Search Results - "A.S. Perelson"

1196 ANALYSIS OF THE KINETICS OF VIRAL DECLINE DURING 14 DAYS OF ADMINISTRATION OF SOFOSBUVIR AND GS-0938 by Guedj, J, Pang, P.S, Lawitz, E, Rodriguez-Torres, M, Symonds, B, Perelson, A.S

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A theoretical framework to guide clinical trial design to estimate efficacies of latency-reversing agents by R. Ke, J.M. Conway, A.S. Perelson

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Constraints on the dynamics of HIV-1 lifecycle elucidated by treatment with an integrase inhibitor reveal a subset of cells with very slow integration by R.M. Ribeiro, F. Cardozo, A.S. Perelson

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1201 NEW INSIGHTS INTO THE MECHANISM OF ACTION OF INTERFERON-ALPHA AND BMS-790052: A MULTI-SCALE MATHEMATICAL MODELING APPROACH by Dahari, H, Guedj, J, Rong, L, Nettles, R.E, Cotler, S.J, Layden, T.J, Perelson, A.S

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Sustained HIV release by single persisting CD4+ T cells during latency disruption by J.M. Hataye, J.P. Casazza, D.R. Ambrozak, E. Boritz, T. Yamamoto, D.C. Douek, A.S. Perelson, R.A. Koup

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823 MODELING EARLY VIRAL KINETICS WITH ALISPORIVIR: INTERFERON-FREE TREATMENT AND SVR PREDICTIONS IN HCV G2/3 PATIENTS by Guedj, J, Yu, J, Levi, M, Kern, S, Naoumov, N.V, Perelson, A.S

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776 MODELING INTERFERON-ALPHA MEDIATED INHIBITION KINETICS OF INTRACELLULAR AND EXTRACELLULAR HCVRNA DURING HCV INFECTION IN VITRO by Dahari, H, Barretto, N, Sainz, B.J, Guedj, J, Perelson, A.S, Uprichard, S.L

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Immunology for physicists by Perelson, Alan S., Weisbuch, Gérard

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The complexity of complexes in signal transduction by Hlavacek, William S., Faeder, James R., Blinov, Michael L., Perelson, Alan S., Goldstein, Byron

“…Many activities of cells are controlled by cell‐surface receptors, which in response to ligands, trigger intracellular signaling reactions that elicit cellular…”
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HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time by Perelson, Alan S., Neumann, Avidan U., Markowitz, Martin, Leonard, John M., Ho, David D.

“…A new mathematical model was used to analyze a detailed set of human immunodeficiency virus-type 1 (HIV-1) viral load data collected from five infected…”
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Development of the T-Cell Repertoire: of Clone Size Distribution by Merrill, S.J., Deboer, R.J., Perelson, A.S.

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739 Mathematical modeling of subgenomic hepatitis C viral replication in HUH-7 cells by Dahari, H., Ribeiro, R.M., Rice, C.M., Perelson, A.S.

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Dynamics of HIV infection of CD4+ T cells by Perelson, A S, Kirschner, D E, De Boer, R

“…We examine a model for the interaction of HIV with CD4+ T cells that considers four populations: uninfected T cells, latently infected T cells, actively…”
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Target Cell Limited and Immune Control Models of HIV Infection: A Comparison by De Boer, R.J., Perelson, A.S.

“…We develop various mathematical models of the clinical latency stage of HIV-1 infection assuming that HIV-1 infection is limited either by the availability of…”
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Towards a general function describing t cell proliferation by De Boer, Rob J., Perelson, A.S.

“…A new function is proposed for describing the rate of T cell proliferation in response to peptides on antigen-presenting cells. The model improves an earlier…”
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Protein Evolution on Partially Correlated Landscapes by Perelson, Alan S., Macken, Catherine A.

“…We extend an earlier model of protein evolution on a rugged landscape to the case in which the landscape exhibits a variable degree of correlation (i.e.,…”
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Acute hepatitis C in patients receiving hemodialysis by Griveas, I, Germanidis, G, Visvardis, G, Morice, Y, Perelson, A S, Pawlotsky, J M, Papadopoulou, D

“…Hepatitis C virus (HCV) infection is frequent in patients with end-stage renal disease treated by chronic dialysis, with a prevalence varying from 10-65%…”
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Th1/Th2 Differentiation and Cross-regulation by Fishman, M.A., Perelson, A.S.

“…The T helper (Th) phenotypes, Th1/Th2, are acquired upon interaction of a naive T helper cell and an antigen presenting cell (APC). Naive T helper cells may…”
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Predicting the Size of the T-Cell Receptor and Antibody Combining Region from Consideration of Efficient Self-Nonself Discrimination by Percus, Jerome K., Percus, Ora E., Perelson, Alan S.

“…The binding of antibody to antigen or T-cell receptor to major histocompatibility complex-peptide complex requires that portions of the two structures have…”
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Protein Evolution on Rugged Landscapes by Macken, Catherine A., Perelson, Alan S.

“…We analyze a mathematical model of protein evolution in which the evolutionary process is viewed as hill-climbing on a random fitness landscape. In studying…”
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