Search Results - "ABDOOL KARIM, S. S"
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The South African Response to the Pandemic
Published in The New England journal of medicine (11-06-2020)“…South Africa’s early interventions have delayed the peak of Covid-19 cases. The author describes the eight stages of the national response and ongoing…”
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HIV-1 Epidemic Control — Insights from Test-and-Treat Trials
Published in The New England journal of medicine (18-07-2019)“…Debate ensued when mathematical models 1 predicted that universal testing and treatment could achieve epidemic control within a few years in a high-burden…”
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Addressing Vaccine Inequity — Covid-19 Vaccines as a Global Public Good
Published in The New England journal of medicine (24-03-2022)“…The editors of the Journal note that although the rapid development of Covid-19 vaccines would appear to be a landmark success in global health mobilization,…”
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Time to Stop Using Ineffective Covid-19 Drugs
Published in The New England journal of medicine (18-08-2022)“…In practicing evidence-based medicine, physicians use the best evidence currently available on safety and efficacy in making decisions on treatment choices for…”
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Clinical Trials of Broadly Neutralizing Monoclonal Antibodies for Human Immunodeficiency Virus Prevention: A Review
Published in The Journal of infectious diseases (13-02-2021)“…Abstract Passive immunization with broadly neutralizing antibodies (bnAbs) is a promising approach to reduce the 1.7 million annual human immunodeficiency…”
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Clinical severity of COVID-19 in patients admitted to hospital during the omicron wave in South Africa: a retrospective observational study
Published in The Lancet global health (01-07-2022)“…Up to the end of January, 2022, South Africa has had four recognisable COVID-19 pandemic waves, each predominantly dominated by one variant of concern: the…”
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Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection
Published in Nature communications (10-08-2022)“…SARS-CoV-2 Omicron (B.1.1.529) BA.4 and BA.5 sub-lineages, first detected in South Africa, have changes relative to Omicron BA.1 including substitutions in the…”
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Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic
Published in The Lancet (British edition) (11-12-2021)Get full text
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Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women
Published in Science (American Association for the Advancement of Science) (02-06-2017)“…Antiretroviral-based strategies for HIV prevention have shown inconsistent results in women. We investigated whether vaginal microbiota modulated tenofovir gel…”
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New SARS-CoV-2 Variants — Clinical, Public Health, and Vaccine Implications
Published in The New England journal of medicine (13-05-2021)“…The emergence of the SARS-CoV-2 variants B.1.1.7 (VOC-202012/01), 501Y.V2 (B.1.351), and P.1 (B.1.1.28.1) has aroused many concerns, including worsening…”
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HIV infection and tuberculosis in South Africa: an urgent need to escalate the public health response
Published in The Lancet (British edition) (12-09-2009)“…Summary One of the greatest challenges facing post-apartheid South Africa is the control of the concomitant HIV and tuberculosis epidemics. HIV continues to…”
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Health in South Africa: changes and challenges since 2009
Published in The Lancet (British edition) (08-12-2012)“…Summary Since the 2009 Lancet Health in South Africa Series, important changes have occurred in the country, resulting in an increase in life expectancy to 60…”
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13
Genital Inflammation and the Risk of HIV Acquisition in Women
Published in Clinical infectious diseases (15-07-2015)“…Background. Women in Africa, especially young women, have very high human immunodeficiency virus (HIV) incidence rates that cannot be fully explained by…”
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Appropriate names for COVID-19 variants
Published in Science (American Association for the Advancement of Science) (19-03-2021)Get full text
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Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes
Published in PLoS pathogens (01-10-2013)“…Identifying the targets of broadly neutralizing antibodies to HIV-1 and understanding how these antibodies develop remain important goals in the quest to…”
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COVID-19 in Africa: Catalyzing change for sustainable development
Published in PLoS medicine (29-11-2021)“…Salim Abdool Karim, Segenet Kelemu and Cheryl Baxter discuss COVID-19 impacts and adaptations in Africa…”
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Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
Published in Science (American Association for the Advancement of Science) (03-09-2010)“…The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed the effectiveness and safety of a 1% vaginal gel formulation of…”
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Defeating AIDS—advancing global health
Published in The Lancet (British edition) (11-07-2015)“…Thanks to considerable resources, leadership, community mobilisation, and innovation, enormous gains have been made in controlling the HIV epidemic, saving…”
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Criminalisation of transmission of SARS-CoV-2: A potential challenge to controlling the outbreak in South Africa
Published in South African medical journal (22-04-2020)“…In March 2020, two cases of attempted murder were opened against people who had tested positive for COVID-19 and had not remained in quarantine. Criminal law…”
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Integration of Antiretroviral Therapy with Tuberculosis Treatment
Published in The New England journal of medicine (20-10-2011)“…In this study from South Africa, earlier initiation of antiretroviral therapy in patients with newly diagnosed HIV infection and TB was associated with higher…”
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