Search Results - "ABBOUD, Camille N"
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Selinexor combined with cladribine, cytarabine, and filgrastim in relapsed or refractory acute myeloid leukemia
Published in Haematologica (Roma) (01-08-2020)Get full text
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Control of Plasma Uric Acid in Adults at Risk for Tumor Lysis Syndrome: Efficacy and Safety of Rasburicase Alone and Rasburicase Followed by Allopurinol Compared With Allopurinol Alone—Results of a Multicenter Phase III Study
Published in Journal of clinical oncology (20-09-2010)“…Rasburicase is effective in controlling plasma uric acid in pediatric patients with hematologic malignancies. This study in adults evaluated safety of and…”
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Decitabine salvage for TP53 -mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy
Published in Haematologica (Roma) (01-07-2022)Get full text
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Leukostasis in adult acute hyperleukocytic leukemia: a clinician's digest
Published in Hematological oncology (01-06-2016)“…Leukostasis is a poorly understood and life‐threatening complication of acute hyperleukocytic leukemia. The incidence of hyperleukocytosis and leukostasis…”
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Serendipity: decitabine monotherapy induced complete molecular response in a 77-year-old patient with acute promyelocytic leukemia
Published in Haematologica (Roma) (01-04-2019)Get full text
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Phase I study of cladribine, cytarabine, granulocyte colony stimulating factor (CLAG regimen) and midostaurin and all-trans retinoic acid in relapsed/refractory AML
Published in International journal of hematology (01-03-2014)“…We conducted a phase I study using midostaurin (25 or 50 mg orally twice daily), all- trans retinoic acid (ATRA) and CLAG chemotherapy to target multiple…”
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A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia
Published in Blood (26-04-2012)“…The interaction of acute myeloid leukemia (AML) blasts with the leukemic microenvironment is postulated to be an important mediator of resistance to…”
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Systemic IL-15 promotes allogeneic cell rejection in patients treated with natural killer cell adoptive therapy
Published in Blood (24-02-2022)“…Natural killer (NK) cells are a promising alternative to T cells for cancer immunotherapy. Adoptive therapies with allogeneic, cytokine-activated NK cells are…”
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Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia
Published in Science translational medicine (23-02-2022)“…Natural killer (NK) cells are innate lymphoid cells that eliminate cancer cells, produce cytokines, and are being investigated as a nascent cellular…”
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Impact of Mobilization and Remobilization Strategies on Achieving Sufficient Stem Cell Yields for Autologous Transplantation
Published in Biology of blood and marrow transplantation (01-09-2008)“…Abstract The purpose of this article was to examine historic institutional autologous stem cell mobilization practices and evaluate factors influencing…”
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Mobilization of allogeneic peripheral blood stem cell donors with intravenous plerixafor mobilizes a unique graft
Published in Blood (11-05-2017)“…A single subcutaneous (SC) injection of plerixafor results in rapid mobilization of hematopoietic progenitors, but fails to mobilize 33% of normal allogeneic…”
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Protective Effect of Cytomegalovirus Reactivation on Relapse after Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid Leukemia Patients Is Influenced by Conditioning Regimen
Published in Biology of blood and marrow transplantation (2014)“…Abstract Cytomegalovirus (CMV) reactivation after allogeneic hematopoietic cell transplant (allo-HCT) has been associated with a reduced risk of relapse in…”
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Monitoring clonal burden as an alternative to blast count for myelodysplastic neoplasm treatment response
Published in Leukemia (04-10-2024)“…Accurate assessment of therapy response in myelodysplastic neoplasm (MDS) has been challenging. Directly monitoring mutational disease burden may be useful,…”
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Polycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery of JAK2 V617F
Published in Journal of clinical oncology (20-11-2015)“…Polycythemia vera (PV) is a chronic myeloproliferative neoplasm that is associated with a substantial symptom burden, thrombohemorrhagic complications, and…”
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Rapid Method for Detection of Mutations in the Nucleophosmin Gene in Acute Myeloid Leukemia
Published in The Journal of molecular diagnostics : JMD (01-07-2008)“…Mutations in exon 12 of the nucleophosmin gene ( NPM1 ) that cause the encoded protein to abnormally relocate to the cytoplasm are found at diagnosis in about…”
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Open-Label Phase II Prospective, Randomized, Controlled Study of Romyelocel-L Myeloid Progenitor Cells to Reduce Infection During Induction Chemotherapy for Acute Myeloid Leukemia
Published in Journal of clinical oncology (10-10-2021)“…Standard cytotoxic induction chemotherapy for acute myeloid leukemia (AML) results in prolonged neutropenia and risk of infection. Romyelocel-L is a universal,…”
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Real-world safety experience of tevagrastim/ratiograstim/biograstim and tbo-filgrastim, short-acting recombinant human granulocyte colony-stimulating factors
Published in Supportive care in cancer (01-07-2019)“…Purpose Recombinant granulocyte colony-stimulating factors (rG-CSFs), such as filgrastim, are administered to prevent complications in patients receiving…”
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A phase 2 study of high-dose lenalidomide as initial therapy for older patients with acute myeloid leukemia
Published in Blood (10-02-2011)“…Older patients with acute myeloid leukemia (AML) have limited treatment options and a poor prognosis, thereby warranting novel therapeutic strategies. We…”
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ASCT2-Targeting Antibody-Drug Conjugate MEDI7247 in Adult Patients with Relapsed/Refractory Hematological Malignancies: A First-in-Human, Phase 1 Study
Published in Targeted oncology (01-05-2024)“…Background MEDI7247 is a first-in-class antibody-drug conjugate (ADC) consisting of an anti-sodium-dependent alanine-serine-cysteine transporter 2…”
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