Search Results - "ACEVEDO, A."

The MEK/ERK Network as a Therapeutic Target in Human Cancer by Barbosa, Renee, Acevedo, Lucila A, Marmorstein, Ronen

“…The RAS-RAF-MEK-ERK pathway is the most well-studied of the MAPK cascades and is critical for cell proliferation, differentiation, and survival. Abnormalities…”
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Next generation of immune checkpoint inhibitors and beyond by Marin-Acevedo, Julian A, Kimbrough, ErinMarie O, Lou, Yanyan

“…The immune system is the core defense against cancer development and progression. Failure of the immune system to recognize and eliminate malignant cells plays…”
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Emerging insights into hypothalamic‐pituitary‐gonadal axis regulation and interaction with stress signalling by Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., Laconi, M.

“…Reproduction and fertility are regulated via hormones of the hypothalamic‐pituitary‐gonadal (HPG) axis. Control of this reproductive axis occurs at all levels,…”
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Amphibian fungal panzootic causes catastrophic and ongoing loss of biodiversity by Scheele, Ben C, Pasmans, Frank, Skerratt, Lee F, Berger, Lee, Martel, An, Beukema, Wouter, Acevedo, Aldemar A, Burrowes, Patricia A, Carvalho, Tamilie, Catenazzi, Alessandro, De la Riva, Ignacio, Fisher, Matthew C, Flechas, Sandra V, Foster, Claire N, Frías-Álvarez, Patricia, Garner, Trenton W J, Gratwicke, Brian, Guayasamin, Juan M, Hirschfeld, Mareike, Kolby, Jonathan E, Kosch, Tiffany A, La Marca, Enrique, Lindenmayer, David B, Lips, Karen R, Longo, Ana V, Maneyro, Raúl, McDonald, Cait A, Mendelson, 3rd, Joseph, Palacios-Rodriguez, Pablo, Parra-Olea, Gabriela, Richards-Zawacki, Corinne L, Rödel, Mark-Oliver, Rovito, Sean M, Soto-Azat, Claudio, Toledo, Luís Felipe, Voyles, Jamie, Weldon, Ché, Whitfield, Steven M, Wilkinson, Mark, Zamudio, Kelly R, Canessa, Stefano

“…Anthropogenic trade and development have broken down dispersal barriers, facilitating the spread of diseases that threaten Earth's biodiversity. We present a…”
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Next generation of immune checkpoint therapy in cancer: new developments and challenges by Marin-Acevedo, Julian A, Dholaria, Bhagirathbhai, Soyano, Aixa E, Knutson, Keith L, Chumsri, Saranya, Lou, Yanyan

“…Immune checkpoints consist of inhibitory and stimulatory pathways that maintain self-tolerance and assist with immune response. In cancer, immune checkpoint…”
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Teaching quantitative ecology online: An evidence‐based prescription of best practices by Acevedo, Miguel A.

“…Quantitative skills are becoming central to the undergraduate and graduate curriculum in ecology and evolutionary biology. While previous studies acknowledge…”
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Oral Manifestations in Patients with COVID-19: A Living Systematic Review by Amorim dos Santos, J., Normando, A.G.C., Carvalho da Silva, R.L., Acevedo, A.C., De Luca Canto, G., Sugaya, N., Santos-Silva, A.R., Guerra, E.N.S.

“…This living systematic review aims to summarize evidence on the prevalence of oral signs and symptoms in patients with COVID-19. The review was reported per…”
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Image processing and machine learning in the morphological analysis of blood cells by Rodellar, J., Alférez, S., Acevedo, A., Molina, A., Merino, A.

“…Introduction This review focuses on how image processing and machine learning can be useful for the morphological characterization and automatic recognition of…”
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Cancer immunotherapy beyond immune checkpoint inhibitors by Marin-Acevedo, Julian A, Soyano, Aixa E, Dholaria, Bhagirathbhai, Knutson, Keith L, Lou, Yanyan

“…Malignant cells have the capacity to rapidly grow exponentially and spread in part by suppressing, evading, and exploiting the host immune system…”
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Comparison of five chickpea varieties, optimization of hydrolysates production and evaluation of biomarkers for type 2 diabetes by Acevedo Martínez, Karla A., Gonzalezde Mejia, Elvira

“…[Display omitted] •Hydrolysis with bromelain produced peptides with 93% DPPIV inhibition.•Peptides SFDLPAL and EVLSEVSF from legumins and albumins inhibited…”
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Genome-wide ultraconserved elements resolve phylogenetic relationships and biogeographic history among Neotropical leaf-nosed bats in the genus Anoura (Phyllostomidae) by Calderón-Acevedo, Camilo A., Bagley, Justin C., Muchhala, Nathan

“…[Display omitted] •Tailless bats in the genus Anoura are important pollinators of Neotropical forests.•Using UCEs, we generate a new time-calibrated molecular…”
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Geographic differences in body size distributions underlie food web connectance of tropical forest mammals by Beaudrot, Lydia, Acevedo, Miguel A., Gorczynski, Daniel, Harris, Nyeema C.

“…Understanding variation in food web structure over large spatial scales is an emerging research agenda in food web ecology. The density of predator–prey links…”
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Binding Energy Partition of Promising IRAK‐4 Inhibitor (Zimlovisertib) for the Treatment of COVID‐19 Pneumonia by Zapata‐Acevedo, César A., Guevara‐Vela, José Manuel, Popelier, Paul L. A., Rocha‐Rinza, Tomás

“…The technique of Fragment‐Based Drug Design (FBDD) considers the interactions of different moieties of molecules with biological targets for the rational…”
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Oxidation mechanisms of amoxicillin and paracetamol in the photo-Fenton solar process by Hinojosa Guerra, M.M., Oller Alberola, I., Malato Rodriguez, S., Agüera López, A., Acevedo Merino, A., Quiroga Alonso, J.M.

“…The present study shows the results of solar photo-Fenton oxidation of paracetamol (PCT) and amoxicillin (AMX). Fe2(SO4)3 was used as the source of iron and…”
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Role of Extracellular Trap Release During Bacterial and Viral Infection by Schultz, Bárbara M, Acevedo, Orlando A, Kalergis, Alexis M, Bueno, Susan M

“…Neutrophils are innate immune cells that play an essential role during the clearance of pathogens that can release chromatin structures coated by several…”
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Indoor tanning prevalence after the International Agency for Research on Cancer statement on carcinogenicity of artificial tanning devices: systematic review and meta‐analysis by Rodriguez‐Acevedo, A.J., Green, A.C., Sinclair, C., Deventer, E., Gordon, L.G.

“…Summary Background Exposure to artificial tanning devices is carcinogenic to humans, and government regulations to restrict or ban indoor tanning appear to be…”
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Modulation of motor behavior by the mesencephalic locomotor region by Dautan, Daniel, Kovács, Adrienn, Bayasgalan, Tsogbadrakh, Diaz-Acevedo, Miguel A., Pal, Balazs, Mena-Segovia, Juan

“…The mesencephalic locomotor region (MLR) serves as an interface between higher-order motor systems and lower motor neurons. The excitatory module of the MLR is…”
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The CCL2/CCR2 axis is critical to recruiting macrophages into acellular nerve allograft bridging a nerve gap to promote angiogenesis and regeneration by Pan, Deng, Acevedo-Cintrón, Jesús A., Sayanagi, Junichi, Snyder-Warwick, Alison K., Mackinnon, Susan E., Wood, Matthew D.

“…Acellular nerve allografts (ANAs) are increasingly used to repair nerve gaps following injuries. However, these nerve scaffolds have yet to surpass the…”
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Integrating presence‐only and detection/non‐detection data to estimate distributions and expected abundance of difficult‐to‐monitor species on a landscape‐scale by Twining, Joshua P., Fuller, Angela K., Sun, Catherine C., Calderón‐Acevedo, Camilo A., Schlesinger, Matthew D., Berger, Melanie, Kramer, David, Frair, Jacqueline L.

“…Estimating species distribution and abundance is foundational to effective management and conservation. Using an integrated species distribution model that…”
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Limited Nerve Regeneration across Acellular Nerve Allografts (ANAs) Coincides with Changes in Blood Vessel Morphology and the Development of a Pro-Inflammatory Microenvironment by Acevedo Cintrón, Jesús A, Hunter, Daniel A, Schellhardt, Lauren, Pan, Deng, Mackinnon, Susan E, Wood, Matthew D

“…The use of acellular nerve allografts (ANAs) to reconstruct long nerve gaps (>3 cm) is associated with limited axon regeneration. To understand why ANA length…”
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