Search Results - "ABADIE, Eric"

Variation in Health Technology Assessment and Reimbursement Processes in Europe by Akehurst, Ronald L, BSc, DSc, Abadie, Eric, MD, MBA, Renaudin, Noël, Sarkozy, François, MD

“…Abstract Background It has been suggested that differences in health technology assessment (HTA) processes among countries, particularly within Europe, have…”
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Two decades of oligotrophication: Evidence for a phytoplankton community shift in the coastal lagoon of Thau (Mediterranean Sea, France) by Derolez, Valérie, Soudant, Dominique, Malet, Nathalie, Chiantella, Claude, Richard, Marion, Abadie, Eric, Aliaume, Catherine, Bec, Béatrice

“…Mediterranean costal lagoons have been exposed to anthropic eutrophication for decades. Thau lagoon is one of the largest among them and provides many…”
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Open clinical trial data for all? A view from regulators by Eichler, Hans-Georg, Abadie, Eric, Breckenridge, Alasdair, Leufkens, Hubert, Rasi, Guido

“…First among those is the issue of personal data protection or patient confidentiality, a concept that is very different from commercial confidentiality…”
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Chemodiversity of Brevetoxins and Other Potentially Toxic Metabolites Produced by Karenia spp. and Their Metabolic Products in Marine Organisms by Hort, Vincent, Abadie, Eric, Arnich, Nathalie, Dechraoui Bottein, Marie-Yasmine, Amzil, Zouher

“…In recent decades, more than 130 potentially toxic metabolites originating from dinoflagellate species belonging to the genus or metabolized by marine…”
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Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium by Dieterle, Frank, Sistare, Frank, Goodsaid, Federico, Papaluca, Marisa, Ozer, Josef S, Webb, Craig P, Baer, William, Senagore, Anthony, Schipper, Matthew J, Vonderscher, Jacky, Sultana, Stefan, Gerhold, David L, Phillips, Jonathan A, Maurer, Gérard, Carl, Kevin, Laurie, David, Harpur, Ernie, Sonee, Manisha, Ennulat, Daniela, Holder, Dan, Andrews-Cleavenger, Dina, Gu, Yi-Zhong, Thompson, Karol L, Goering, Peter L, Vidal, Jean-Marc, Abadie, Eric, Maciulaitis, Romaldas, Jacobson-Kram, David, Defelice, Albert F, Hausner, Elizabeth A, Blank, Melanie, Thompson, Aliza, Harlow, Patricia, Throckmorton, Douglas, Xiao, Shen, Xu, Nancy, Taylor, William, Vamvakas, Spiros, Flamion, Bruno, Lima, Beatriz Silva, Kasper, Peter, Pasanen, Markku, Prasad, Krishna, Troth, Sean, Bounous, Denise, Robinson-Gravatt, Denise, Betton, Graham, Davis, Myrtle A, Akunda, Jackie, McDuffie, James Eric, Suter, Laura, Obert, Leslie, Guffroy, Magalie, Pinches, Mark, Jayadev, Supriya, Blomme, Eric A, Beushausen, Sven A, Barlow, Valérie G, Collins, Nathaniel, Waring, Jeff, Honor, David, Snook, Sandra, Lee, Jinhe, Rossi, Phil, Walker, Elizabeth, Mattes, William

“…The first formal qualification of safety biomarkers for regulatory decision making marks a milestone in the application of biomarkers to drug development…”
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Dietary BMAA exposure in an amyotrophic lateral sclerosis cluster from southern France by Masseret, Estelle, Banack, Sandra, Boumédiène, Farid, Abadie, Eric, Brient, Luc, Pernet, Fabrice, Juntas-Morales, Raoul, Pageot, Nicolas, Metcalf, James, Cox, Paul, Camu, William

“…Dietary exposure to the cyanotoxin BMAA is suspected to be the cause of amyotrophic lateral sclerosis in the Western Pacific Islands. In Europe and North…”
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Guidance Level for Brevetoxins in French Shellfish by Arnich, Nathalie, Abadie, Eric, Amzil, Zouher, Dechraoui Bottein, Marie-Yasmine, Comte, Katia, Chaix, Estelle, Delcourt, Nicolas, Hort, Vincent, Mattei, César, Molgó, Jordi, Le Garrec, Raphaele

“…Brevetoxins (BTXs) are marine biotoxins responsible for neurotoxic shellfish poisoning (NSP) after ingestion of contaminated shellfish. NSP is characterized by…”
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Human shellfish poisoning: Implementation of a national surveillance program in France by Sinno-Tellier, Sandra, Abadie, Eric, Guillotin, Sophie, Bossée, Anne, Nicolas, Marina, Delcourt, Nicolas

“…Toxic algae and their toxins represent an emerging public health issue, particularly due to global warming. The toxicological mechanisms of neurotoxic…”
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Relative efficacy of drugs: an emerging issue between regulatory agencies and third-party payers by Bloechl-Daum, Brigitte, Eichler, Hans-Georg, Abadie, Eric, Barnett, David, König, Franz, Pearson, Steven

“…Third-party payers typically base their reimbursement decisions for a new drug predominantly on its health benefits relative to existing treatment options —…”
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Artificial Substrates Coupled with qPCR (AS-qPCR) Assay for the Detection of the Toxic Benthopelagic Dinoflagellate Vulcanodinium rugosum by Bouquet, Aurélien, Felix, Christine, Masseret, Estelle, Reymond, Coralie, Abadie, Eric, Laabir, Mohamed, Rolland, Jean Luc

“…is an emerging benthopelagic neuro-toxic dinoflagellate species responsible for seasonal Pinnatoxins and Portimines contaminations of shellfish and marine…”
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Beta-N-methylamino-L-alanine: LC-MS/MS optimization, screening of cyanobacterial strains and occurrence in shellfish from Thau, a French Mediterranean lagoon by Réveillon, Damien, Abadie, Eric, Séchet, Véronique, Brient, Luc, Savar, Véronique, Bardouil, Michèle, Hess, Philipp, Amzil, Zouher

“…β-N-methylamino-L-alanine (BMAA) is a neurotoxic non-protein amino acid suggested to be involved in neurodegenerative diseases. It was reported to be produced…”
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Liza ramada Juveniles after Exposure to the Toxic Dinoflagellate Vulcanodinium rugosum: Effects on Fish Viability, Tissue Contamination and Microalgae Survival after Gut Passage by Bouquet, Aurélien, Perdrau, Marie Anaïs, Laabir, Mohamed, Foucault, Elodie, Chomérat, Nicolas, Rolland, Jean Luc, Abadie, Eric

“…Pinnatoxins (PnTX) and Portimines (Prtn), two toxins produced by the benthic dinoflagellate Vulcanodinium rugosum, are known to be lethal to mice after…”
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A regulatory Apologia — A review of placebo-controlled studies in regulatory submissions of new-generation antidepressants by Melander, Hans, Salmonson, Tomas, Abadie, Eric, van Zwieten-Boot, Barbara

“…Abstract Data on percentage of patients experiencing a relevant response (> 50% reduction of the baseline Hamilton Depression Scale (HAMD) score), average…”
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Influence of environmental factors on the paralytic shellfish toxin content and profile of Alexandrium catenella (Dinophyceae) isolated from the Mediterranean Sea by Laabir, Mohamed, Collos, Yves, Masseret, Estelle, Grzebyk, Daniel, Abadie, Eric, Savart, Véronique, Sibat, Manoella, Amzil, Zouher

“…Laboratory experiments were designed to study the toxin content and profile of the Alexandrium catenella strain ACT03 (isolated from Thau Lagoon, French…”
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Toxicity and Growth Assessments of Three Thermophilic Benthic Dinoflagellates (Ostreopsis cf. ovata, Prorocentrum lima and Coolia monotis) Developing in the Southern Mediterranean Basin by Ben-Gharbia, Hela, Yahia, Ons Kéfi-Daly, Amzil, Zouher, Chomérat, Nicolas, Abadie, Eric, Masseret, Estelle, Sibat, Manoella, Zmerli Triki, Habiba, Nouri, Habiba, Laabir, Mohamed

“…Harmful benthic dinoflagellates, usually developing in tropical areas, are expanding to temperate ecosystems facing water warming. Reports on harmful benthic…”
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Tetrodotoxins in French Bivalve Mollusks-Analytical Methodology, Environmental Dynamics and Screening of Bacterial Strain Collections by Réveillon, Damien, Savar, Véronique, Schaefer, Estelle, Chevé, Julien, Halm-Lemeille, Marie-Pierre, Hervio-Heath, Dominique, Travers, Marie-Agnès, Abadie, Eric, Rolland, Jean-Luc, Hess, Philipp

“…Tetrodotoxins (TTXs) are potentially lethal paralytic toxins that have been identified in European shellfish over recent years. Risk assessment has suggested…”
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Clinical trials of new drugs for the treatment of rheumatoid arthritis: focus on early disease by Smolen, Josef S, Collaud Basset, Sabine, Boers, Maarten, Breedveld, Ferdinand, Edwards, Christopher J, Kvien, Tore K, Miossec, Pierre, Sokka-Isler, Tuulikki, van Vollenhoven, Ronald F, Abadie, Eric C, Bruyère, Olivier, Cooper, Cyrus, Mäkinen, Heidi, Thomas, Thierry, Tugwell, Peter, Reginster, Jean-Yves

“…The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases convened a task force of experts in…”
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Pinnatoxins' Deleterious Effects on Cholinergic Networks: From Experimental Models to Human Health by Delcourt, Nicolas, Lagrange, Emmeline, Abadie, Eric, Fessard, Valérie, Frémy, Jean-Marc, Vernoux, Jean-Paul, Peyrat, Marie-Bénédicte, Maignien, Thomas, Arnich, Nathalie, Molgó, Jordi, Mattei, César

“…Pinnatoxins (PnTXs) are emerging neurotoxins that were discovered about 30 years ago. They are solely produced by the marine dinoflagellate , and may be…”
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Oyster Farming, Temperature, and Plankton Influence the Dynamics of Pathogenic Vibrios in the Thau Lagoon by Lopez-Joven, Carmen, Rolland, Jean-Luc, Haffner, Philippe, Caro, Audrey, Roques, Cécile, Carré, Claire, Travers, Marie-Agnès, Abadie, Eric, Laabir, Mohamed, Bonnet, Delphine, Destoumieux-Garzón, Delphine

“…species have been associated with recurrent mass mortalities of juvenile oysters threatening oyster farming worldwide. However, knowledge of the ecology of…”
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Oligotrophication and emergence of picocyanobacteria and a toxic dinoflagellate in Thau lagoon, southern France by Collos, Yves, Bec, Béatrice, Jauzein, Cécile, Abadie, Eric, Laugier, Thierry, Lautier, Jacques, Pastoureaud, Annie, Souchu, Philippe, Vaquer, André

“…Time series data have been examined in Thau lagoon (Southern France) from 1972 to 2006 for water temperature, salinity, nutrients and from 1987 to 2006 for…”
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