Search Results - "AC Siemieniuk, Reed"
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Clopidogrel plus aspirin versus aspirin alone for acute minor ischaemic stroke or high risk transient ischaemic attack: systematic review and meta-analysis
Published in BMJ (Online) (18-12-2018)“…To assess the effectiveness and safety of dual agent antiplatelet therapy combining clopidogrel and aspirin to prevent recurrent thrombotic and bleeding events…”
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2
The persisting burden of invasive pneumococcal disease in HIV patients: an observational cohort study
Published in BMC infectious diseases (11-11-2011)“…The increasing use of highly active antiretroviral therapy (HAART) and pneumococcal immunization along with shifting community exposures may have altered the…”
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Corticosteroids in Patients Hospitalized With Community-Acquired Pneumonia: Systematic Review and Individual Patient Data Metaanalysis
Published in Clinical infectious diseases (18-01-2018)“…Our aim was to evaluate the benefits and harms of adjunctive corticosteroids in adults hospitalized with community-acquired pneumonia (CAP) using individual…”
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4
Increasing HIV subtype diversity and its clinical implications in a sentinel North American population
Published in The Canadian journal of infectious diseases & medical microbiology (2013)“…HIV-1 is a highly diverse virus; subtypes may exhibit differences in rates of transmission, disease progression, neurotoxicity, antiretroviral treatment…”
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5
Corticosteroid Therapy for Patients Hospitalized With Community-Acquired Pneumonia: A Systematic Review and Meta-analysis
Published in Annals of internal medicine (06-10-2015)“…Community-acquired pneumonia (CAP) is common and often severe. To examine the effect of adjunctive corticosteroid therapy on mortality, morbidity, and duration…”
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Comparative efficacy and safety of alternative glucocorticoids regimens in patients with ANCA-associated vasculitis: a systematic review
Published in BMJ open (25-02-2022)“…ObjectiveTo compare the efficacy and safety of alternative glucocorticoids (GCs) regimens as induction therapy for patients with antineutrophil cytoplasmic…”
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7
Antiretroviral resistance testing in HIV-positive people
Published in Cochrane database of systematic reviews (09-11-2018)“…Resistance to antiretroviral therapy (ART) among people living with human immunodeficiency virus (HIV) compromises treatment effectiveness, often leading to…”
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Transitioning to HIV Pre-Exposure Prophylaxis (PrEP) from Non-Occupational Post-Exposure Prophylaxis (nPEP) in a Comprehensive HIV Prevention Clinic: A Prospective Cohort Study
Published in AIDS patient care and STDs (01-08-2015)“…The uptake of pre-exposure prophylaxis (PrEP) for HIV prevention remains low. We hypothesized that a high proportion of patients presenting for HIV…”
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Implementing an intimate partner violence (IPV) screening protocol in HIV care
Published in AIDS patient care and STDs (01-03-2015)“…HIV and intimate partner violence (IPV) epidemics propagate and interact in a syndemic fashion contributing to excess burden of disease and poorer health…”
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10
Domestic violence screening: prevalence and outcomes in a Canadian HIV population
Published in AIDS patient care and STDs (01-12-2010)“…There is a strong association between domestic violence victimization and HIV infection. This may lead to poor health outcomes including mental health…”
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11
Interpersonal Violence and Its Impact on Persons Living With HIV: A Social Work Response
Published in Journal of HIV/AIDS & social services (03-07-2015)“…The burden of interpersonal violence (IPV) among those living with HIV is significant. At the Southern Alberta Clinic in Calgary, Alberta, there has been…”
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12
GRADE approach to rate the certainty from a network meta-analysis: addressing incoherence
Published in Journal of clinical epidemiology (01-04-2019)“…This article presents official guidance from the Grading of Recommendations Assessments, Development, and Evaluation (GRADE) working group on how to address…”
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13
Compelling evidence from meta-epidemiological studies demonstrates overestimation of effects in randomized trials that fail to optimize randomization and blind patients and outcome assessors
Published in Journal of clinical epidemiology (01-01-2024)“…To investigate the impact of potential risk of bias elements on effect estimates in randomized trials. We conducted a systematic survey of meta-epidemiological…”
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A novel framework for incorporating patient values and preferences in making guideline recommendations: guideline panel surveys
Published in Journal of clinical epidemiology (01-09-2023)“…Universally acknowledged standards for trustworthy guidelines include the necessity to ground recommendations in patient values and preferences. When…”
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Qualitative study of guideline panelists: innovative surveys provided valuable insights regarding patient values and preferences
Published in Journal of clinical epidemiology (01-09-2023)“…To explore guideline panelists' understanding of panel surveys for eliciting panels' inferences regarding patient values and preferences, and the influence of…”
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Instruments assessing risk of bias of randomized trials frequently included items that are not addressing risk of bias issues
Published in Journal of clinical epidemiology (01-12-2022)“…To establish whether items included in instruments published in the last decade assessing risk of bias of randomized controlled trials (RCTs) are indeed…”
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Addition of Ezetimibe to statins for patients at high cardiovascular risk: Systematic review of patient‐important outcomes
Published in Journal of evaluation in clinical practice (01-02-2018)“…Ezetimibe is widely used in combination with statins to reduce low‐density lipoprotein. We sought to examine the impact of ezetimibe when added to statins on…”
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