Search Results - "A. Gurgel Rocha, Clarissa"

Hedgehog components are overexpressed in a series of liver cancer cases by Sales, Caroline Brandi Schlaepfer, Dias, Rosane Borges, de Faro Valverde, Ludmila, Bomfim, Larissa M., Silva, Lais Almeida, de Carvalho, Nanashara C., Bastos, Jorge Luiz Andrade, Tilli, Tatiana Martins, Rocha, Gisele Vieira, Soares, Milena Botelho Pereira, de Freitas, Luiz Antonio Rodrigues, Gurgel Rocha, Clarissa A., Bezerra, Daniel P.

“…Liver cancers, including hepatocellular carcinoma (HCC), are the sixth most common cancer and the third leading cause of cancer-related death worldwide,…”
Get full text

Ru(II)-thymine complex causes DNA damage and apoptotic cell death in human colon carcinoma HCT116 cells mediated by JNK/p38/ERK1/2 via a p53-independent signaling by Silva, Suellen L. R., Baliza, Ingrid R. S., Dias, Rosane B., Sales, Caroline B. S., Rocha, Clarissa A. Gurgel, Soares, Milena B. P., Correa, Rodrigo S., Batista, Alzir A., Bezerra, Daniel P.

“…Ru(II)-thymine complex [Ru(PPh 3 ) 2 (Thy)(bipy)]PF 6 (where PPh 3  = triphenylphosphine, Thy = thyminate and bipy = 2,2′-bipyridine) is a potent cytotoxic…”
Get full text

Ruthenium complex containing 1,3-thiazolidine-2-thione inhibits hepatic cancer stem cells by suppressing Akt/mTOR signalling and leading to apoptotic and autophagic cell death by Neves, Sara P., Bomfim, Larissa M., Kataura, Tetsushi, Carvalho, Sabrine G., Nogueira, Mateus L., Dias, Rosane B., Valverde, Ludmila de F., Gurgel Rocha, Clarissa A., Soares, Milena B.P., Silva, Monize M. da, Batista, Alzir A., Korolchuk, Viktor I., Bezerra, Daniel P.

“…Hepatic cancer is one of the main causes of cancer-related death worldwide. Cancer stem cells (CSCs) are a unique subset of cancer cells that promote tumour…”
Get full text

Duguetia pycnastera Sandwith (Annonaceae) Leaf Essential Oil Inhibits HepG2 Cell Growth In Vitro and In Vivo by Costa, Emmanoel V, de Souza, César A S, Galvão, Alexandre F C, Silva, Valdenizia R, Santos, Luciano de S, Dias, Rosane B, Rocha, Clarissa A Gurgel, Soares, Milena B P, da Silva, Felipe M A, Koolen, Hector H F, Bezerra, Daniel P

“…Duguetia pycnastera Sandwith (Annonaceae) is a tropical tree that can be found in the Guyanas, Bolivia, Venezuela, and Brazil. In Brazil, it is popularly known…”
Get full text

Antitumor Effect of Guatteria olivacea R. E. Fr. (Annonaceae) Leaf Essential Oil in Liver Cancer by Galvão, Alexandre F. C., Araújo, Morgana de S., Silva, Valdenizia R., Santos, Luciano de S., Dias, Rosane B., Rocha, Clarissa A. Gurgel, Soares, Milena B. P., Silva, Felipe M. A. da, Koolen, Hector H. F., Zengin, Gokhan, Costa, Emmanoel V., Bezerra, Daniel P.

“…Guatteria olivacea R. E. Fries (synonym Guatteria punctata (Aubl.) R.A. Howard) is a tree of 10–27 m tall popularly known as “envira-bobó”, “envira-fofa”,…”
Get full text

Exploring beyond Common Cell Death Pathways in Oral Cancer: A Systematic Review by Siquara da Rocha, Leonardo de Oliveira, de Morais, Everton Freitas, de Oliveira, Lilianny Querino Rocha, Barbosa, Andressa Vollono, Lambert, Daniel W, Gurgel Rocha, Clarissa A, Coletta, Ricardo D

“…Oral squamous cell carcinoma (OSCC) is the most common and lethal type of head and neck cancer in the world. Variable response and acquisition of resistance to…”
Get full text

Mapping Cell-in-Cell Structures in Oral Squamous Cell Carcinoma by Siquara da Rocha, Leonardo de Oliveira, Souza, Bruno Solano de Freitas, Coletta, Ricardo Della, Lambert, Daniel W., Gurgel Rocha, Clarissa A.

“…Cell-in-cell (CIC) structures contribute to tumor aggressiveness and poor prognosis in oral squamous cell carcinoma (OSCC). In vitro 3D models may contribute…”
Get full text

Tingenone and 22-hydroxytingenone target oxidative stress through downregulation of thioredoxin, leading to DNA double-strand break and JNK/p38-mediated apoptosis in acute myeloid leukemia HL-60 cells by Rodrigues, Ana Carolina B. da C., Bomfim, Larissa M., Neves, Sara P., Soares, Milena B.P., Dias, Rosane B., Valverde, Ludmila F., Rocha, Clarissa A. Gurgel, Costa, Emmanoel V., da Silva, Felipe M.A., Rocha, Waldireny C., Koolen, Hector H.F., Bezerra, Daniel P.

“…Acute myeloid leukemia (AML) is the most lethal form of leukemia. Standard anti-AML treatment remains almost unchanged for decades. Tingenone (TG) and…”
Get full text

Cyperus articulatus L. (Cyperaceae) Rhizome Essential Oil Causes Cell Cycle Arrest in the G2/M Phase and Cell Death in HepG2 Cells and Inhibits the Development of Tumors in a Xenograft Model by Nogueira, Mateus L., Lima, Emilly J. S. P. de, Adrião, Asenate A. X., Fontes, Sheila S., Silva, Valdenizia R., Santos, Luciano de S., Soares, Milena B. P., Dias, Rosane B., Rocha, Clarissa A. Gurgel, Costa, Emmanoel V., Silva, Felipe M. A. da, Vannier-Santos, Marcos A., Cardozo, Nállarett M. D., Koolen, Hector H. F., Bezerra, Daniel P.

“…Cyperus articulatus L. (Cyperaceae), popularly known in Brazil as “priprioca” or “piriprioca”, is a tropical and subtropical plant used in popular medical…”
Get full text

Combination Therapy of Curcumin and Disulfiram Synergistically Inhibits the Growth of B16-F10 Melanoma Cells by Inducing Oxidative Stress by Fontes, Sheila S, Nogueira, Mateus L, Dias, Rosane B, Rocha, Clarissa A. Gurgel, Soares, Milena B. P, Vannier-Santos, Marcos A, Bezerra, Daniel P

“…Oxidative stress plays a central role in the pathophysiology of melanoma. Curcumin (CUR) is a polyphenolic phytochemical that stimulates reactive oxygen…”
Get full text

Essential oil from leaves of Conobea scoparioides (Cham. & Schltdl.) Benth. (Plantaginaceae) causes cell death in HepG2 cells and inhibits tumor development in a xenograft model by Lima, Emilly J.S.P. de, Fontes, Sheila S., Nogueira, Mateus L., Silva, Valdenizia R., Santos, Luciano de S., D’Elia, Gigliola M.A., Dias, Rosane B., Sales, Caroline B.S., Rocha, Clarissa A. Gurgel, Vannier-Santos, Marcos A., Soares, Milena B.P., Costa, Emmanoel V., Silva, Felipe M.A. da, Koolen, Hector H.F., Bezerra, Daniel P.

“…Conobea scoparioides (Cham. & Schltdl.) Benth. (syn. Sphaerotheca scoparioides Cham. & Schldtl.) (Plantaginaceae), popularly known as "pataqueira",…”
Get full text

Ruthenium Complexes With Piplartine Cause Apoptosis Through MAPK Signaling by a p53-Dependent Pathway in Human Colon Carcinoma Cells and Inhibit Tumor Development in a Xenograft Model by Baliza, Ingrid R S, Silva, Suellen L R, Santos, Luciano de S, Neto, João H Araujo, Dias, Rosane B, Sales, Caroline B S, Rocha, Clarissa A Gurgel, Soares, Milena B P, Batista, Alzir A, Bezerra, Daniel P

“…Ruthenium complexes with piplartine, [Ru(piplartine)(dppf)(bipy)](PF ) ( ) and [Ru(piplartine)(dppb)(bipy)](PF ) ( ) (dppf = 1,1-bis(diphenylphosphino)…”
Get full text

Enhancing scaffold-free spheroid models: 3D cell bioprinting method for metastatic HSC3–Oral squamous carcinoma cell line by de Araújo, Taís Bacelar Sacramento, Nogueira, Raphael Luís Rocha, Siquara da Rocha, Leonardo de Oliveira, Bastos, Iasmin Nogueira, Dias, Rosane Borges, Souza, Bruno Solano De Freitas, Lambert, Daniel William, Coletta, Ricardo D., Silva, Viviane Aline Oliveira, Gurgel Rocha, Clarissa A.

“…3D in vitro systems offer advantages over the shortcomings of two-dimensional models by simulating the morphological and functional features of in vivo-like…”
Get full text

Bithionol eliminates acute myeloid leukaemia stem-like cells by suppressing NF-κB signalling and inducing oxidative stress, leading to apoptosis and ferroptosis by Dias, Ingrid R. S. B., Costa, Rafaela G. A., Rodrigues, Ana Carolina B. da C., Silva, Suellen L. R., Oliveira, Maiara de S., Soares, Milena B. P., Dias, Rosane B., Valverde, Ludmila F., Gurgel Rocha, Clarissa A., Cairns, Lauren V., Mills, Ken I., Bezerra, Daniel P.

“…Acute myeloid leukaemia (AML) is a lethal bone marrow neoplasm caused by genetic alterations in blood cell progenitors. Leukaemic stem cells (LSCs) are…”
Get full text

Arsenic Trioxide Triggers Apoptosis of Metastatic Oral Squamous Cells Carcinoma with Concomitant Downregulation of GLI1 in Hedgehog Signaling by Nogueira, Raphael Luís Rocha, de Araújo, Taís Bacelar Sacramento, Valverde, Ludmila Faro, Silva, Viviane Aline Oliveira, Cavalcante, Bruno Raphael Ribeiro, Rossi, Erik Aranha, Allahdadi, Kyan James, Dos Reis, Mitermayer Galvão, Pereira, Thiago Almeida, Coletta, Ricardo D, Bezerra, Daniel Pereira, de Freitas Souza, Bruno Solano, Dias, Rosane Borges, Rocha, Clarissa A Gurgel

“…Given the lack of advances in Oral Squamous Cell Carcinoma (OSCC) therapy in recent years, pharmacological strategies to block OSCC-related signaling pathways…”
Get full text

Ruthenium(II) complexes with 6-methyl-2-thiouracil selectively reduce cell proliferation, cause DNA double-strand break and trigger caspase-mediated apoptosis through JNK/p38 pathways in human acute promyelocytic leukemia cells by Bomfim, Larissa M., de Araujo, Fênix A., Dias, Rosane B., Sales, Caroline B. S., Rocha, Clarissa A. Gurgel, Correa, Rodrigo S., Soares, Milena B. P., Batista, Alzir A., Bezerra, Daniel P.

“…Ruthenium(II) complexes with 6-methyl-2-thiouracil cis -[Ru(6m2tu) 2 (PPh 3 ) 2 ] ( 1 ) and [Ru(6m2tu) 2 (dppb)] ( 2 ) (where PPh 3 =  triphenylphosphine; dppb…”
Get full text

In vitro and in vivo inhibition of HCT116 cells by essential oils from bark and leaves of Virola surinamensis (Rol. ex Rottb.) Warb. (Myristicaceae) by Anunciação, Talita A. da, Costa, Rafaela G.A., Lima, Emilly J.S.P. de, Silva, Valdenizia R., Santos, Luciano de S., Soares, Milena B.P., Dias, Rosane B., Rocha, Clarissa A. Gurgel, Costa, Emmanoel V., Silva, Felipe M.A. da, Koolen, Hector H.F., Bezerra, Daniel P.

“…Virola surinamensis (Rol. ex Rottb.) Warb. (Myristicaceae), popularly known in Brazil as “mucuíba”, “ucuúba”, “ucuúba-branca” or “ucuúba do igapó”, is a…”
Get full text

Antitumour Activity of the Microencapsulation of Annona vepretorum Essential Oil by Bomfim, Larissa M., Menezes, Leociley R. A., Rodrigues, Ana Carolina B. C., Dias, Rosane B., Gurgel Rocha, Clarissa A., Soares, Milena B. P., Neto, Albertino F. S., Nascimento, Magaly P., Campos, Adriana F., Silva, Lidércia C. R. C. e., Costa, Emmanoel V., Bezerra, Daniel P.

“…Annona vepretorum Mart. (Annonaceae), popularly known as ‘bruteira’, has nutritional and medicinal uses. This study investigated the chemical composition and…”
Get full text

MCM3: A Novel Proliferation Marker in Oral Squamous Cell Carcinoma by Valverde, Ludmila de F, de Freitas, Raíza D, Pereira, Thiago de A, de Resende, Marina F, Agra, Ivan M G, Dos Santos, Jean N, Dos Reis, Mitermayer G, Sales, Caroline B S, Gurgel Rocha, Clarissa A

“…The present study sought to evaluate and compare the immunoexpression of proteins minichromosome maintenance (MCM) 3 and Ki-67 in oral squamous cell carcinoma…”
Get full text

Antitumor Properties of the Essential Oil From the Leaves of Duguetia gardneriana by Rodrigues, Ana Carolina B C, Bomfim, Larissa M, Neves, Sara P, Menezes, Leociley R A, Dias, Rosane B, Soares, Milena B P, Prata, Ana Paula N, Rocha, Clarissa A Gurgel, Costa, Emmanoel V, Bezerra, Daniel P

“…Duguetia gardneriana, popularly known in the Brazilian northeast as "jaquinha", is a species belonging to the family Annonaceae. The aim of this work was to…”
Get more information