Search Results - "A. S. Silchenko"
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Brown Alga Metabolites – Inhibitors of Marine Organism Fucoidan Hydrolases
Published in Chemistry of natural compounds (01-03-2017)“…Fucoidan hydrolase inhibitors were discovered for the first time. Metabolites in the aqueous EtOH extract of Fucus evanescens inhibited specifically the…”
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Discovery of a fucoidan endo-4O-sulfatase: Regioselective 4O-desulfation of fucoidans and its effect on anticancer activity in vitro
Published in Carbohydrate polymers (01-11-2021)“…Fucoidans are a class of sulfated fucose-containing bioactive polysaccharides produced by brown algae. The biological effects exhibited by fucoidans are…”
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Radiosensitizing effect of the fucoidan from brown alga Fucus evanescens and its derivative in human cancer cells
Published in Carbohydrate polymers (01-02-2019)“…•The fucoidan FeF and its derivative FeHMP had comparable radiosensitizing effect in vitro.•FeF and FeHMP significantly increased X-rays effect on growth and…”
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In vitro and in vivo Immunoadjuvant Effects of the Enzymatically Modified Fucoidan
Published in Antibiotiki i himioterapiâ (18-07-2023)“…Objectives. No sulfated polysaccharides (fucoidans) has been declared as the pharmaceutical substances, adjuvants, etc., which is associated with the problems…”
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Immunomodulatory properties of Cumaside
Published in International immunopharmacology (01-07-2006)“…The medical lead, so-called Cumaside, was created on the basis of triterpene oligoglycosides from the Far-Eastern edible sea cucumber (holothurian) Cucumaria…”
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Effect of Sulfated Polysaccharides from Marine Hydrobionts on Humoral Immune Response to Ovalbumin in Mice
Published in Bulletin of experimental biology and medicine (01-06-2020)“…Adjuvant activity of fucoidans in experimental vaccine compositions with ovalbumin was studied on a mouse model. Compositions with sulfated polysaccharides…”
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Alginate Lyases: Substrates, Structure, Properties, and Prospects of Application
Published in Russian journal of bioorganic chemistry (01-07-2018)“…Alginate lyases catalyze degradation of alginic acids and their salts, alginates, which are one of the main components of brown algae cell walls and comprise…”
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Taxonomic significance and ecological role of triterpene glycosides from holothurians
Published in Biology bulletin of the Russian Academy of Sciences (01-11-2016)“…The results of chemotaxonomic research on triterpene glycosides of holothurians (Holothurioidea, Echinodermata) and studies on the ecological role of these…”
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Determination of cucumarioside A2-2 in mouse spleen by radiospectroscopy, MALDI-MS and MALDI-IMS
Published in European journal of pharmaceutical sciences (16-07-2013)“…[Display omitted] The distribution of triterpene glycoside cucumarioside A2-2, the main compound of medical lead Cumaside in immunodeficiency diseases, in…”
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Antitumor activity of cucumarioside A2-2
Published in Chemotherapy (Basel) (01-01-2014)“…The cytotoxic activity of sea cucumber glycosides against different types of cells and cell lines, including human tumor cell lines, has been studied for many…”
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Immunomodulatory properties of frondoside A, a major triterpene glycoside from the North Atlantic commercially harvested sea cucumber Cucumaria frondosa
Published in Journal of medicinal food (01-09-2008)“…Frondoside A, a major triterpene glycoside from North Atlantic commercially harvested sea cucumber Cucumaria frondosa, possesses strong immunomodulatory…”
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Effect of Sulfated Polysaccharides from Brown Alga Fucus evanescens and Their Enzymatic Transformation Product on Functional Activity of Innate Immunity Cells.
Published in Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] (2016)“…The effect of sulfated polysaccharides (PS) from brown alga Fucus evanescens and their enzymatic transformation and low molecular weight product on the…”
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Catalytic properties and amino acid sequence of endo-1→3-β-D-glucanase from the marine mollusk Tapes literata
Published in Biochemistry (Moscow) (01-08-2012)“…A specific 1→3-β-D-glucanase with molecular mass 37 kDa was isolated in homogeneous state from crystalline style of the commercial marine mollusk Tapes…”
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Estrogenic activity of triterpene glycosides in yeast two-hybrid assay
Published in The Journal of steroid biochemistry and molecular biology (01-11-2006)“…Estrogenic potency of six triterpene glycosides, Holothurin A, Holotoxin A 1, Frondoside A, Cucumarioside A 2-2 and Cauloside C, that are natural products and…”
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Monosulfated triterpene glycosides from Cucumaria okhotensis Levin et Stepanov, a new species of sea cucumbers from sea of Okhotsk
Published in Russian journal of bioorganic chemistry (01-02-2007)“…Three compounds were isolated from the fraction of monosulfated triterpene glycosides from Cucumaria okhotensis, a new sea cucumber species, and their…”
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Structure of the major triterpene glycoside from the sea cucumber Stichopus mollis and evidence to reclassify this species into the new genus Australostichopus
Published in Biochemical systematics and ecology (01-07-2004)“…The major glycoside component from the New Zealand sea cucumber Stichopus mollis (Stichopodidae, Aspidochirotida), was identified as neothyonidioside (1), a…”
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Triterpene Glycosides from the Deep-Water North-Pacific Sea Cucumber Synallactes nozawai Mitsukuri
Published in Journal of natural products (Washington, D.C.) (01-12-2002)“…Five non-sulfated triterpene glycosides, synallactosides A(1) (1), A(2) (2), B(1) (3), B(2) (4), and C (5), have been isolated from the sea cucumber…”
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Expression and biochemical characterization of two recombinant fucoidanases from the marine bacterium Wenyingzhuangia fucanilytica CZ1127T
Published in International journal of biological macromolecules (01-12-2020)“…Genomic analysis of the marine bacterium Wenyingzhuangia fucanilytica CZ1127T revealed the presence of four fucoidanase genes fwf1, fwf2, fwf3, fwf4 that…”
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Effect of Sulfated Polysaccharides from Brown Alga Fucus evanescens and Their Enzymatic Transformation Product on Functional Activity of Innate Immunity Cells
Published in Антибиотики и Химиотерапия (01-05-2020)“…The effect of sulfated polysaccharides (PS) from brown alga Fucus evanescens and their enzymatic transformation and low molecular weight product on the…”
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Phenotypic Changes in Subpopulations of Human NK and NKT Cells Induced
Published in Антибиотики и Химиотерапия (01-05-2020)“…The article studies the effect of sulfated polysaccharide extracted from brown algae Fucus evanescens(fucoidan) and the product of its enzymatic transformation…”
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