Search Results - "A. Panoskaltsis-Mortari"

L‐Selectin Is Dispensable for T Regulatory Cell Function Postallogeneic Bone Marrow Transplantation by Carlson, M. J., Fulton, L. M., Coghill, J. M., West, M. L., Burgents, J. E., Wan, Y., Panoskaltsis‐Mortari, A., Tedder, T. F., Blazar, B. R., Serody, J. S.

“…In murine models, the adoptive transfer of CD4+/CD25+ regulatory T cells (Tregs) inhibited graft‐versus‐host disease (GvHD). Previous work has indicated a…”
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Urinary-derived human chorionic gonadotropin to induce tolerance and promote healing in steroid-refractory GvHD by Holtan, S G, Panoskaltsis-Mortari, A

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In Vitro Analysis of RBC-Mediated Lung Injury in Prolonged Ex Vivo Lung Perfusion by Spratt, J.R, Loor, G, Mattison, L.M, Meyer, C, Ehrhardt, M, Helms, H, Panoskaltsis-Mortari, A

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Lung Transplantation from DCD Donors After Prolonged Normothermic Portable EVLP by Spratt, J.R, Mattison, L.M, Iaizzo, P.A, Meyer, C, Iles, T.L, Panoskaltsis-Mortari, A, Loor, G

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Donor and recipient plasma follistatin levels are associated with acute GvHD in Blood and Marrow Transplant Clinical Trials Network 0402 by Turcotte, L M, DeFor, T E, Newell, L F, Cutler, C S, Verneris, M R, Wu, J, Howard, A, MacMillan, M L, Antin, J H, Vercellotti, G M, Slungaard, Ane, Blazar, B R, Weisdorf, D J, Panoskaltsis-Mortari, A, Holtan, S G

“…Follistatin is an angiogenic factor elevated in the circulation after allogeneic hematopoietic cell transplantation (HCT). Elevations in follistatin plasma…”
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Low EGF in myeloablative allotransplantation: association with severe acute GvHD in BMT CTN 0402 by Holtan, S G, Newell, L F, Cutler, C, Verneris, M R, DeFor, T E, Wu, J, Howard, A, MacMillan, M L, Antin, J H, Blazar, B R, Weisdorf, D J, Panoskaltsis-Mortari, A

“…Epidermal growth factor (EGF) is a recently described biomarker of acute GvHD (aGvHD). Whether low plasma EGF prior to hematopoietic cell transplantation (HCT)…”
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Low day +100 serum epidermal growth factor levels are associated with acute GvHD after allogeneic hematopoietic cell transplantation by He, F, Verneris, M R, Cooley, S, Blazar, B R, MacMillan, M L, Newell, L F, Panoskaltsis-Mortari, A, DeFor, T, Weisdorf, D J, Holtan, S G

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LOW LEVELS OF IMMUNO‐SUPPRESSOR CELLS PROMOTE RESPONSES TO A HAPLOIDENTICAL NATURAL KILLER CELL THERAPY AND INDUCE REMISSIONS IN NON‐HODGKIN LYMPHOMA by Bachanova, V., Sarhan, D., Defor, T., Cooley, S., Panoskaltsis‐Mortari, A.

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Prolonged Lung Preservation at 24 Hours Using Donor Whole Blood Perfusion in the Organ Care System (OCS) by Loor, G, Howard, B, Iles, T, Mattison, L, Meyer, P, Day, T, Panoskaltsis-Mortari, A, Kelly, R, Iaizzo, P

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IL-2-based immunotherapy after autologous transplantation for lymphoma and breast cancer induces immune activation and cytokine release: a phase I II trial by BURNS, L. J, WEISDORF, D. J, MILLER, J. S, DEFOR, T. E, VESOLE, D. H, REPKA, T. L, BLAZAR, B. R, BURGER, S. R, PANOSKALTSIS-MORTARI, A, KEEVER-TAYLOR, C. A, ZHANG, M-J

“…We determined the safety, immune activating effects, and potential efficacy of i.v. infusion of ex vivo interleukin-2 (IL-2) activated natural killer (NK)…”
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CD47 (integrin-associated protein) engagement of dendritic cell and macrophage counterreceptors is required to prevent the clearance of donor lymphohematopoietic cells by Blazar, B R, Lindberg, F P, Ingulli, E, Panoskaltsis-Mortari, A, Oldenborg, P A, Iizuka, K, Yokoyama, W M, Taylor, P A

“…Integrin-associated protein (CD47) is a broadly expressed protein that costimulates T cells, facilitates leukocyte migration, and inhibits macrophage scavenger…”
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Ligation of 4-1BB (CDw137) Regulates Graft-Versus-Host Disease, Graft-Versus-Leukemia, and Graft Rejection in Allogeneic Bone Marrow Transplant Recipients by Blazar, Bruce R, Kwon, Byoung S, Panoskaltsis-Mortari, Angela, Kwak, Kyu B, Peschon, Jacques J, Taylor, Patricia A

“…4-1BB is expressed on activated CD4(+) and CD8(+) T cells; its ligand, 4-1BB ligand is expressed on APCs. Despite expression on both T cell subpopulations,…”
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Fully MHC-matched allogeneic hematopoietic stem cell transplantation in SIV-infected, cART-suppressed Mauritian cynomolgus macaques indicates GVHD as a reservoir clearance mechanism by H.L. Wu, B.J. Burwitz, S.A. Abdulhaqq, C. Shriver-Munsch, T. Swanson, A.W. Legasse, K.B. Hammond, J.S. Reed, M. Northrup, S.L. Junell, J.M. Greene, G.M. Webb, B.N. Bimber, W. Laub, P. Kievit, R. MacAllister, M.K. Axthelm, R. Ducore, A. Lewis, L. Colgin, T.R. Hobbs, L.D. Martin, C.R. Thomas, A. Panoskaltsis-Mortari, G. Meyers, J.J. Stanton, R.T. Maziarz, J.B. Sacha

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46LB A nonhuman primate model of fully MHC-matched allogeneic stem cell transplantation to study HIV reservoir clearance by B. Burwitz, J. Stanton, C. Shriver-Munsch, T. Swanson, A. Legasse, K. Hammond, S. Abdulhaqq, H. Wu, R. Macallister, M. Axthelm, T. Hobbs, L. Martin, R. Ducore, A. Lewis, L. Colgin, A. Panoskaltsis-Mortari, G. Meyers, R. Maziarz, J. Sacha

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Sex-Based Differences in Vascular Repair With Bone Marrow Cell Therapy: Relevance of Regulatory and Th2-type Cytokines by Zenovich, A.G, Panoskaltsis-Mortari, A, Caron, G.J, Kolb, A.G, Fremming, R, Nelson, W.D, Taylor, D.A

“…Abstract Objectives There are differences in symptoms, risk stratification, and efficacy of pharmacological treatments between men and women with coronary…”
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In situ hybridization with digoxigenin-labeled RNA probes: facts and artifacts by Panoskaltsis-Mortari, A, Bucy, R P

“…We have developed an easy, stream-lined yet sensitive protocol for in situ hybridization to mRNA in frozen tissue sections or cytospins using…”
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Induction of monocyte– and T-cell–attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation by Panoskaltsis-Mortari, Angela, Strieter, Robert M., Hermanson, John R., Fegeding, Konstantin V., Murphy, William J., Farrell, Catherine L., Lacey, David L., Blazar, Bruce R.

“…Idiopathic pneumonia syndrome (IPS) is a significant complication following bone marrow transplantation (BMT). We have developed a murine model in which severe…”
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3D Bioprinted In Vitro Metastatic Models via Reconstruction of Tumor Microenvironments by Meng, Fanben, Meyer, Carolyn M., Joung, Daeha, Vallera, Daniel A., McAlpine, Michael C., Panoskaltsis‐Mortari, Angela

“…The development of 3D in vitro models capable of recapitulating native tumor microenvironments could improve the translatability of potential anticancer drugs…”
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Coblockade of the LFA1:ICAM and CD28/CTLA4:B7 pathways is a highly effective means of preventing acute lethal graft-versus-host disease induced by fully major histocompatibility complex-disparate donor grafts by BLAZAR, B. R, TAYLOR, P. A, PANOSKATSIS-MORTARI, A, GRAY, G. S, VALLERA, D. A

“…We have developed an in vitro system in which C57BL/6 donor splenocytes are exposed to B10.BR host alloantigens in the context of deficient CD28:B7 signaling…”
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CD28/B7 interactions are required for sustaining the graft-versus- leukemia effect of delayed post-bone marrow transplantation splenocyte infusion in murine recipients of myeloid or lymphoid leukemia cells by Blazar, BR, Taylor, PA, Boyer, MW, Panoskaltsis-Mortari, A, Allison, JP, Vallera, DA

“…Graft-vs-leukemia (GVL) can reduce relapse rates after bone marrow transplantation (BMT). Delayed lymphocyte infusion (DLI) post-BMT can mediate a potent GVL…”
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