann, Christian W., Goh, Yit Wooi, Parslow, Adam C., Rigopoulos, Angela, Guo, Nancy, Scott, Andrew M., Ackermann, Uwe, White, Jonathan M.

“…Background Targeted therapy of HER2 positive breast cancer has led to clinical success in some cases with primary and secondary resistance being major…”
Get full text

Complexation of Europium(III) with the Zwitterionic Form of Amino Acids Studied with Ultraviolet—Visible and Time-Resolved Laser-Induced Fluorescence Spectroscopy by Heller, Anne, Rönitz, Olivia, Barkleit, Astrid, Bernhard, Gert, Ackermann, Jörg-Uwe

“…The complex formation of europium(III) with the zwitterionic form of amino acids (alanine, phenylalanine, and threonine) has been studied in aqueous solution…”
Get full text

Complexation study of europium(III) and curium(III) with urea in aqueous solution investigated by time-resolved laser-induced fluorescence spectroscopy by Heller, Anne, Barkleit, Astrid, Bernhard, Gert, Ackermann, Jörg-Uwe

“…The complex formation of europium(III) and curium(III) with urea has been studied using TRLFS. Stability constants were determined to be log β 110 = −0.12 ±…”
Get full text

l-Tyrosine Confers Residualizing Properties to a d-Amino Acid-Rich Residualizing Peptide for Radioiodination of Internalizing Antibodies by Lee, Fook T., Burvenich, Ingrid J. G., Guo, Nancy, Kocovski, Pece, Tochon-Danguy, Henri, Ackermann, Uwe, O’Keefe, Graeme J., Gong, Sylvia, Rigopoulos, Angela, Liu, Zhanqi, Gan, Hui K., Scott, Andrew M.

“…Purpose: The aims of the study were to develop and evaluate a novel residualizing peptide for labeling internalizing antibodies with 124I to support clinical…”
Get full text

On-line monitoring of lipid storage in yeasts using impedance spectroscopy by Maskow, Thomas, Röllich, Anita, Fetzer, Ingo, Ackermann, Jörg-Uwe, Harms, Hauke

“…Bioremediation technologies and many environmentally sound biosyntheses rely on the catalytic potential of whole cells. For analyzing and controlling such…”
Get full text

A simplified protocol for the automated production of succinimidyl 4-[18F]fluorobenzoate on an IBA Synthera module by Ackermann, Uwe, Yeoh, Shinn Dee, Sachinidis, John I., Poniger, Stan S., Scott, Andrew M., Tochon-Danguy, Henri J.

“…The important peptide labelling reagent succinimidyl 4‐[18F]fluorobenzoate ([18F]SFB) has been synthesised in 75–85% decay corrected radiochemical yield using…”
Get full text

Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease by Villemagne, Victor L., Pike, Kerryn E., Chételat, Gaël, Ellis, Kathryn A., Mulligan, Rachel S., Bourgeat, Pierrick, Ackermann, Uwe, Jones, Gareth, Szoeke, Cassandra, Salvado, Olivier, Martins, Ralph, O'Keefe, Graeme, Mathis, Chester A., Klunk, William E., Ames, David, Masters, Colin L., Rowe, Christopher C.

“…Objective Assess Aβ deposition longitudinally and explore its relationship with cognition and disease progression. Methods Clinical follow‐up was obtained 20 ±…”
Get full text

Approaches to increase the economy of the PHB production by Ackermann, Jörg-Uwe, Babel, Wolfgang

“…The ability to synthesize PHB is widespread in prokaryotes. It is independent of the carbon source and the type of nutrition. PHB has several interesting…”
Get full text

18F-labeling and initial in vivo evaluation of a Hitomi peptide for imaging tissue transglutaminase 2 by Ackermann, Uwe, Jäger, Luise, Rigopoulos, Angela, Burvenich, Ingrid Julienne Georgette, O'Keefe, Graeme Joseph, Scott, Andrew M.

“…Tissue transglutaminase 2 (TG2) is a calcium-dependent enzyme which cross-links proteins. It is overexpressed in many diseases and plays a key role in tissue…”
Get full text

Imaging of neuroinflammation in adult Niemann-Pick type C disease: A cross-sectional study by Walterfang, Mark, Di Biase, Maria A., Cropley, Vanessa L., Scott, Andrew M., O'Keefe, Graeme, Velakoulis, Dennis, Pathmaraj, Kunthi, Ackermann, Uwe, Pantelis, Christos

“…OBJECTIVETo test the hypothesis that neuroinflammation is a key process in adult Niemann-Pick type C (NPC) disease, we undertook PET scanning utilizing a…”
Get full text

Abstract 2151: Development of small-molecule mTORC1 radiotracers for evaluation of targeted therapy resistance using PET by Parslow, Adam C., Wichmann, Christian W., Rigopoulos, Angela, Ackermann, Uwe, White, Jonathan M., Scott, Andrew M.

“…Overcoming resistance is an area of unmet clinical need for patients undergoing trastuzumab-based HER2-directed therapy. PTEN loss or PI3K mutation has been…”
Get full text

Automated radiosynthesis of [68Ga]Ga‐PSMA‐11 and [177Lu]Lu‐PSMA‐617 on the iPHASE MultiSyn module for clinical applications by Wichmann, Christian W., Ackermann, Uwe, Poniger, Stan, Young, Kenneth, Nguyen, Benjamin, Chan, Gordon, Sachinidis, John, Scott, Andrew M.

“…Prostate‐specific membrane antigen (PSMA)‐targeted imaging and therapy of prostate cancer using theranostic pairs is rapidly changing clinical practice. To…”
Get full text

Rhenium and Technetium-oxo Complexes with Thioamide Derivatives of Pyridylhydrazine Bifunctional Chelators Conjugated to the Tumour Targeting Peptides Octreotate and Cyclic-RGDfK by North, Andrea J, Karas, John A, Ma, Michelle T, Blower, Philip J, Ackermann, Uwe, White, Jonathan M, Donnelly, Paul S

“…This research aimed to develop new tumor targeted theranostic agents taking advantage of the similarities in coordination chemistry between technetium and…”
Get full text

18 F-labeling and initial in vivo evaluation of a Hitomi peptide for imaging tissue transglutaminase 2 by Ackermann, Uwe, Jäger, Luise, Rigopoulos, Angela, Burvenich, Ingrid Julienne Georgette, O'Keefe, Graeme Joseph, Scott, Andrew M

“…Tissue transglutaminase 2 (TG2) is a calcium-dependent enzyme which cross-links proteins. It is overexpressed in many diseases and plays a key role in tissue…”
Get full text