Search Results - "A. Mesri"
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Human Viral Oncogenesis: A Cancer Hallmarks Analysis
Published in Cell host & microbe (12-03-2014)“…Approximately 12% of all human cancers are caused by oncoviruses. Human viral oncogenesis is complex, and only a small percentage of the infected individuals…”
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Glycosylation-Dependent Lectin-Receptor Interactions Preserve Angiogenesis in Anti-VEGF Refractory Tumors
Published in Cell (13-02-2014)“…The clinical benefit conferred by vascular endothelial growth factors (VEGF)-targeted therapies is variable, and tumors from treated patients eventually…”
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Molecular and cellular mechanisms of KSHV oncogenesis of Kaposi's sarcoma associated with HIV/AIDS
Published in PLoS pathogens (01-07-2014)“… Evidence pointing to the existence of a circulating KS progenitor, which is increased in AIDS-KS [11], includes: (a) KS spindle cells in renal-transplant…”
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High-throughput sequencing analysis of a “hit and run” cell and animal model of KSHV tumorigenesis
Published in PLoS pathogens (01-06-2020)“…Kaposi's sarcoma (KS), is an AIDS-associated neoplasm caused by the KS herpesvirus (KSHV/ HHV-8). KSHV-induced sarcomagenesis is the consequence of oncogenic…”
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KSHV-induced ligand mediated activation of PDGF receptor-alpha drives Kaposi's sarcomagenesis
Published in PLoS pathogens (01-07-2018)“…Kaposi's sarcoma (KS) herpesvirus (KSHV) causes KS, an angiogenic AIDS-associated spindle-cell neoplasm, by activating host oncogenic signaling cascades…”
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A role of hypoxia-inducible factor 1 alpha in Murine Gammaherpesvirus 68 (MHV68) lytic replication and reactivation from latency
Published in PLoS pathogens (06-12-2019)“…The hypoxia-inducible factor 1 alpha (HIF1α) protein and the hypoxic microenvironment are critical for infection and pathogenesis by the oncogenic…”
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PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment
Published in PLoS pathogens (01-12-2019)“…Kaposi's sarcoma (KS) is an AIDS-defining cancer caused by the KS-associated herpesvirus (KSHV). Unanswered questions regarding KS are its cellular ontology…”
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KSHV G-protein coupled receptor vGPCR oncogenic signaling upregulation of Cyclooxygenase-2 expression mediates angiogenesis and tumorigenesis in Kaposi's sarcoma
Published in PLoS pathogens (15-10-2020)“…Kaposi's sarcoma-associated herpesvirus (KSHV) vGPCR is a constitutively active G protein-coupled receptor that subverts proliferative and inflammatory…”
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A major role for Nrf2 transcription factors in cell transformation by KSHV encoded oncogenes
Published in Frontiers in oncology (21-09-2022)“…Kaposi’s sarcoma (KS) is the most common tumor in AIDS patients. The highly vascularized patient’s skin lesions are composed of cells derived from the…”
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10
Monitoring Rice Land Changes Using GIS and RS
Published in Māshīnʹhā-yi kishāvarzī (01-12-2022)“…IntroductionRice is the fourth most consumed grain worldwide. In recent years, monitoring the area under rice cultivation; as a strategic crop in Gilan…”
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Efficacious proteasome/HDAC inhibitor combination therapy for primary effusion lymphoma
Published in The Journal of clinical investigation (01-06-2013)“…Primary effusion lymphoma (PEL) is a rare form of aggressive B cell lymphoma caused by Kaposi's sarcoma-associated herpesvirus (KSHV). Current chemotherapy…”
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12
Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway
Published in Oncogene (01-07-2015)“…Kaposi sarcoma-associated herpesvirus (KSHV) is an oncogenic virus and the culprit behind the human disease Kaposi sarcoma (KS), an AIDS-defining malignancy…”
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Performance of physical treatment method and different commercial antiscalants to control scaling deposition in desalination plant
Published in Desalination (03-08-2015)“…A literature survey was conducted at Kuwait Institute for Scientific Research (KISR), to investigate the effect of magnetic treatment method (MTM) on the water…”
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Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral IL-6 (vIL-6) Enhances Immunoglobulin Class-Switch Recombination
Published in Frontiers in microbiology (18-12-2018)“…Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic gamma-herpesvirus that causes AIDS-associated Kaposi sarcoma (KS) and several…”
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A Non-Coding RNA Network Involved in KSHV Tumorigenesis
Published in Frontiers in oncology (16-06-2021)“…Regulatory pathways involving non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNA), have gained great relevance due to their…”
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Activation of the Unfolded Protein Response by 2-Deoxy-d-Glucose Inhibits Kaposi's Sarcoma-Associated Herpesvirus Replication and Gene Expression
Published in Antimicrobial Agents and Chemotherapy (01-11-2012)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma
Published in Proceedings of the National Academy of Sciences - PNAS (26-05-2009)“…Kaposi's sarcoma (KS) is the major AIDS-associated malignancy. It is characterized by the proliferation of spindle cells, inflammatory infiltrate, and aberrant…”
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In Vivo-Restricted and Reversible Malignancy Induced by Human Herpesvirus-8 KSHV: A Cell and Animal Model of Virally Induced Kaposi's Sarcoma
Published in Cancer cell (01-03-2007)“…Transfection of a Kaposi's sarcoma (KS) herpesvirus (KSHV) Bacterial Artificial Chromosome (KSHVBac36) into mouse bone marrow endothelial-lineage cells…”
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G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator
Published in Nature (London) (01-01-1998)“…The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8) is a γ-2 herpesvirus that is implicated in the pathogenesis of Kaposi's sarcoma, and of primary…”
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Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma
Published in Proceedings of the National Academy of Sciences - PNAS (20-07-2010)“…Primary effusion lymphoma (PEL) is an aggressive B-cell lymphoma most commonly diagnosed in HIV-positive patients and universally associated with Kaposi's…”
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