Search Results - "A.A. Elkanzi, Nadia"
-
1
Design and cytotoxic activity of thiazolidinones via one-pot, three component reaction under microwave and traditional method
Published in Bulletin of the Chemical Society of Ethiopia (01-05-2024)“…Treatment of sulfamethoxazole (SMZ ) (1) with different aromatic aldehydes 2a-f within few minutes (5-8 min) afforded the corresponding Schiff bases 3a-f which…”
Get full text
Journal Article -
2
Three Co(II), Ni(II) and Cu(II) Schiff base complexes incorporating 2-[(4-{[(4-methylphenyl)sulfonothioyl]oxy}phenyl)methylene] amino}benzoic acid: Synthesis, structural, dft, biological and molecular docking investigation
Published in Bulletin of the Chemical Society of Ethiopia (01-01-2024)“…New 2-[(4-[(4-methylphenyl)sulfonothioyl)methylene]aminobenzoic acid ligand-Co(II), Ni(II), and Cu(II) complexes are synthesized and characterized in this…”
Get full text
Journal Article -
3
Design, Synthesis, and Antimicrobial Evaluation of New Annelated Pyrimido[2,1- c ][1,2,4]triazolo[3,4- f ][1,2,4]triazines
Published in Molecules (Basel, Switzerland) (15-03-2020)“…A series of 34 new pyrimido[2,1- ][1,2,4]triazine-3,4-diones were synthesized and fully characterized using IR, NMR, MS, and microanalytical analysis. In vitro…”
Get full text
Journal Article -
4
An Efficient Synthetic Approach Towards Benzo[ b ]pyrano[2,3- e ][1,4]diazepines, and Their Cytotoxic Activity
Published in Molecules (Basel, Switzerland) (28-04-2020)“…In search of unprecedented tri and/or tetrapod pharmacophoric conjugates, a series of 32 new 4-ethyl-1 -benzo[ ][1,4]diazepin-2(3 )-ones were synthesized and…”
Get full text
Journal Article -
5
Targeting tumor cells with pyrazolo[3,4-d]pyrimidine scaffold: A literature review on synthetic approaches, structure activity relationship, structural and target-based mechanisms
Published in Arabian journal of chemistry (01-05-2022)“…Pyrazolo[3,4-d]pyrimidine had been attracted awesome interest due to its pharmacological potential especially as an anticancer. Several mechanisms of action…”
Get full text
Journal Article -
6
Novel indan-1,3-dione derivatives: Design, green synthesis, effect against tomato damping-off disease caused by Fusarium oxysporum and in silico molecular docking study
Published in Arabian journal of chemistry (01-05-2022)“…[Display omitted] An effective method for synthesizing series of twenty-two new compounds 1, 2a,b, 3, 4a,b, 5a-e, 7, 8, 9, 10, 12, 13a-d, 15a,b was performed…”
Get full text
Journal Article -
7
Synthesis of some novel phenylfuro[3,2-d]pyrimidine glycosides derivatives with expected antimicrobial activity
Published in Journal of the Iranian Chemical Society (01-02-2020)“…Reaction of ethyl 3-amino-5-phenylfuran-2-carboxylate 1 with benzoyl isothiocyanate gave 2,3-dihydro-6-phenyl-2-thioxofuro[3,2- d ]pyrimidin-4-one. Compound 3…”
Get full text
Journal Article -
8
Synthesis, in vitro evaluation and molecular docking of new pyrazole derivatives bearing 1,5,10,10a-tetrahydrobenzo[g]quinoline-3-carbonitrile moiety as potent antibacterial agents
Published in Journal of the Iranian Chemical Society (01-04-2021)“…In the current study, a new series of pyrazole derivatives 4a – d , 5a – d and 6a – d possessing 1,5,10,10a-tetrahydrobenzo[ g ]quinoline-3-carbonitrile moiety…”
Get full text
Journal Article -
9
Nickel oxide nanoparticles as sustainable catalysts for efficient synthesis and anti-microbial evaluation of 2-amino-4H-pyran derivatives
Published in Bulletin of the Chemical Society of Ethiopia (01-01-2024)“…In the current paper, nickel oxide nanoparticles (NiO NPs) was successfully applied as a sustainable effective and recoverable catalyst for the preparation of…”
Get full text
Journal Article -
10
Optimization of pyrazolo[1,5-a]pyrimidine based compounds with pyridine scaffold: Synthesis, biological evaluation and molecular modeling study
Published in Arabian journal of chemistry (01-08-2022)“…Pyrazolopyrimidine heterocycle and its isosteres represent the main scaffold for many pharmacologically active drugs including anti-inflammatory agents. The…”
Get full text
Journal Article -
11
Synthesis, physicochemical properties, biological, molecular docking and DFT investigation of Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) complexes of the 4-[(5-oxo-4,5-dihydro-1,3-thiazol-2-yl)hydrazono]methyl}phenyl 4-methylbenzenesulfonate Schiff-base ligand
Published in Polyhedron (15-01-2023)“…[Display omitted] A new Schiff-base ligand, 4-[(4-oxo-4,5-dihydro-1,3-thiazol-2-yl)hydrazono]methylphenyl 4-methylbenzenesulfonate (L), and its Fe(III),…”
Get full text
Journal Article -
12
Design, Characterization, and DFT exploration of new mononuclear Fe(III) and Co(II) complexes based on Isatin-hydrazone derivative: Anti-inflammatory profiling and molecular docking insights
Published in Journal of molecular structure (05-01-2025)“…•Novel compounds involving Fe(III) (C1) and Co(II) (C2) ions were synthesized.•Structural elucidation employed a comprehensive array of spectroscopic…”
Get full text
Journal Article -
13
THREE CoMETHYLENE] AMINO}BENZOIC ACID: SYNTHESIS, STRUCTURAL, DFT, BIOLOGICAL AND MOLECULAR DOCKING INVESTIGATION
Published in Bulletin of the Chemical Society of Ethiopia (01-05-2024)“…New 2-[(4-[(4-methylphenyl)sulfonothioyl)methylene]aminobenzoic acid ligand-Co(II), Ni(II), and Cu(II) complexes are synthesized and characterized in this…”
Get full text
Journal Article -
14
New mononuclear Fe(III), Co(II), Ni(II), Cu(II), and Zn(II) complexes incorporating 4‐{[(2 hydroxyphenyl)imino]methyl}phenyl‐4‐methylbenzenesulfonate (HL): Synthesis, characterization, theoretical, anti‐inflammatory, and molecular docking investigation
Published in Applied organometallic chemistry (01-05-2022)“…Herein, new Fe(III), Co(II), Ni(II), Cu(II), and Zn(II) complexes incorporating 4‐{[(2‐hydroxyphenyl)imino]methyl}phenyl 4‐methylbenzenesulfonate Schiff‐base…”
Get full text
Journal Article -
15
A novel colorimetric chemosensor based on 2-[(carbamothioylhydrazono) methyl]phenyl 4-methylbenzenesulfonate (CHMPMBS) for the detection of Cu(II) in aqueous medium
Published in Research on chemical intermediates (01-05-2023)“…In this study, 2-[(carbamothioylhydrazono)methyl-phenyl-4-methylbenzenesulfonate (CHMPMBS) , which exhibits selective colorimetric chemosensor properties for…”
Get full text
Journal Article -
16
Preparation of some novel thiazolidinones, imidazolinones, and azetidinone bearing pyridine and pyrimidine moieties with antimicrobial activity
Published in Journal of heterocyclic chemistry (01-07-2020)“…By aiming to design new antimicrobial agents, we prepared new series of thiazolidin‐4‐ones(12a–d), imidazolin‐4‐ones(13a–d), and azetidin‐2‐ones (14a–d),…”
Get full text
Journal Article -
17
Design, fabrication and optical characterizations of pyrimidine fused quinolone carboxylate moiety for photodiode applications
Published in Optik (Stuttgart) (01-08-2020)“…•New heterocyclic of pyrimidine containing quinolone carboxylate moiety was obtained.•Remarkable optical behavior with the unique optical response…”
Get full text
Journal Article -
18
A selective colorimetric chemosensor for detecting Ni(II) in aqueous solutions based on 4-[{[4-(3-chlorophenyl)-1,3-thiazol-2-yl]hydrazono}methyl]phenyl 4-methyl benzene sulfonate (CTHMBS)
Published in Analytical sciences (01-04-2024)“…Among the toxic heavy metals, Ni(II) can cause a variety of side effects on human health, such as allergy, cardiovascular and kidney diseases, lung fibrosis,…”
Get full text
Journal Article -
19
Facile One-Pot Multicomponent Synthesis of Pyrazolo-Thiazole Substituted Pyridines with Potential Anti-Proliferative Activity: Synthesis, In Vitro and In Silico Studies
Published in Molecules (Basel, Switzerland) (22-05-2021)“…Pyrazolothiazole-substituted pyridine conjugates are an important class of heterocyclic compounds with an extensive variety of potential applications in the…”
Get full text
Journal Article -
20
New 1,2,3-Triazole-Containing Hybrids as Antitumor Candidates: Design, Click Reaction Synthesis, DFT Calculations, and Molecular Docking Study
Published in Molecules (Basel, Switzerland) (29-01-2021)“…In an effort to improve and achieve biologically active anticancer agents, a novel series of 1,2,3-triazole-containing hybrids were designed and efficiently…”
Get full text
Journal Article