Search Results - "ABREU, T"

The bipolarity of light and dark: A review on Bipolar Disorder and circadian cycles by Abreu, T, Bragança, M

“…Abstract Background Bipolar Disorder is characterized by episodes running the full mood spectrum, from mania to depression. Between mood episodes, residual…”
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Probiotic improves symptomatic and viral clearance in Covid19 outpatients: a randomized, quadruple-blinded, placebo-controlled trial by Gutiérrez-Castrellón, Pedro, Gandara-Martí, Tania, Abreu Y Abreu, Ana T., Nieto-Rufino, Cesar D., López-Orduña, Eduardo, Jiménez-Escobar, Irma, Jiménez-Gutiérrez, Carlos, López-Velazquez, Gabriel, Espadaler-Mazo, Jordi

“…Intestinal bacteria may influence lung homeostasis via the gut-lung axis. We conducted a single-center, quadruple-blinded, randomized trial in adult…”
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Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis by Sands, Bruce E, Sandborn, William J, Panaccione, Remo, O’Brien, Christopher D, Zhang, Hongyan, Johanns, Jewel, Adedokun, Omoniyi J, Li, Katherine, Peyrin-Biroulet, Laurent, Van Assche, Gert, Danese, Silvio, Targan, Stephan, Abreu, Maria T, Hisamatsu, Tadakazu, Szapary, Philippe, Marano, Colleen

“…Patients with moderate-to-severe ulcerative colitis were randomly assigned to receive placebo or induction doses of ustekinumab. Patients who had a response to…”
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JAK1 Inhibition to Treat Crohn’s Disease by Abreu, Maria T.

“…This editorial describes the science behind clinical trials that tested upadacitinib, a drug that targets JAK1, for efficacy in treating Crohn’s disease…”
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Gastrointestinal Malignancy and the Microbiome by Abreu, Maria T, Peek, Richard M

“…Microbial species participate in the genesis of a substantial number of malignancies—in conservative estimates, at least 15% of all cancer cases are…”
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STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD by Turner, Dan, Ricciuto, Amanda, Lewis, Ayanna, D’Amico, Ferdinando, Dhaliwal, Jasbir, Griffiths, Anne M., Bettenworth, Dominik, Sandborn, William J., Sands, Bruce E., Reinisch, Walter, Schölmerich, Jürgen, Bemelman, Willem, Danese, Silvio, Mary, Jean Yves, Rubin, David, Colombel, Jean-Frederic, Peyrin-Biroulet, Laurent, Dotan, Iris, Abreu, Maria T., Dignass, Axel

“…The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) initiative of the International Organization for the Study of Inflammatory Bowel…”
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Exercise attenuates PCB-induced changes in the mouse gut microbiome by Choi, Jeong June, Eum, Sung Yong, Rampersaud, Evadnie, Daunert, Sylvia, Abreu, Maria T, Toborek, Michal

“…The gut microbiome, a dynamic bacterial community that interacts with the host, is integral to human health because it regulates energy metabolism and immune…”
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A Comprehensive Literature Review and Expert Consensus Statement on Therapeutic Drug Monitoring of Biologics in Inflammatory Bowel Disease by Cheifetz, Adam S., Abreu, Maria T., Afif, Waqqas, Cross, Raymond K., Dubinsky, Marla C., Loftus, Edward V., Osterman, Mark T., Saroufim, Ariana, Siegel, Corey A., Yarur, Andres J., Melmed, Gil Y., Papamichael, Konstantinos

“…Therapeutic drug monitoring (TDM) of biologics is a rapidly evolving field. We aimed to provide a consensus statement regarding the clinical utility of TDM for…”
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Cognitive-behavioral therapy for bipolar disorder by Abreu, T

“…Introduction Bipolar disorder is a chronic disease with a major impact on patient's functioning and quality of life, not only during episodes of…”
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DDS Perspective: My Take on Therapeutic Drug Monitoring in IBD by Abreu, Maria T.

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Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids by Ramesh, Radha, Kozhaya, Lina, McKevitt, Kelly, Djuretic, Ivana M, Carlson, Thaddeus J, Quintero, Maria A, McCauley, Jacob L, Abreu, Maria T, Unutmaz, Derya, Sundrud, Mark S

“…IL-17A-expressing CD4(+) T cells (Th17 cells) are generally regarded as key effectors of autoimmune inflammation. However, not all Th17 cells are…”
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TLR Signaling in the Gut in Health and Disease by Abreu, Maria T, Fukata, Masayuki, Arditi, Moshe

“…The human intestine has evolved in the presence of diverse enteric microflora. TLRs convert the recognition of pathogen-associated molecules in the gut into…”
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Toll-like receptors (TLRs) and Nod-like receptors (NLRs) in inflammatory disorders by Fukata, Masayuki, Vamadevan, Arunan S, Abreu, Maria T

“…Abstract Toll-like receptors (TLRs) and Nod-like receptors (NLRs) are two major forms of innate immune sensors, which provide immediate responses against…”
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American Gastroenterological Association Institute Technical Review on Corticosteroids, Immunomodulators, and Infliximab in Inflammatory Bowel Disease by Lichtenstein, Gary R., Abreu, Maria T., Cohen, Russell, Tremaine, William

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Intestinal Epithelial Toll-Like Receptor 4 Signaling Affects Epithelial Function and Colonic Microbiota and Promotes a Risk for Transmissible Colitis by Dheer, Rishu, Santaolalla, Rebeca, Davies, Julie M, Lang, Jessica K, Phillips, Matthew C, Pastorini, Cristhine, Vazquez-Pertejo, Maria T, Abreu, Maria T

“…Evidence obtained from gene knockout studies supports the role of Toll-like receptor 4 (TLR4) in intestinal inflammation and microbiota recognition. Increased…”
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Antibiotic Therapy in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis by KHAN, Khurram J, ULLMAN, Thomas A, FORD, Alexander C, ABREU, Maria T, ABADIR, A, MARSHALL, John K, TALLEY, Nicholas J, MOAYYEDI, Paul

“…The etiology of inflammatory bowel disease (IBD) is unknown but may relate to an unidentified bacterial pathogen or an immunological reaction to gut…”
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Role of Toll-like receptors in gastrointestinal malignancies by Fukata, M, Abreu, M T

“…Mounting evidence supports the tenet that innate immune responses to luminal microbes participate in the development of gastrointestinal malignancies. The…”
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Reliability and Initial Validation of the Ulcerative Colitis Endoscopic Index of Severity by Travis, Simon P.L, Schnell, Dan, Krzeski, Piotr, Abreu, Maria T, Altman, Douglas G, Colombel, Jean–Frédéric, Feagan, Brian G, Hanauer, Stephen B, Lichtenstein, Gary R, Marteau, Philippe R, Reinisch, Walter, Sands, Bruce E, Yacyshyn, Bruce R, Schnell, Patrick, Bernhardt, Christian A, Mary, Jean–Yves, Sandborn, William J

“…Background & Aims We studied the reliability of the previously described Ulcerative Colitis Endoscopic Index of Severity (UCEIS) and validated it with an…”
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Effect of Increased Lactate Dehydrogenase A Activity and Aerobic Glycolysis on the Proinflammatory Profile of Autoimmune CD8+ T Cells in Rheumatoid Arthritis by Souto‐Carneiro, M. Margarida, Klika, Karel D., Abreu, Mónica T., Meyer, André P., Saffrich, Rainer, Sandhoff, Roger, Jennemann, Richard, Kraus, Franziska V., Tykocinski, Lars, Eckstein, Volker, Carvalho, Lina, Kriegsmann, Mark, Giese, Thomas, Lorenz, Hanns‐Martin, Carvalho, Rui A.

“…Objective CD8+ T cells contribute to rheumatoid arthritis (RA) by releasing proinflammatory and cytolytic mediators, even in a challenging hypoxic and…”
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Glucocorticosteroid Therapy in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis by FORD, Alexander C, BERNSTEIN, Charles N, KHAN, Khurram J, ABREU, Maria T, MARSHALL, John K, TALLEY, Nicholas J, MOAYYEDI, Paul

“…The use of glucocorticosteroids to treat both Crohn's disease (CD) and ulcerative colitis (UC) is widespread, but no systematic review and meta-analysis has…”
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