Search Results - "ACKER, Till"

Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction by Tombor, Lukas S., John, David, Glaser, Simone F., Luxán, Guillermo, Forte, Elvira, Furtado, Milena, Rosenthal, Nadia, Baumgarten, Nina, Schulz, Marcel H., Wittig, Janina, Rogg, Eva-Maria, Manavski, Yosif, Fischer, Ariane, Muhly-Reinholz, Marion, Klee, Kathrin, Looso, Mario, Selignow, Carmen, Acker, Till, Bibli, Sofia-Iris, Fleming, Ingrid, Patrick, Ralph, Harvey, Richard P., Abplanalp, Wesley T., Dimmeler, Stefanie

“…Endothelial cells play a critical role in the adaptation of tissues to injury. Tissue ischemia induced by infarction leads to profound changes in endothelial…”
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Endothelial Dab1 signaling orchestrates neuro-glia-vessel communication in the central nervous system by Segarra, Marta, Aburto, Maria R, Cop, Florian, Llaó-Cid, Cecília, Härtl, Ricarda, Damm, Miriam, Bethani, Ioanna, Parrilla, Marta, Husainie, Dewi, Schänzer, Anne, Schlierbach, Hannah, Acker, Till, Mohr, Laura, Torres-Masjoan, Laia, Ritter, Mathias, Acker-Palmer, Amparo

“…The architecture of the neurovascular unit (NVU) is controlled by the communication of neurons, glia, and vascular cells. We found that the neuronal guidance…”
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Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body by Pan, Chenchen, Schoppe, Oliver, Parra-Damas, Arnaldo, Cai, Ruiyao, Todorov, Mihail Ivilinov, Gondi, Gabor, von Neubeck, Bettina, Böğürcü-Seidel, Nuray, Seidel, Sascha, Sleiman, Katia, Veltkamp, Christian, Förstera, Benjamin, Mai, Hongcheng, Rong, Zhouyi, Trompak, Omelyan, Ghasemigharagoz, Alireza, Reimer, Madita Alice, Cuesta, Angel M., Coronel, Javier, Jeremias, Irmela, Saur, Dieter, Acker-Palmer, Amparo, Acker, Till, Garvalov, Boyan K., Menze, Bjoern, Zeidler, Reinhard, Ertürk, Ali

“…Reliable detection of disseminated tumor cells and of the biodistribution of tumor-targeting therapeutic antibodies within the entire body has long been needed…”
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Infratentorial IDH-mutant astrocytoma is a distinct subtype by Banan, Rouzbeh, Stichel, Damian, Bleck, Anja, Hong, Bujung, Lehmann, Ulrich, Suwala, Abigail, Reinhardt, Annekathrin, Schrimpf, Daniel, Buslei, Rolf, Stadelmann, Christine, Ehlert, Karoline, Prinz, Marco, Acker, Till, Schittenhelm, Jens, Kaul, David, Schweizer, Leonille, Capper, David, Harter, Patrick N., Etminan, Nima, Jones, David T. W., Pfister, Stefan M., Herold-Mende, Christel, Wick, Wolfgang, Sahm, Felix, von Deimling, Andreas, Hartmann, Christian, Reuss, David E.

“…Diffuse IDH-mutant astrocytic tumors are rarely diagnosed in the cerebellum or brainstem. In this multi-institutional study, we characterized a series of…”
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Acidosis Acts through HSP90 in a PHD/VHL-Independent Manner to Promote HIF Function and Stem Cell Maintenance in Glioma by Filatova, Alina, Seidel, Sascha, Böğürcü, Nuray, Gräf, Sabine, Garvalov, Boyan K, Acker, Till

“…Hypoxia is a common feature of solid tumors, which controls multiple aspects of cancer progression. One important function of hypoxia and the hypoxia-inducible…”
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PHD3 Controls Lung Cancer Metastasis and Resistance to EGFR Inhibitors through TGFα by Dopeso, Higinio, Jiao, Hui-Ke, Cuesta, Angel M, Henze, Anne-Theres, Jurida, Liane, Kracht, Michael, Acker-Palmer, Amparo, Garvalov, Boyan K, Acker, Till

“…Lung cancer is the leading cause of cancer-related death worldwide, in large part due to its high propensity to metastasize and to develop therapy resistance…”
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Cancer stem cells: a new framework for the design of tumor therapies by Garvalov, Boyan K., Acker, Till

“…Modern tumor therapy has achieved considerable progress, but many tumors remain refractory to treatment or relapse following initial remission. Recent evidence…”
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Cellular oxygen sensing need in CNS function: physiological and pathological implications by Acker, Till, Acker, Helmut

“…Structural and functional integrity of brain function profoundly depends on a regular oxygen and glucose supply. Any disturbance of this supply becomes life…”
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Beyond ribosome biogenesis: noncoding nucleolar RNAs in physiology and tumor biology by Böğürcü-Seidel, Nuray, Ritschel, Nadja, Acker, Till, Németh, Attila

“…The nucleolus, the largest subcompartment of the nucleus, stands out from the nucleoplasm due to its exceptionally high local RNA and low DNA concentrations…”
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Oligosarcomas, IDH-mutant are distinct and aggressive by Suwala, Abigail K., Felix, Marius, Friedel, Dennis, Stichel, Damian, Schrimpf, Daniel, Hinz, Felix, Hewer, Ekkehard, Schweizer, Leonille, Dohmen, Hildegard, Pohl, Ute, Staszewski, Ori, Korshunov, Andrey, Stein, Marco, Wongsurawat, Thidathip, Cheunsuacchon, Pornsuk, Sathornsumetee, Sith, Koelsche, Christian, Turner, Clinton, Le Rhun, Emilie, Mühlebner, Angelika, Schucht, Philippe, Özduman, Koray, Ono, Takahiro, Shimizu, Hiroaki, Prinz, Marco, Acker, Till, Herold-Mende, Christel, Kessler, Tobias, Wick, Wolfgang, Capper, David, Wesseling, Pieter, Sahm, Felix, von Deimling, Andreas, Hartmann, Christian, Reuss, David E.

“…Oligodendrogliomas are defined at the molecular level by the presence of an IDH mutation and codeletion of chromosomal arms 1p and 19q. In the past, case…”
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Feedback regulators of hypoxia-inducible factors and their role in cancer biology by Henze, Anne-Theres, Acker, Till

“…Malignant tumors are characterized by regions of low oxygen concentration (hypoxia). The hypoxic tumor microenvironment contributes to tumor progression by…”
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Implications of Oxygen Homeostasis for Tumor Biology and Treatment by Garvalov, Boyan K, Acker, Till

“…Tumors serve as a prototype system to study the role of the hypoxic microenvironment and gain insight in the regulation oxygen homeostasis. A series of…”
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Rise and fall of peroxisomes during Alzheimer´s disease: a pilot study in human brains by Semikasev, Eugen, Ahlemeyer, Barbara, Acker, Till, Schänzer, Anne, Baumgart-Vogt, Eveline

“…Peroxisomes are eukaryotic organelles that rapidly change in number depending on the metabolic requirement of distinct cell types and tissues. In the brain,…”
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Reduced Rate of Inpatient Hospital Admissions in 18 German University Hospitals During the COVID-19 Lockdown by Kapsner, Lorenz A, Kampf, Marvin O, Seuchter, Susanne A, Gruendner, Julian, Gulden, Christian, Mate, Sebastian, Mang, Jonathan M, Schüttler, Christina, Deppenwiese, Noemi, Krause, Linda, Zöller, Daniela, Balig, Julien, Fuchs, Timo, Fischer, Patrick, Haverkamp, Christian, Holderried, Martin, Mayer, Gerhard, Stenzhorn, Holger, Stolnicu, Ana, Storck, Michael, Storf, Holger, Zohner, Jochen, Kohlbacher, Oliver, Strzelczyk, Adam, Schüttler, Jürgen, Acker, Till, Boeker, Martin, Kaisers, Udo X, Kestler, Hans A, Prokosch, Hans-Ulrich

“…The COVID-19 pandemic has caused strains on health systems worldwide disrupting routine hospital services for all non-COVID patients. Within this retrospective…”
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LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem-Like Cells by Nakata, Susumu, Campos, Benito, Bageritz, Josephine, Lorenzo Bermejo, Justo, Becker, Natalia, Engel, Felix, Acker, Till, Momma, Stefan, Herold-Mende, Christel, Lichter, Peter, Radlwimmer, Bernhard, Goidts, Violaine

“…In various types of cancers including glioblastoma, accumulating evidence show the existence of cancer stem‐like cells (CSCs), characterized by stem cell…”
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Prolyl Hydroxylases 2 and 3 Act in Gliomas as Protective Negative Feedback Regulators of Hypoxia-Inducible Factors by HENZE, Anne-Theres, RIEDEL, Johanna, DIEM, Tanja, WENNER, Julia, FLAMME, Ingo, POUYSEGGUR, Jacques, PLATE, Karl H, ACKER, Till

“…Adaptive responses to hypoxia in tumors are transcriptionally regulated by the hypoxia inducible factors (HIF-1alpha/HIF-2alpha), which are tightly controlled…”
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Outcome of whole brain irradiation with a dose-escalated simultaneous-integrated boost in patients with multiple large and/or diffuse brain metastases: real live data and review of the literature by Agolli, Linda, Nicosia, Luca, Hilger, Thomas, Iancu, Gheorghe, Exeli, Ann-Katrin, Eul, Bastian, Struffert, Tobias, Acker, Till, Habermehl, Daniel

“…Background We retrospectively investigate feasibility and safety of whole brain radiotherapy (WBRT) including a simultaneous-integrated boost technique…”
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Integrating clinical decision support systems for pharmacogenomic testing into clinical routine - a scoping review of designs of user-system interactions in recent system development by Hinderer, Marc, Boeker, Martin, Wagner, Sebastian A, Lablans, Martin, Newe, Stephanie, Hülsemann, Jan L, Neumaier, Michael, Binder, Harald, Renz, Harald, Acker, Till, Prokosch, Hans-Ulrich, Sedlmayr, Martin

“…Pharmacogenomic clinical decision support systems (CDSS) have the potential to help overcome some of the barriers for translating pharmacogenomic knowledge…”
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Continued response off treatment after BRAF inhibition in refractory hairy cell leukemia by Dietrich, Sascha, Hüllein, Jennifer, Hundemer, Michael, Lehners, Nicola, Jethwa, Alexander, Capper, David, Acker, Till, Garvalov, Boyan K, Andrulis, Mindaugas, Blume, Carolin, Schulte, Christoph, Mandel, Thomas, Meissner, Julia, Fröhling, Stefan, von Kalle, Christof, Glimm, Hanno, Ho, Anthony D, Zenz, Thorsten

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Case Report of Complete Radiological Response of a Thalamic Glioblastoma After Treatment With Proton Therapy Followed by Temozolomide and Tumor-Treating Fields by Stein, Marco, Dohmen, Hildegard, Wölk, Bernhard, Eberle, Fabian, Kolodziej, Malgorzata, Acker, Till, Uhl, Eberhard, Jensen, Alexandra

“…Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults. We present a case of a 42-year-old male patient presenting with headache…”
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