Search Results - "ABRAHAMS, L"
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Cell surface protein glycosylation in cancer
Published in Proteomics (Weinheim) (01-03-2014)“…Glycosylation of proteins is one of the most important PTMs, with more than half of all human proteins estimated to be glycosylated. It is widely known that…”
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Recent advances in glycoinformatic platforms for glycomics and glycoproteomics
Published in Current opinion in structural biology (01-06-2020)“…•Recent advancements in glycoinformatics tools to support analysis of glycan and glycopeptide data sets are summarised.•Review summarises the growth of machine…”
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3
Building a PGC-LC-MS N-glycan retention library and elution mapping resource
Published in Glycoconjugate journal (01-02-2018)“…Porous graphitised carbon-liquid chromatography (PGC-LC) has been proven to be a powerful technique for the analysis and characterisation of complex mixtures…”
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4
GlycoStore: a database of retention properties for glycan analysis
Published in Bioinformatics (15-09-2018)“…Abstract Summary GlycoStore is a curated chromatographic, electrophoretic and mass-spectrometry composition database of N-, O-, glycosphingolipid (GSL) glycans…”
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Fragmentation and ion mobility properties of negative ions from N-linked carbohydrates: Part 7. Reduced glycans
Published in Rapid communications in mass spectrometry (15-03-2016)“…Rationale Negative ion collision‐induced dissociation (CID) spectra of released N‐glycans provide very informative structural information relating to branching…”
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Integrated Glycoproteomics Identifies a Role of N-Glycosylation and Galectin-1 on Myogenesis and Muscle Development
Published in Molecular & cellular proteomics (2021)“…Many cell surface and secreted proteins are modified by the covalent addition of glycans that play an important role in the development of multicellular…”
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Method for milk oligosaccharide profiling by 2-aminobenzamide labeling and hydrophilic interaction chromatography
Published in Glycobiology (Oxford) (01-10-2011)“…Although the properties of milk oligosaccharides have been of scientific interest for many years, their structural diversity presents a challenging analytical…”
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The minimum information required for a glycomics experiment (MIRAGE) project: LC guidelines
Published in Glycobiology (Oxford) (01-05-2019)“…Abstract The Minimum Information Required for a Glycomics Experiment (MIRAGE) is an initiative created by experts in the fields of glycobiology, glycoanalytics…”
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Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation
Published in PLoS genetics (23-12-2010)“…Over half of all proteins are glycosylated, and alterations in glycosylation have been observed in numerous physiological and pathological processes. Attached…”
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10
N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease
Published in BMC cancer (26-03-2022)“…Normal human tissues do not express glycans terminating with the sialic acid N-glycolylneuraminic acid (Neu5Gc), yet Neu5Gc-containing glycans have been…”
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Glycosylation status of serum in inflammatory arthritis in response to anti-TNF treatment
Published in Rheumatology (Oxford, England) (01-09-2013)“…Glycosylation is the most common post-translational modification and is altered in disease. The typical glycosylation change in patients with inflammatory…”
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Essential roles for imuA' - and imuB -encoded accessory factors in DnaE2-dependent mutagenesis in Mycobacterium tuberculosis
Published in Proceedings of the National Academy of Sciences - PNAS (20-07-2010)“…In Mycobacterium tuberculosis (Mtb), damage-induced mutagenesis is dependent on the C-family DNA polymerase, DnaE2. Included with dnaE2 in the Mtb SOS regulon…”
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VapC toxins from Mycobacterium tuberculosis are ribonucleases that differentially inhibit growth and are neutralized by cognate VapB antitoxins
Published in PloS one (29-06-2011)“…The chromosome of Mycobacterium tuberculosis (Mtb) encodes forty seven toxin-antitoxin modules belonging to the VapBC family. The role of these modules in the…”
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Comprehensive analysis of the N-glycan biosynthetic pathway using bioinformatics to generate UniCorn: A theoretical N-glycan structure database
Published in Carbohydrate research (05-08-2016)“…Glycan structures attached to proteins are comprised of diverse monosaccharide sequences and linkages that are produced from precursor nucleotide-sugars by a…”
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15
Databases and Associated Tools for Glycomics and Glycoproteomics
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2017)“…The access to biodatabases for glycomics and glycoproteomics has proven to be essential for current glycobiological research. This chapter presents available…”
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GlycoDigest: a tool for the targeted use of exoglycosidase digestions in glycan structure determination
Published in Bioinformatics (Oxford, England) (01-11-2014)“…Sequencing oligosaccharides by exoglycosidases, either sequentially or in an array format, is a powerful tool to unambiguously determine the structure of…”
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17
Manipulating cellular transport and immune responses: dynamic interactions between intracellular Salmonella enterica and its host cells
Published in Cellular microbiology (01-05-2006)“…Summary Intracellular survival and replication within eukaryotic host cells is of central importance for the pathogenesis of infections caused by Salmonella…”
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Intracellular Salmonella enterica Redirect Exocytic Transport Processes in a Salmonella Pathogenicity Island 2‐Dependent Manner
Published in Traffic (Copenhagen, Denmark) (01-06-2006)“…During intracellular life, Salmonella enterica proliferate within a specialized membrane compartment, the Salmonella‐containing vacuole (SCV), and interfere…”
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Levels of specific glycans significantly distinguish lymph node-positive from lymph node-negative breast cancer patients
Published in Glycobiology (Oxford) (01-10-2010)“…One of the most urgent requirements in breast cancer is the development of a blood-based test for early detection and prognosis. Previously published results…”
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Role of the DinB Homologs Rv1537 and Rv3056 in Mycobacterium tuberculosis
Published in Journal of Bacteriology (01-04-2010)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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