Search Results - "ACKER, H"

CD56 in the Immune System: More Than a Marker for Cytotoxicity? by Van Acker, Heleen H, Capsomidis, Anna, Smits, Evelien L, Van Tendeloo, Viggo F

“…Over the past years, the phenotypic and functional boundaries distinguishing the main cell subsets of the immune system have become increasingly blurred. In…”
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Bisphosphonates for cancer treatment: Mechanisms of action and lessons from clinical trials by Van Acker, Heleen H, Anguille, Sébastien, Willemen, Yannick, Smits, Evelien L, Van Tendeloo, Viggo F

“…A growing body of evidence points toward an important anti-cancer effect of bisphosphonates, a group of inexpensive, safe, potent, and long-term stable…”
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Chimeric Antigen Receptor-Modified T Cell Therapy in Multiple Myeloma: Beyond B Cell Maturation Antigen by Timmers, Marijke, Roex, Gils, Wang, Yuedi, Campillo-Davo, Diana, Van Tendeloo, Viggo F I, Chu, Yiwei, Berneman, Zwi N, Luo, Feifei, Van Acker, Heleen H, Anguille, Sébastien

“…Chimeric antigen receptor (CAR)-modified T cell therapy is a rapidly emerging immunotherapeutic approach that is revolutionizing cancer treatment. The…”
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Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells by Van Acker, Heleen H, Anguille, Sébastien, Willemen, Yannick, Van den Bergh, Johan M, Berneman, Zwi N, Lion, Eva, Smits, Evelien L, Van Tendeloo, Viggo F

“…Adoptive immunotherapy is gaining momentum to fight malignancies, whereby γδ T cells have received recent attention as an alternative cell source as to natural…”
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Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner by Anguille, Sébastien, Van Acker, Heleen H, Van den Bergh, Johan, Willemen, Yannick, Goossens, Herman, Van Tendeloo, Viggo F, Smits, Evelien L, Berneman, Zwi N, Lion, Eva

“…The contribution of natural killer (NK) cells to the treatment efficacy of dendritic cell (DC)-based cancer vaccines is being increasingly recognized. Much…”
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Interleukin-15-Cultured Dendritic Cells Enhance Anti-Tumor Gamma Delta T Cell Functions through IL-15 Secretion by Van Acker, Heleen H, Anguille, Sébastien, De Reu, Hans, Berneman, Zwi N, Smits, Evelien L, Van Tendeloo, Viggo F

“…Dendritic cell (DC) vaccination can be an effective post-remission therapy for acute myeloid leukemia (AML). Yet, current DC vaccines do not encompass the…”
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The good, the bad and the ugly in oxygen-sensing: ROS, cytochromes and prolyl-hydroxylases by Acker, Till, Fandrey, Joachim, Acker, Helmut

“…Current concepts of cellular oxygen-sensing include an isoform of the neutrophil NADPH oxidase, different electron carrier units of the mitochondrial electron…”
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Laser-induced vapor nanobubbles improve diffusion in biofilms of antimicrobial agents for wound care by Teirlinck, E., Fraire, J.C., Van Acker, H., Wille, J., Swimberghe, R., Brans, T., Xiong, R., Meire, M., De Moor, R.J.G., De Smedt, S.C., Coenye, T., Braeckmans, K.

“…Being responsible for delayed wound healing, the presence of biofilms in infected wounds leads to chronic, and difficult to treat infections. One of the…”
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Type I cell ROS kinetics under hypoxia in the intact mouse carotid body ex vivo: a FRET-based study by Bernardini, A, Brockmeier, U, Metzen, E, Berchner-Pfannschmidt, U, Harde, E, Acker-Palmer, A, Papkovsky, D, Acker, H, Fandrey, J

“…Reactive oxygen species (ROS) mainly originating from NADPH oxidases have been shown to be involved in the carotid body (CB) oxygen-sensing cascade. For…”
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Two‐photon fluorescence absorption and emission spectra of dyes relevant for cell imaging by Bestvater, F., Spiess, E., Stobrawa, G., Hacker, M., Feurer, T., Porwol, T., Berchner‐Pfannschmidt, U., Wotzlaw, C., Acker, H.

“…Summary Two‐photon absorption and emission spectra for fluorophores relevant in cell imaging were measured using a 45 fs Ti:sapphire laser, a continuously…”
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Human blood myeloid and plasmacytoid dendritic cells cross activate each other and synergize in inducing NK cell cytotoxicity by van Beek, Jasper J. P., Gorris, Mark A. J., Sköld, Annette E., Hatipoglu, Ibrahim, Van Acker, Heleen H., Smits, Evelien L., de Vries, I. Jolanda M., Bakdash, Ghaith

“…Human blood dendritic cells (DCs) hold great potential for use in anticancer immunotherapies. CD1c + myeloid DCs and plasmacytoid DCs (pDCs) have been…”
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Chimeric Antigen Receptor-Engineered Human Gamma Delta T Cells: Enhanced Cytotoxicity with Retention of Cross Presentation by Capsomidis, Anna, Benthall, Gabriel, Van Acker, Heleen H., Fisher, Jonathan, Kramer, Anne M., Abeln, Zarah, Majani, Yvonne, Gileadi, Talia, Wallace, Rebecca, Gustafsson, Kenth, Flutter, Barry, Anderson, John

“…Gamma delta T (γδT) lymphocytes are primed for rapid function, including cytotoxicity toward cancer cells, and are a component of the immediate stress…”
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How metabolism bridles cytotoxic CD8+ T cells through epigenetic modifications by Van Acker, Heleen H., Ma, Shixin, Scolaro, Tommaso, Kaech, Susan M., Mazzone, Massimiliano

“…In the direct competition for metabolic resources between cancer cells and tumor-infiltrating CD8+ T cells, the latter are bound to lose out. These effector…”
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BDCA1+CD14+ Immunosuppressive Cells in Cancer, a Potential Target? by van Ee, Thomas J, Van Acker, Heleen H, van Oorschot, Tom G, Van Tendeloo, Viggo F, Smits, Evelien L, Bakdash, Ghaith, Schreibelt, Gerty, de Vries, I Jolanda M

“…Dendritic cell (DC) vaccines show promising effects in cancer immunotherapy. However, their efficacy is affected by a number of factors, including (1) the…”
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Two‐photon excitation and emission spectra of the green fluorescent protein variants ECFP, EGFP and EYFP by SPIESS, E., BESTVATER, F., HECKEL‐POMPEY, A., TOTH, K., HACKER, M., STOBRAWA, G., FEURER, T., WOTZLAW, C., BERCHNER‐PFANNSCHMIDT, U., PORWOL, T., ACKER, H.

“…Summary Two‐photon (TP) excitation (820–1150 nm) and emission (280–700 nm) spectra for the fluorescent proteins (FPs) ECFP3, EGFP3 and EYFP3 produced in human…”
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Dilated cardiomyopathy caused by a novel TNNT2 mutation—Added value of genetic testing in the correct identification of affected subjects by Van Acker, H, De Sutter, J, Vandekerckhove, K, de Ravel, Th. JL, Verhaaren, H, De Backer, J

“…Abstract Diagnosing familial dilated cardiomyopathy requires careful family history taking and clinical evaluation in first degree relatives. Based on the…”
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Dendritic Cells as Pharmacological Tools for Cancer Immunotherapy by Anguille, Sébastien, Smits, Evelien L, Bryant, Christian, Van Acker, Heleen H, Goossens, Herman, Lion, Eva, Fromm, Phillip D, Hart, Derek N, Van Tendeloo, Viggo F, Berneman, Zwi N

“…Although the earliest—rudimentary—attempts at exploiting the immune system for cancer therapy can be traced back to the late 18th Century, it was not until the…”
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The quiet (energy) revolution: Analysing the dissemination of photovoltaic power systems in Kenya by Acker, Richard H, Kammen, Daniel M

“…The widespread introduction and adoption of renewable energy technologies remains high on virtually every national development policy agenda; renewable energy…”
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The role of the common gamma-chain family cytokines in γδ T cell-based anti-cancer immunotherapy by Van Acker, Heleen H., Campillo-Davo, Diana, Roex, Gils, Versteven, Maarten, Smits, Evelien L., Van Tendeloo, Viggo F.

“…•The cytokines of the common gamma-chain receptor family all have their unique effects on γδ T cells.•Interleukin-15-activated γδ T cells arise as strong…”
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Immunohistochemical demonstration of four subunits of neutrophil NAD(P)H oxidase in type I cells of carotid body by Kummer, W, Acker, H

“…We demonstrate, by means of immunohistochemistry, that type I cells of human, guinea pig, and rat carotid bodies react with antisera raised against the…”
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