Search Results - "ABRAMS, Julian A"

Proton pump inhibitors alter the composition of the gut microbiota by Jackson, Matthew A, Goodrich, Julia K, Maxan, Maria-Emanuela, Freedberg, Daniel E, Abrams, Julian A, Poole, Angela C, Sutter, Jessica L, Welter, Daphne, Ley, Ruth E, Bell, Jordana T, Spector, Tim D, Steves, Claire J

“…Proton pump inhibitors (PPIs) are drugs used to suppress gastric acid production and treat GI disorders such as peptic ulcers and gastro-oesophageal reflux…”
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Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial by Freedberg, Daniel E, Toussaint, Nora C, Chen, Sway P, Ratner, Adam J, Whittier, Susan, Wang, Timothy C, Wang, Harris H, Abrams, Julian A

“…We conducted an open-label crossover trial to test whether proton pump inhibitors (PPIs) affect the gastrointestinal microbiome to facilitate Clostridium…”
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Epidemiology of Barrett’s Esophagus and Esophageal Adenocarcinoma by Runge, Thomas M., MD, MPH, Abrams, Julian A., MD, MS, Shaheen, Nicholas J., MD, MPH

“…Barrett’s esophagus (BE) is the precursor to esophageal adenocarcinoma (EAC), a disease with increasing burden in the Western world, especially in white men…”
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Proton pump inhibitors and risk for recurrent Clostridium difficile infection among inpatients by Freedberg, Daniel E, Salmasian, Hojjat, Friedman, Carol, Abrams, Julian A

“…Observational studies suggest that proton pump inhibitors (PPIs) are a risk factor for incident Clostridium difficile infection (CDI). Data also suggest an…”
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Elevated Preoperative Neutrophil:Lymphocyte Ratio as a Predictor of Postoperative Disease Recurrence in Esophageal Cancer by Sharaiha, Reem Z., Halazun, Karim J., Mirza, Farooq, Port, Jeffrey L., Lee, Paul C., Neugut, Alfred I., Altorki, Nasser K., Abrams, Julian A.

“…Background The prognosis for patients with esophageal cancer is poor, even among those who undergo potentially curative esophagectomy. The…”
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Bile Acid and Inflammation Activate Gastric Cardia Stem Cells in a Mouse Model of Barrett-Like Metaplasia by Quante, Michael, Bhagat, Govind, Abrams, Julian A., Marache, Frederic, Good, Pamela, Lee, Michele D., Lee, Yoomi, Friedman, Richard, Asfaha, Samuel, Dubeykovskaya, Zinaida, Mahmood, Umar, Figueiredo, Jose-Luiz, Kitajewski, Jan, Shawber, Carrie, Lightdale, Charles J., Rustgi, Anil K., Wang, Timothy C.

“…Esophageal adenocarcinoma (EAC) arises from Barrett esophagus (BE), intestinal-like columnar metaplasia linked to reflux esophagitis. In a transgenic mouse…”
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Biomarkers for oralization during long-term proton pump inhibitor therapy predict survival in cirrhosis by Horvath, Angela, Rainer, Florian, Bashir, Mina, Leber, Bettina, Schmerboeck, Bianca, Klymiuk, Ingeborg, Groselj-Strele, Andrea, Durdevic, Marija, Freedberg, Daniel E., Abrams, Julian A., Fickert, Peter, Stiegler, Philipp, Stadlbauer, Vanessa

“…Proton pump inhibitors (PPI) are an invaluable therapy option for acid related diseases; however, PPI therapy is also linked to a series of side effects in…”
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Real-time increased detection of neoplastic tissue in Barrett's esophagus with probe-based confocal laser endomicroscopy: final results of an international multicenter, prospective, randomized, controlled trial by Sharma, Prateek, MD, Meining, Alexander R., MD, PhD, Coron, Emmanuel, MD, Lightdale, Charles J., MD, Wolfsen, Herbert C., MD, Bansal, Ajay, MD, Bajbouj, Monther, MD, Galmiche, Jean-Paul, MD, Abrams, Julian A., MD, Rastogi, Amit, MD, Gupta, Neil, MD, MPH, Michalek, Joel E., PhD, Lauwers, Gregory Y., MD, Wallace, Michael B., MD, MPH

“…Background Probe-based confocal laser endomicroscopy (pCLE) allows real-time detection of neoplastic Barrett's esophagus (BE) tissue. However, the accuracy of…”
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Rapid gastrointestinal loss of Clostridial Clusters IV and XIVa in the ICU associates with an expansion of gut pathogens by Livanos, Alexandra E, Snider, Erik J, Whittier, Susan, Chong, David H, Wang, Timothy C, Abrams, Julian A, Freedberg, Daniel E

“…Commensal gastrointestinal bacteria resist the expansion of pathogens and are lost during critical illness, facilitating pathogen colonization and infection…”
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The Impact of Proton Pump Inhibitors on the Human Gastrointestinal Microbiome by Freedberg, Daniel E., MD, MS, Lebwohl, Benjamin, MD, MS, Abrams, Julian A., MD, MS

“…Potent gastric acid suppression using proton pump inhibitors (PPIs) is common in clinical practice but may have important effects on human health that are…”
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Prevalence of Extensive and Limited Gastric Intestinal Metaplasia and Progression to Dysplasia and Gastric Cancer by Laszkowska, Monika, Truong, Han, Faye, Adam S., Kim, Judith, Tan, Sarah Xinhui, Lim, Francesca, Abrams, Julian A., Hur, Chin

“…Background and Aims Guidelines cite extensive gastric intestinal metaplasia (GIM) as a bigger risk factor for gastric cancer (GC) than limited GIM and an…”
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Safety and efficacy of endoscopic spray cryotherapy for Barrett's esophagus with high-grade dysplasia by Shaheen, Nicholas J., MD, MPH, Greenwald, Bruce D., MD, Peery, Anne F., MD, Dumot, John A., MD, Nishioka, Norman S., MD, Wolfsen, Herbert C., MD, Burdick, J. Steven, MD, Abrams, Julian A., MD, Wang, Kenneth K., MD, Mallat, Damien, MD, Johnston, Mark H., MD, Zfass, Alvin M., MD, Smith, Jenny O., MD, Barthel, James S., MD, Lightdale, Charles J., MD

“…Background Endoscopic ablation to treat Barrett's esophagus (BE) with high-grade dysplasia (HGD) is associated with a decreased incidence of esophageal…”
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The effect of short-course antibiotics on the resistance profile of colonizing gut bacteria in the ICU: a prospective cohort study by Munck, Christian, Sheth, Ravi U, Cuaresma, Edward, Weidler, Jessica, Stump, Stephania L, Zachariah, Philip, Chong, David H, Uhlemann, Anne-Catrin, Abrams, Julian A, Wang, Harris H, Freedberg, Daniel E

“…The need for early antibiotics in the intensive care unit (ICU) is often balanced against the goal of antibiotic stewardship. Long-course antibiotics increase…”
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Dating the Rise of Esophageal Adenocarcinoma: Analysis of Connecticut Tumor Registry Data, 1940-2007 by ABRAMS, Julian A, SHARAIHA, Reem Z, GONSALVES, Lou, LIGHTDALE, Charles J, NEUGUT, Alfred I

“…The timing of onset of the rise in incidence of esophageal adenocarcinoma (EAC) has not been clearly defined, and doing so may provide clues with regard to…”
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Oral Microbiome Alterations and SARS-CoV-2 Saliva Viral Load in Patients with COVID-19 by Miller, Emily Happy, Annavajhala, Medini K, Chong, Alexander M, Park, Heekuk, Nobel, Yael R, Soroush, Ali, Blackett, John W, Krigel, Anna, Phipps, Meaghan M, Freedberg, Daniel E, Zucker, Jason, Sano, Ellen D, Uhlemann, Anne-Catrin, Abrams, Julian A

“…Bacterial-viral interactions in saliva have been associated with morbidity and mortality for respiratory viruses such as influenza and SARS-CoV. However, such…”
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Racial and Ethnic Disparities in the Prevalence of Barrett’s Esophagus Among Patients Who Undergo Upper Endoscopy by Abrams, Julian A, Fields, Sydney, Lightdale, Charles J, Neugut, Alfred I

“…Background & Aims: The incidence of esophageal adenocarcinoma (EAC) in blacks and Hispanics is well-described, but racial differences in the risk of Barrett’s…”
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Diverging Trends in the Incidence of Reflux-related and Helicobacter pylori-related Gastric Cardia Cancer by Abrams, Julian A, Gonsalves, Lou, Neugut, Alfred I

“…GOALS:To describe historical incidence trends of 2 subtypes of gastric cardia cancer. BACKGROUND:The incidence of gastric cardia cancer has increased in…”
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Folic Acid Increases Global DNA Methylation and Reduces Inflammation to Prevent Helicobacter-Associated Gastric Cancer in Mice by Gonda, Tamas A, Kim, Young–In, Salas, Martha C, Gamble, Mary V, Shibata, Wataru, Muthupalani, Sureshkumar, Sohn, Kyoung–Jin, Abrams, Julian A, Fox, James G, Wang, Timothy C, Tycko, Benjamin

“…Background & Aims Previous studies have suggested that dietary folic acid (FA) can protect against certain types of cancers. However, the findings have varied,…”
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Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett's-like esophagus by Lee, Yoomi, Urbanska, Aleksandra M, Hayakawa, Yoku, Wang, Hongshan, Au, Andrew S, Luna, Aesis M, Chang, Wenju, Jin, Guangchun, Bhagat, Govind, Abrams, Julian A, Friedman, Richard A, Varro, Andrea, Wang, Kenneth K, Boyce, Malcolm, Rustgi, Anil K, Sepulveda, Antonia R, Quante, Michael, Wang, Timothy C

“…The incidence of esophageal adenocarcinoma (EAC) is increasing, but factors contributing to malignant progression of its precursor lesion, Barrett's esophagus…”
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Shedding Light on the Value of Advanced Imaging in Barrett’s Esophagus by Abrams, Julian A., MD, MS

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