Search Results - "A. Zen, Amer"
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In Vitro Evaluation and Bioinformatics Analysis of Schiff Bases Bearing Pyrazole Scaffold as Bioactive Agents: Antioxidant, Anti-Diabetic, Anti-Alzheimer, and Anti-Arthritic
Published in Molecules (Basel, Switzerland) (01-10-2023)“…In continuation of our research programs for the discovery, production, and development of the pharmacological activities of molecules for various disease…”
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Target-based anticancer glycyrrhetinic derivatives: Design, synthesis, biological assessment and molecular docking studies
Published in Bulletin of the Chemical Society of Ethiopia (01-07-2024)“…18-Glycyrrhetinic acid (GA) is regarded as the principal active component isolated from the Chinese medicinal plant of licorice root, and it has considerable…”
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Synthesis of new peptide-based macrocycles: Evaluation of their in vitro anti-proliferative activity and molecular dynamic simulation studies
Published in Bulletin of the Chemical Society of Ethiopia (01-01-2024)“…A simplified synthetic protocol was adopted for the preparation of the six novel cyclo-pentapeptide candidates of the structure cyclo-(m-phthaloyl)-bis-[L-Phe…”
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TCS/ZnCl2 as a controlled reagent for the Michael addition and heterocyclic cyclization based on the phenyl pyrazolone scaffold with docking validation as a Covid-19 protease inhibitor
Published in Bulletin of the Chemical Society of Ethiopia (01-01-2024)“…TCS/ZnCl2 is presented as a new catalyst for achieving the Michael addition adduct 5a-g by the reaction of phenyl pyrazolone 4 as the Michael donor and…”
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Novel Cobalt/vitamin B3 metal-organic framework as nano-catalyst in synthesis of some new bis-indole derivatives with staking validation towards Salmonella DNA
Published in Journal of organometallic chemistry (15-03-2024)“…•Cobalt/vitamin B3 metal-organic framework presented as nano-catalyst.•An efficient catalytic synthesis of some new bis-indole derivatives.•Stacking evaluation…”
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TCS/[ZnCl.sub.2] AS A CONTROLLED REAGENT FOR THE MICHAEL ADDITION AND HETEROCYCLIC CYCLIZATION BASED ON THE PHENYL PYRAZOLONE SCAFFOLD WITH DOCKING VALIDATION AS A COVID-19 PROTEASE INHIBITOR
Published in Bulletin of the Chemical Society of Ethiopia (01-04-2024)“…TCS/[ZnCl.sub.2] is presented as a new catalyst for achieving the Michael addition adduct 5a-g by the reaction of phenyl pyrazolone 4 as the Michael donor and…”
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SYNTHESIS OF NEW PEPTIDE-BASED MACROCYCLES: EVALUATION OF THEIR IN VITRO ANTIPROLIFERATIVE ACTIVITY AND MOLECULAR DYNAMIC SIMULATION STUDIES
Published in Bulletin of the Chemical Society of Ethiopia (01-04-2024)“…A simplified synthetic protocol was adopted for the preparation of the six novel cyclo-pentapeptide candidates of the structure cyclo-(m-phthaloyl)-bis-[L-Phe…”
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