CONFOCAL MICROSCOPY STUDY OF BIOLOGICAL PECULIARITIES OF SCAFFOLD MADE FROM RECOMBINANT SPIDER SILK

We studied the viability and dynamic of cell distribution during long-term cultivation of broblasts 3T3 in spider silk spidroin 1-based scaffold. Laser scanning confocal microscopy is shown to have advantages for visualization of cells situated on the external and internal surfaces of scaffold. Fibr...

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Bibliographic Details
Published in:	Vestnik transplantologii i iskusstvennykh organov Vol. 11; no. 2; pp. 54 - 59
Main Authors:	O. L. Pustovalova, I. I. Agapov, M. M. Moisenovich, P. S. Eremin, A. A. Kazulina, A. Y. Arhipova, A. A. Ramonova, V. G. Bogush, V. I. Sevastianov, M. P. Kirpichnikov
Format:	Journal Article
Language:	Russian
Published:	Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 01-05-2009
Subjects:	recombinant spider silk tissue engineering
Online Access:	Get full text
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Summary:	We studied the viability and dynamic of cell distribution during long-term cultivation of broblasts 3T3 in spider silk spidroin 1-based scaffold. Laser scanning confocal microscopy is shown to have advantages for visualization of cells situated on the external and internal surfaces of scaffold. Fibroblasts maintain high proliferative ability and viability during long term cultivation. Spidroin 1-based scaffold are the perspective materials for bioengineering.
ISSN:	1995-1191
DOI:	10.15825/1995-1191-2009-2-54-59