Search Results - "A. Gamal"
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1
Limb lengthening history, evolution, complications and current concepts
Published in Journal of orthopaedics and traumatology (05-03-2020)“…Limb lengthening continues to be a real challenge to both the patient and the orthopaedic surgeon. Although it is not a difficult operative problem, there is a…”
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2
Ciprofloxacin Controlled-Solid Lipid Nanoparticles: Characterization, In Vitro Release, and Antibacterial Activity Assessment
Published in BioMed research international (01-01-2017)“…The objective of this research was to formulate ciprofloxacin (CIP) in solid lipid nanoparticles (SLNs) in an attempt to develop a controlled drug delivery…”
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3
In silico drug discovery of SIRT2 inhibitors from natural source as anticancer agents
Published in Scientific reports (07-02-2023)“…Sirtuin 2 (SIRT2) is a member of the sirtuin protein family, which includes lysine deacylases that are NAD + -dependent and organize several biological…”
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4
Screening of different drug design tools to predict the mode of action of steroidal derivatives as anti-cancer agents
Published in Steroids (01-12-2019)“…[Display omitted] •Molecular docking methods can be used to explore how the steroid derivatives conformations can adopt within the macromolecules involved in…”
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5
Lipase‐Catalyzed Dynamic Kinetic Resolution of C1‐ and C2‐Symmetric Racemic Axially Chiral 2,2′‐Dihydroxy‐1,1′‐biaryls
Published in Angewandte Chemie International Edition (06-08-2018)“…We have discovered that the racemization of configurationally stable, axially chiral 2,2′‐dihydroxy‐1,1′‐biaryls proceeds with a catalytic amount of a…”
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6
Exploring Natural Product Activity and Species Source Candidates for Hunting ABCB1 Transporter Inhibitors: An In Silico Drug Discovery Study
Published in Molecules (Basel, Switzerland) (12-05-2022)“…The P-glycoprotein (P-gp/ABCB1) is responsible for a xenobiotic efflux pump that shackles intracellular drug accumulation. Additionally, it is included in the…”
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7
Lipase-Catalyzed Dynamic Kinetic Resolution of C 1 - and C 2 -Symmetric Racemic Axially Chiral 2,2'-Dihydroxy-1,1'-biaryls
Published in Angewandte Chemie International Edition (06-08-2018)“…We have discovered that the racemization of configurationally stable, axially chiral 2,2'-dihydroxy-1,1'-biaryls proceeds with a catalytic amount of a…”
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8
Evaluation of some anions in groundwater in Riyadh, Saudi Arabia, and human health risk assessment of nitrate and fluoride
Published in Scientific reports (21-10-2024)“…Groundwater is a vital source of water for human and agricultural use in many parts of the world. The purpose of this research was to establish the quality of…”
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9
Quantum Computational Investigation of (E)-1-(4-methoxyphenyl)-5-methyl-N′-(3-phenoxybenzylidene)-1H-1,2,3-triazole-4-carbohydrazide
Published in Molecules (Basel, Switzerland) (28-03-2022)“…The title compound was synthesized and structurally characterized. Theoretical IR, NMR (with the GIAO technique), UV, and nonlinear optical properties (NLO) in…”
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10
Development of an LC-MS/MS Method for Quantification of Sapitinib in Human Liver Microsomes: In Silico and In Vitro Metabolic Stability Evaluation
Published in Molecules (Basel, Switzerland) (01-03-2023)“…Sapitinib (AZD8931, SPT) is a tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR) family (pan-erbB). In multiple tumor cell lines, STP has…”
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11
Untapped Potential of Marine-Associated Cladosporium Species: An Overview on Secondary Metabolites, Biotechnological Relevance, and Biological Activities
Published in Marine drugs (18-11-2021)“…The marine environment is an underexplored treasure that hosts huge biodiversity of microorganisms. Marine-derived fungi are a rich source of novel metabolites…”
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12
Identifying the Anti-MERS-CoV and Anti-HcoV-229E Potential Drugs from the Ginkgo biloba Leaves Extract and Its Eco-Friendly Synthesis of Silver Nanoparticles
Published in Molecules (Basel, Switzerland) (01-02-2023)“…The present study aimed to estimate the antiviral activities of (GB) leaves extract and eco-friendly free silver nanoparticles (Ag NPs) against the MERS-CoV…”
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13
New xanthones and cytotoxic constituents from Garcinia mangostana fruit hulls against human hepatocellular, breast, and colorectal cancer cell lines
Published in Journal of ethnopharmacology (23-02-2017)“…Cancer has proceeded to surpass one of the most chronic illnesses to be the major cause of mortality in both the developing and developed world. Garcinia…”
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14
Litchi chinensis: medicinal uses, phytochemistry, and pharmacology
Published in Journal of ethnopharmacology (04-11-2015)“…Litchi chinensis Sonn. (Sapindaceae) has been widely used in many cultures for the treatment of cough, flatulence, stomach ulcers, diabetes, obesity,…”
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15
Synthesis and chemiluminescent characteristics of two new acridinium esters
Published in Luminescence (Chichester, England) (01-11-2023)“…Two new acridinium esters with a 2-(succinimidyloxycarbonyl)ethyl side arm, namely…”
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16
Lattice-charge imbalance and redox catalysis over perovskite-type ferrite- and manganite-based mixed oxides as studied by XRD, FTIR, UV–Vis DRS, and XPS
Published in Scientific reports (08-05-2023)“…In the present investigation, two sets of pure and substituted ferrite- and manganite-based mixed oxides were prepared within the stoichiometric formula A 1 -…”
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17
A review of green methods for phyto-fabrication of hematite (α-Fe2O3) nanoparticles and their characterization, properties, and applications
Published in Heliyon (01-01-2021)“…The aim of the current work is the introduction of a quick and simple literature survey about the bio-fabrication of the Alpha Hematite nanoparticles (α-Fe2O3)…”
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18
Square-wave Adsorptive Anodic Stripping Voltammetric Determination of Antidiabetic Drug Linagliptin in Pharmaceutical Formulations and Biological Fluids Using a Pencil Graphite Electrode
Published in Analytical Sciences (10-09-2020)“…A simple, sensitive, low-cost, quick and reliable square-wave anodic stripping voltammetric method is described for the determination of the antidiabetic drug…”
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19
Transition-Metal-Mediated Chemo- and Stereoselective Total Synthesis of (−)-Galanthamine
Published in Journal of organic chemistry (21-01-2022)“…An asymmetric synthetic route to (−)-galanthamine (1), a pharmacologically active Amaryllidaceae alkaloid used for the symptomatic treatment of early onset…”
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20
Baicalin; a promising chemopreventive agent, enhances the antitumor effect of 5-FU against breast cancer and inhibits tumor growth and angiogenesis in Ehrlich solid tumor
Published in Biomedicine & pharmacotherapy (01-02-2022)“…Despite considerable advances in cancer treatment, chemotherapy remains a cornerstone in breast cancer therapy. Therefore, reducing chemoresistance and adverse…”
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