Search Results - "ACHIKE, F. I"

Tetrandrine and related bis—benzylisoquinoline alkaloids from medicinal herbs：cardiovascular effects and mechanisms of action by Kwan, Chiu-Yin, Achike, F I

“…Tetrandrine(TET),a bis-benzylisoquinoline alkaloid purified and identified an active ingredient in a Chinese medicinal herb,Radix Stephanae tetrandrae,has been…”
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General and URTI-specific antibiotic prescription rates in a Malaysian primary care setting by Teng, C.L., Achike, F.I., Phua, K.L., Norhayati, Y., Nurjahan, M.I., Nor, A.H., Koh, C.N.

“…Antibiotic prescribing by primary care doctors has received renewed interest due to the continuing emergence of antibiotic resistance and the attendant cost to…”
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Effect of des-aspartate-angiotensin I on the actions of angiotensin II in the isolated renal and mesenteric vasculature of hypertensive and STZ-induced diabetic rats by Dharmani, M., Mustafa, M.R., Achike, F.I., Sim, M.K.

“…The present study investigated the action of des-aspartate-angiotensin I (DAA-I) on the pressor action of angiotensin II in the renal and mesenteric…”
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Information Overload in the Teaching of Pharmacology by Achike, Francis I., Ogle, Clive W.

“…Medical students are usually drawn from the best of students, but it is not unusual to see these brilliant students fail their exams or even dismissed from…”
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Mechanisms underlining gender differences in Phenylephrine contraction of normoglycaemic and short-term Streptozotocin-induced diabetic WKY rat aorta by Aloysius, U.I, Achike, F.I, Mustafa, M.R

“…Abstract The female gender reduces the risk, but succumbs more to cardiovascular disease. The hypothesis that short-term (8 weeks) Streptozotocin-induced…”
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Influence of stimulation parameters on the release of adenosine, lactate and CO2 from contracting dog gracilis muscle by Achike, F I, Ballard, H J

“…1. The addition of adenosine, CO2 and lactate to the venous blood draining an isolated constant-flow perfused gracilis muscle was studied in anaesthetized and…”
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Involvement of AT(1) angiotensin receptors in the vasomodulatory effect of des-aspartate-angiotensin I in the rat renal vasculature by Dharmani, M, Mustafa, M R, Achike, F I, Sim, M K

“…Angiotensin II is known to act primarily on the angiotensin AT(1) receptors to mediate its physiological and pathological actions. Des-aspartate-angiotensin I…”
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Involvement of AT1 angiotensin receptors in the vasomodulatory effect of des-aspartate-angiotensin I in the rat renal vasculature by DHARMANI, M, MUSTAFA, M. R, ACHIKE, F. I, SIM, M. K

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Mechanism of action of prostaglandin E2 in the dog skeletal muscle circulation by Ballard, H J, Achike, F I

“…To determine whether prostaglandin E2 (PGE2) influences the dog skeletal muscle circulation by a direct action on the vascular smooth muscle or via pre- or…”
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Hydrogen peroxide modulates angiotensin II-induced contraction of mesenteric arteries from streptozotocin-induced diabetic rats by Chin, L.C, Achike, F.I, Mustafa, M.R

“…Abstract Hydrogen peroxide (H2 O2 ) contributes in the regulation of vascular tone, especially in pathological states. The role of H2 O2 and superoxide anion…”
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Cardiovascular responses to verapamil and nifedipine in hypoventilated and hyperventilated rats by Achike, Francis I., Dai, Soter

“…1 The influence of hypoventilation or hyperventilation on blood pressure and pulse rate responses to verapamil and nifedipine was studied in…”
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Influence of pH changes on the actions of verapamil on cardiac excitation-contraction coupling by Achike, F I, Dai, S

“…Langendorff preparations of Sprague-Dawley rat hearts were perfused with calcium-free Krebs solution of pH 7.48 (control), 7.26 (acidosis) or 7.69 (alkalosis)…”
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Pain morbidity in primary care - preliminary observations from two different primary care settings by Zailinawati, A H, Teng, C L, Kamil, M A, Achike, F I, Koh, C N

“…The prevalence of pain complaints as a reason for patient-doctor encounters in the local primary care setting is unknown. We performed a cross-sectional survey…”
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Many roads lead to Rome--is that true of the teaching and learning of pharmacology? Lessons from three medical schools in Malaysia by Sim, S M, Achike, F I, Geh, S L

“…In Malaysia many new medical schools (both public and private) have been set up in the last 12 years. As a result of global changes and local adjustments made…”
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Modifying antibiotic prescribing: the effectiveness of academic detailing plus information leaflet in a Malaysian primary care setting by Teng, C L, Achike, F I, Phua, K L, Nurjahan, M I, Mastura, I, Asiah, H Nor, Mariam, A M, Narayanan, S, Norsiah, A, Sabariah, I, Shariah, I, Rokiah, K Siti, Zubaidah, M A Siti, Koh, C N, Rosnah, I

“…We assessed the effectiveness of an educational intervention in reducing antibiotic prescribing in public primary care clinics in Malaysia. Twenty-nine medical…”
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Cardiovascular responses to nifedipine in anaesthetized rats with abnormal blood gas/pH levels by Achike, F I, Dai, S

“…1. Blood pressure and pulse rate responses to intravenously (i.v.) administered nifedipine were studied in chloralose-anaesthetized rats subjected to…”
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Blood pH and the actions of nifedipine on cardiac excitation-contraction coupling by Achike, F I, Dai, S, Ogle, C W

“…Hearts from male Sprague-Dawley rats were perfused, by the Lagendorff method, with calcium-free Krebs solution (containing either adrenaline or a high level of…”
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EFFECTS OF ACIDOSIS OR ALKALOSIS ON THE ACTIONS OF NIFEDIPINE ON EXCITATION‐CONTRACTION COUPLING IN THE RAT TAIL ARTERY by Achike, Francis I., Mohamad, Rohaini, Dai, Soter, Ogle, Clive W.

“…SUMMARY 1. The clinical success of calcium channel blockers in the management of organ ischaemia is less than theoretically anticipated. Blood gas/pH changes…”
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Influence of pH changes on the actions of verapamil on vascular excitation-contraction coupling by Achike, Francis I., Dai, Soter, Ogle, Clive W.

“…We have previously shown that pH changes alter the cardiovascular responses to verapamil in rat, in vivo and in isolated rat heart. The current study…”
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Influence of extracellular pH, sodium propionate and trimethylamine on excitation-contraction coupling in the rat tail artery by Achike, F I, Ballard, H J, Ogle, C W

“…1. The effects of extracellular or intracellular pH changes on agonist- or depolarization-induced contractions of the rat tail artery were investigated. 2…”
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