Search Results - "ABMAN, S. H"

Bronchopulmonary dysplasia: "a vascular hypothesis" by Abman, S H

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Novel use of riociguat in infants with severe pulmonary arterial hypertension unable to wean from inhaled nitric oxide by Domingo, L T, Ivy, D D, Abman, S H, Grenolds, A M, MacLean, J T, Breaux, J A, Minford, K J, Frank, B S

“…Riociguat, an oral soluble guanylate cyclase stimulator, has been approved for use in adults with pulmonary arterial hypertension (PAH) and chronic…”
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Monitoring cardiovascular function in infants with chronic lung disease of prematurity by Abman, S H

“…In addition to persistent airways disease, survivors of premature birth with chronic lung disease are at risk of cardiovascular sequelae, including pulmonary…”
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Randomized, multicenter trial of inhaled nitric oxide and high-frequency oscillatory ventilation in severe, persistent pulmonary hypertension of the newborn by Kinsella, John P., Truog, William E., Walsh, William F., Goldberg, Ronald N., Bancalari, Eduardo, Mayock, Dennis E., Redding, Gregory J., deLemos, Robert A., Sardesai, Smeeta, McCurnin, Donald C., Moreland, Susan G., Cutter, Gary R., Abman, Steven H.

“…Background: Although inhaled nitric oxide (iNO) causes selective pulmonary vasodilation and improves oxygenation in newborn infants with persistent pulmonary…”
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Role of endothelium-derived relaxing factor during transition of pulmonary circulation at birth by Abman, S H, Chatfield, B A, Hall, S L, McMurtry, I F

“…To examine the potential role of endothelium-derived relaxing factor (EDRF) in regulation of the perinatal pulmonary circulation, we studied the hemodynamic…”
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Inhaled nitric oxide in premature neonates with severe hypoxaemic respiratory failure: a randomised controlled trial by Kinsella, John P, Walsh, William F, Bose, Carl L, Gerstmann, Dale R, Labella, JJ, Sardesai, Smeeta, Walsh-Sukys, Michele C, McCaffrey, Martin J, Cornfield, David N, Bhutani, Vinod K, Cutter, Gary R, Baier, Monika, Abman, Steven H

“…Inhaled nitric oxide improves oxygenation and lessens the need for extracorporeal-membrane oxygenation in full-term neonates with hypoxaemic respiratory…”
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Dipyridamole attenuates rebound pulmonary hypertension after inhaled nitric oxide withdrawal in postoperative congenital heart disease by Ivy, D.Dunbar, Kinsella, John P., Ziegler, James W., Abman, Steven H.

“…Objective: Inhaled nitric oxide therapy causes selective and sustained pulmonary vasodilation in patients with pulmonary hypertension; however, attempts to…”
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Clinical approach to inhaled nitric oxide therapy in newborn with hypoxemia by Kinsella, John P., Abman, Steven H.

“…Inhaled NO improves oxygenation and decreases ECMO use in term newborns with PPHN. From the available information, a reasonable recommendation for a starting…”
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Chronic intrauterine pulmonary hypertension impairs endothelial nitric oxide synthase in the ovine fetus by Villamor, E, Le Cras, T D, Horan, M P, Halbower, A C, Tuder, R M, Abman, S H

“…Endothelial (e) nitric oxide synthase (NOS) activity modulates pulmonary vascular tone in the normal fetus and decreases pulmonary vascular resistance (PVR) at…”
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Multicenter randomized controlled trial of the effects of inhaled nitric oxide therapy on gas exchange in children with acute hypoxemic respiratory failure by Dobyns, Emily L., Cornfield, David N., Anas, Nick G., Fortenberry, James D., Tasker, Robert C., Lynch, Amy, Liu, Paul, Eells, Patricia L., Griebel, Jeff, Baier, Monika, Kinsella, John P., Abman, Steven H.

“…Objectives and background: To determine whether inhaled nitric oxide (iNO) therapy can attenuate the progression of lung disease in acute hypoxemic respiratory…”
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Effects of birth-related stimuli on L-arginine-dependent pulmonary vasodilation in ovine fetus by Cornfield, D N, Chatfield, B A, McQueston, J A, McMurtry, I F, Abman, S H

“…To determine the effects of birth-related stimuli on L-arginine-dependent vasodilation or nitric oxide (NO) activity in the perinatal lung, we studied the…”
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Recent developments in the pathophysiology and treatment of persistent pulmonary hypertension of the newborn by Kinsella, John P., Abman, Steven H.

“…Successful management of severe PPHN depends on the application of appropriate strategies to manage the cardiopulmonary interactions that characterize this…”
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Clinical responses to prolonged treatment of persistent pulmonary hypertension of the newborn with low doses of inhaled nitric oxide by Kinsella, J P, Neish, S R, Ivy, D D, Shaffer, E, Abman, S H

“…We studied the efficacy of low-dose nitric oxide inhalation in nine consecutive patients with severe persistent pulmonary hypertension of the newborn (PPHN)…”
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Physiologic characterization of endothelin A and B receptor activity in the ovine fetal pulmonary circulation by IVY, D. D, KINSELLA, J. P, ABMAN, S. H

“…To determine the potential contribution of endothelin (ET) to modulation of high pulmonary vascular resistance in the normal fetus, we studied the effects of…”
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Effects of inhaled nitric oxide on pulmonary edema and lung neutrophil accumulation in severe experimental hyaline membrane disease by KINSELLA, J. P, PARKER, T. A, GALAN, H, SHERIDAN, B. C, HALBOWER, A. C, ABMAN, S. H

“…To determine the effects of inhaled NO (iNO) on pulmonary edema and lung inflammation in experimental hyaline membrane disease (HMD), we measured the effects…”
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Acute hypoxia causes membrane depolarization and calcium influx in fetal pulmonary artery smooth muscle cells by Cornfield, D N, Stevens, T, McMurtry, I F, Abman, S H, Rodman, D M

“…Changes in oxygen tension in the perinatal period contribute to high pulmonary vascular tone in the fetus and the decline in resistance that occurs at birth…”
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Ontogeny of NO activity and response to inhaled NO in the developing ovine pulmonary circulation by Kinsella, J P, Ivy, D D, Abman, S H

“…To determine maturation-related changes in nitric oxide (NO) activity in the developing pulmonary circulation, we studied the hemodynamic effects of endogenous…”
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Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension by TUDER, R. M, COOL, C. D, GERACI, M. W, JUN WANG, ABMAN, S. H, WRIGHT, L, BADESCH, D, VOELKEL, N. F

“…Prostacyclin is a powerful vasodilator and inhibits platelet adhesion and cell growth. We hypothesized that a decrease in expression of the critical enzyme…”
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Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension by ZIEGLER, J. W, IVY, D. D, WIGGINS, J. W, KINSELLA, J. P, CLARKE, W. R, ABMAN, S. H

“…Inhaled nitric oxide (iNO) causes selective pulmonary vasodilation by increasing pulmonary vascular levels of cyclic guanosine monophosphate (cGMP)…”
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Inhaled nitric oxide in the management of a premature newborn with severe respiratory distress and pulmonary hypertension by ABMAN, S. H, KINSELLA, J. P, SCHAFFER, M. S, WILKENING, R. B

“…Persistent pulmonary hypertension of the newborn (PPHN) is a clinical syndrome, characterized by sustained elevation of pulmonary vascular resistance (PVR)…”
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